C−P Bond Formation by Nickel or Cobalt Catalyzed Coupling Reactions

Chemistry - An Asian Journal, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Abstract This review discloses nickel‐ and cobalt‐catalyzed coupling reactions that allow C−P bond formation. Activation of C−halide bonds to form phosphonium, pentavalent phosphorus, or trivalent phosphorous compounds has been reported with both metals. However, the conversion C−O ((activated) ethers, carbonates, acetates) into ones only described Ni. Similarly, there are more examples C−Y (Y=C, S, N, B) activations catalyzed by Ni than Co. Nevertheless, cross‐dehydrogenative reaction between a P−H reagent C−H often cobalt nickel. In addition, for metals, electrolytic photocatalytic processes have shown produce variety containing molecules. aims provide an overview potential metals formation highlight remaining challenges.

Language: Английский

Micelle-Enabled In Situ Surface Modification of Porous Organic Polymers: Formation of Heterogeneous Microcolony for Efficient Suzuki–Miyaura Coupling in Water

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

Synthesis of water-stable and dispersible heterogeneous catalysts having high catalytic efficiency is more challenging compared with homogeneous due to their low dispersity, activity, spatial confinement active centers in bulk water. Herein, we are describing systematic studies for the development microconfinement participation aqueous micelles via temporal surface modification porous organic polymer derived from phosphine ligands. Detailed investigations using various techniques such as transmission electron microscopy (TEM), scanning (SEM), tensiometry, confocal laser (CLSM), fluorescence lifetime imaging (FLIM) have been used understand role micelles, reagents, materials generation microcolonies Two-color crossover experiments also performed exchange reagents or vice versa, materials. The surfactant-modified ligation stabilization palladium, which was evidenced by high-resolution (HR-TEM), high-angle annular dark-field (HAADF-STEM), X-ray photoelectron spectroscopy (XPS) analysis. act confined space catalysis water showcasing Suzuki-Miyaura cross-coupling reaction a ppm level Pd loading under mild conditions. catalyst found be recyclable five cycles; easy scale-up C-C couplings additional features. Moreover, these data provide an opportunity revising models micellar systems that underpin sustainable

Language: Английский

Tf₂O/DMSO-Promoted Umpolung Phosphorylation for C(sp²)–P or C(sp³)–P Bond Formation

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 10, 2025

We have developed an umpolung method utilizing the Tf2O/DMSO-based system for C(sp2)-P bond or C(sp3)-P formation. This employs both P(O)-H and P(O)-OH compounds as phosphorus sources demonstrates excellent compatibility with a wide range of Grignard reagents. Without requirement precious transition metals additives, this one-pot protocol provides practical efficient synthetic pathway to variety aryl alkyl phosphine oxides. The broad substrate scope diverse applications highlight utility method.

Language: Английский