Optimizing Cupriavidus necator H16 as a host for aerobic C1 conversion

Current Opinion in Biotechnology, Journal Year: 2025, Volume and Issue: 93, P. 103306 - 103306

Published: April 24, 2025

Biological systems capable of converting CO2 or CO2-derived, single-carbon (C1) compounds can be used to reduce reverse carbon emissions while establishing a circular bioeconomy provide sustainable sources the fuels, foods, and materials humanity relies on. A robust will rely upon variety microorganisms assimilating C1 them valuable products at industrial scale. While anaerobic microbes are ideal hosts for production short-chain acids alcohols, aerobic respiration well suited biosynthesis higher molecular weight products. One such organism is gram-negative soil bacterium Cupriavidus necator, which has been utilized in commercial biopolymers decades. More recently, its capability robust, growth on inspired research efforts that have advanced it toward becoming one leading bacterial C1-based biomanufacturing. This review highlights those context characteristics historically made C. necator an excellent host bioconversion processes: metabolic versatility, ability grow rapidly high cell densities, genetic amenability.

Language: Английский

Single-Atom Nanoarchitectonics for Robotics and Other Functions

ACS Sustainable Chemistry & Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: May 2, 2025

Language: Английский