ACS Nano,
Journal Year:
2019,
Volume and Issue:
13(12), P. 13797 - 13808
Published: Nov. 7, 2019
Antibacterial
agents
with
high
antibacterial
efficiency
and
bacteria-binding
capability
are
highly
desirable.
Herein,
we
describe
the
successful
preparation
of
Cu2WS4
nanocrystals
(CWS
NCs)
excellent
activity.
CWS
NCs
small
size
(∼20
nm)
achieve
more
than
5
log
(>99.999%)
inactivation
both
Staphylococcus
aureus
(Gram-positive)
Escherichia
coli
(Gram-negative)
at
low
concentration
(<2
μg
mL-1)
or
without
ambient
light,
which
is
much
better
most
reported
nanomaterials
(including
Ag,
TiO2,
etc.)
even
widely
used
antibiotics
(vancomycin
daptomycin).
mechanism
study
showed
that
have
enzyme-like
(oxidase
peroxidase)
properties
selective
ability,
greatly
facilitate
production
reactive
oxygen
species
to
kill
bacteria.
Animal
experiments
further
indicated
can
effectively
treat
wounds
infected
methicillin-resistant
(MRSA).
This
work
demonstrates
potential
as
effective
nanozymes
for
treatment
bacterial
infection.
International Journal of Molecular Sciences,
Journal Year:
2016,
Volume and Issue:
17(9), P. 1534 - 1534
Published: Sept. 13, 2016
Recent
advances
in
nanoscience
and
nanotechnology
radically
changed
the
way
we
diagnose,
treat,
prevent
various
diseases
all
aspects
of
human
life.
Silver
nanoparticles
(AgNPs)
are
one
most
vital
fascinating
nanomaterials
among
several
metallic
that
involved
biomedical
applications.
AgNPs
play
an
important
role
nanotechnology,
particularly
nanomedicine.
Although
noble
metals
have
been
used
for
purposes,
focused
on
potential
applications
cancer
diagnosis
therapy.
In
this
review,
discuss
synthesis
using
physical,
chemical,
biological
methods.
We
also
properties
methods
their
characterization.
More
importantly,
extensively
multifunctional
bio-applications
AgNPs;
example,
as
antibacterial,
antifungal,
antiviral,
anti-inflammatory,
anti-angiogenic,
anti-cancer
agents,
mechanism
activity
AgNPs.
addition,
therapeutic
approaches
challenges
therapy
Finally,
conclude
by
discussing
future
perspective
Theranostics,
Journal Year:
2020,
Volume and Issue:
10(20), P. 8996 - 9031
Published: Jan. 1, 2020
Silver
nanoparticles
(AgNPs)
have
been
one
of
the
most
attractive
nanomaterials
in
biomedicine
due
to
their
unique
physicochemical
properties.
In
this
paper,
we
review
state-of-the-art
advances
AgNPs
synthesis
methods,
medical
applications
and
biosafety
AgNPs.
The
methods
include
physical,
chemical
biological
routes.
are
mainly
used
for
antimicrobial
anticancer
therapy,
also
applied
promotion
wound
repair
bone
healing,
or
as
vaccine
adjuvant,
anti-diabetic
agent
biosensors.
This
summarizes
action
mechanisms
AgNPs,
which
involve
release
silver
ions
(Ag+),
generation
reactive
oxygen
species
(ROS),
destruction
membrane
structure.
Despite
these
therapeutic
benefits,
safety
problems
such
potential
toxicity
on
cells,
tissue,
organs
should
be
paid
enough
attention.
Besides,
briefly
introduce
a
new
type
Ag
particles
smaller
than
Ångstrom
(Å,
1
Å
=
0.1
nm)
(AgÅPs),
exhibit
better
activity
lower
compared
with
Finally,
conclude
current
challenges
point
out
future
development
direction
Arabian Journal of Chemistry,
Journal Year:
2015,
Volume and Issue:
12(8), P. 3576 - 3600
Published: Nov. 25, 2015
The
nature
acts
like
a
large
"bio-laboratory"
comprising
of
plants,
algae,
fungi,
yeast,
etc.
which
are
composed
biomolecules.
These
naturally
occurring
biomolecules
have
been
identified
to
play
an
active
role
in
the
formation
nanoparticles
with
distinct
shapes
and
sizes
thereby
acting
as
driving
force
for
designing
greener,
safe
environmentally
benign
protocols
synthesis
nanoparticles.
present
review
targets
comparative
biogenic
mechanisms
using
algae
waste
materials
(agro
presence
biomolecules).
use
not
only
reduces
cost
but
also
minimizes
need
hazardous
chemicals
stimulates
'green
synthesis'.
It
focuses
on
computational
aspects
binding
some
applications
biosynthesized
biomedical,
catalysis
biosensors
fields.
Chemical Society Reviews,
Journal Year:
2013,
Volume and Issue:
43(5), P. 1501 - 1518
Published: Dec. 2, 2013
Despite
the
current
advancement
in
drug
discovery
and
pharmaceutical
biotechnology,
infection
diseases
induced
by
bacteria
continue
to
be
one
of
greatest
health
problems
worldwide,
afflicting
millions
people
annually.
Almost
all
microorganisms
have,
fact,
an
intrinsic
outstanding
ability
flout
many
therapeutic
interventions,
thanks
their
fast
easy-to-occur
evolutionary
genetic
mechanisms.
At
same
time,
big
companies
are
losing
interest
new
antibiotics
development,
shifting
capital
investments
much
more
profitable
research
development
fields.
New
smart
solutions
are,
thus,
required
overcome
such
concerns,
should
combine
feasibility
industrial
production
processes
with
cheapness
effectiveness.
In
this
framework,
nanotechnology-based
solutions,
particular
silver
nanoparticles
(AgNPs),
have
recently
emerged
as
promising
candidates
market
antibacterial
agents.
AgNPs
display,
enhanced
broad-range
antibacterial/antiviral
properties,
synthesis
procedures
quite
cost
effective.
However,
despite
increasing
impact
on
market,
relevant
issues
still
open.
These
include
molecular
mechanisms
governing
AgNPs-bacteria
interactions,
physico-chemical
parameters
underlying
toxicity
prokaryotes,
lack
standardized
methods
materials,
uncertainty
definition
general
strategies
develop
drugs
devices
based
nanosilver.
review,
we
analyze
experimental
data
bactericidal
effects
AgNPs,
discussing
complex
scenario
presenting
potential
drawbacks
limitations
techniques
employed.
Moreover,
after
analyzing
depth
main
involved,
provide
some
strategies/procedures
perform
tests
propose
guidelines
for
design
nanosystems
silver/nanosilver.
