Multi-region assessment of pharmaceutical exposures and predicted effects in USA wadeable urban-gradient streams DOI Creative Commons
Paul M. Bradley, Celeste A. Journey, Daniel T. Button

et al.

PLoS ONE, Journal Year: 2020, Volume and Issue: 15(1), P. e0228214 - e0228214

Published: Jan. 30, 2020

Human-use pharmaceuticals in urban streams link aquatic-ecosystem health to human health. Pharmaceutical mixtures have been widely reported larger due historical emphasis on wastewater-treatment plant (WWTP) sources, with limited investigation of pharmaceutical exposures and potential effects smaller headwater streams. In 2014–2017, the United States Geological Survey measured 111 compounds 308 (261 urban-gradient sites sampled 3–5 times, 47 putative low-impact once) 4 regions across US. Simultaneous multiple (pharmaceutical mixtures) were observed 91% (248 urban-gradient, 32 low-impact), 88 analytes detected all cumulative maximum concentrations up 36,142 ng/L per site. Cumulative detections correlated land use presence/absence permitted WWTP discharges, but also common 75% without WWTP. exposure-activity ratios (EAR) indicated widespread transient high probability molecular vertebrates. Considering individual interactive recognized analytical underestimation pharmaceutical-contaminant (unassessed parent compounds, metabolites, degradates) space, these results demonstrate a nation-wide environmental concern need for watershed-scale mitigation in-stream contamination.

Language: Английский

Transformation of pharmaceuticals during oxidation/disinfection processes in drinking water treatment DOI
Cristina Postigo, Susan D. Richardson

Journal of Hazardous Materials, Journal Year: 2014, Volume and Issue: 279, P. 461 - 475

Published: July 22, 2014

Language: Английский

Citations

212
Endocrine-disrupting chemicals: economic, regulatory, and policy implications DOI
Christopher D. Kassotis, Laura N. Vandenberg, Barbara Demeneix

et al.

The Lancet Diabetes & Endocrinology, Journal Year: 2020, Volume and Issue: 8(8), P. 719 - 730

Published: July 21, 2020

Language: Английский

Citations

200
Impacts of endocrine disrupting chemicals on reproduction in wildlife and humans DOI Creative Commons
Vicki L. Marlatt, Stéphane Bayen, Diana C. Castañeda-Cortés

et al.

Environmental Research, Journal Year: 2021, Volume and Issue: 208, P. 112584 - 112584

Published: Dec. 21, 2021

Endocrine disrupting chemicals (EDCs) are ubiquitous in aquatic and terrestrial environments. The main objective of this review was to summarize the current knowledge impacts EDCs on reproductive success wildlife humans. examples selected often include a retrospective assessment over time discern how effects have changed last several decades. Collectively, evidence summarized here within reinforce concept that reproduction humans is negatively impacted by anthropogenic chemicals, with altering endocrine system function. These observations interfering different aspects axis particularly pronounced for species corroborated laboratory-based experiments (i.e. fish, amphibians, birds). Noteworthy, many these same indicators also observed epidemiological studies mammalian Given vast array strategies used animals, it perhaps not surprising no single disrupted target predictive effects. Nevertheless, there some general features control reproduction, particular, critical role steroid hormones play processes confer high degree susceptibility environmental chemicals. New research needed implications chemical exposures during development potential long-term Future emphasis field-based can form basis more deliberate, extensive, population level monitor contaminant effects, including adverse system, key addressing gaps.

Language: Английский

Citations

174
Water Reuse in EU States: Necessity for Uniform Criteria to Mitigate Human and Environmental Risks DOI
Nikolaos V. Paranychianakis,

M. Salgot,

Shane A. Snyder

et al.

Critical Reviews in Environmental Science and Technology, Journal Year: 2014, Volume and Issue: 45(13), P. 1409 - 1468

Published: Sept. 10, 2014

Water quality criteria are an indispensable part of water reuse projects aiming to ensure the protection public health and environment. In addition, can affect development, acceptance, economic viability projects. Currently no uniform exist, but they diverge, often greatly, between countries states. The authors briefly present evolution worldwide discuss emerging issues related ecological risks that have not addressed adequately in existing criteria. They specifically focus on European Union (EU) their status based published data (or nonexisting) frameworks. Data gathered from agencies reveal a high potential for EU could potentially contribute ensuring fresh is available all sectors protect environment, it has expanded at expected rates. lack was thought as most important cause this delay. lasting recent years, however, several countries, particularly those located Mediterranean basin, established Similarities differences well benefits drawbacks these discussed interpreted with other world. An conclusion enacted Greece, Italy, Spain will probably prevent development increase costs. Moreover, major challenges, future views, necessity establishing common regulations level considered.

Language: Английский

Citations

159
SPION/β-cyclodextrin core–shell nanostructures for oil spill remediation and organic pollutant removal from waste water DOI
Amit Kumar, Gaurav Sharma,

Mu. Naushad

et al.

Chemical Engineering Journal, Journal Year: 2015, Volume and Issue: 280, P. 175 - 187

Published: June 6, 2015

Language: Английский

Citations

147
Ethinyl Estradiol and Other Human Pharmaceutical Estrogens in the Aquatic Environment: A Review of Recent Risk Assessment Data DOI
James P. Laurenson,

Raanan A. Bloom,

Stephen D. Page

et al.

The AAPS Journal, Journal Year: 2014, Volume and Issue: 16(2), P. 299 - 310

Published: Jan. 27, 2014

Language: Английский

Citations

131
Persistence and Potential Effects of Complex Organic Contaminant Mixtures in Wastewater-Impacted Streams DOI
Larry B. Barber, Steffanie H. Keefe,

Greg K. Brown

et al.

Environmental Science & Technology, Journal Year: 2013, Volume and Issue: 47(5), P. 2177 - 2188

Published: Feb. 11, 2013

Natural and synthetic organic contaminants in municipal wastewater treatment plant (WWTP) effluents can cause ecosystem impacts, raising concerns about their persistence receiving streams. In this study, Lagrangian sampling, which the same approximate parcel of water is tracked as it moves downstream, was conducted at Boulder Creek, Colorado Fourmile Iowa to determine in-stream transport attenuation discharged from two secondary WWTPs. Similar stream reaches were evaluated, samples collected multiple sites during summer spring hydrologic conditions. Travel times most downstream (7.4 km) site Creek 6.2 h 9.3 spring, 8.4 km 18 8.8 h, respectively. Discharge measured each site, integrated composite analyzed for >200 including metal complexing agents, nonionic surfactant degradates, personal care products, pharmaceuticals, steroidal hormones, pesticides. The highest concentration (>100 μg L(-1)) compounds detected both WWTP ethylenediaminetetraacetic acid 4-nonylphenolethoxycarboxylate oligomers, persisted least 7 Concentrations pharmaceuticals lower (<1 L(-1)), several compounds, carbamazepine sulfamethoxazole, throughout study reaches. After accounting dilution, a complex mixture showed little persistent streams concentrations with potential implications.

Language: Английский

Citations

124
Endocrine disrupting alkylphenolic chemicals and other contaminants in wastewater treatment plant effluents, urban streams, and fish in the Great Lakes and Upper Mississippi River Regions DOI
Larry B. Barber, Jorge E. Loyo-Rosales, Clifford P. Rice

et al.

The Science of The Total Environment, Journal Year: 2015, Volume and Issue: 517, P. 195 - 206

Published: Feb. 27, 2015

Language: Английский

Citations

120
Concentrations of hormones, pharmaceuticals and other micropollutants in groundwater affected by septic systems in New England and New York DOI

Patrick J. Phillips,

Christopher E. Schubert, Denise M. Argue

et al.

The Science of The Total Environment, Journal Year: 2015, Volume and Issue: 512-513, P. 43 - 54

Published: Jan. 19, 2015

Language: Английский

Citations

116
Suburbanization, estrogen contamination, and sex ratio in wild amphibian populations DOI Open Access
Max R. Lambert,

Geoffrey Giller,

Larry B. Barber

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2015, Volume and Issue: 112(38), P. 11881 - 11886

Published: Sept. 8, 2015

Significance We focus on a critical issue, the influence of human-derived contaminants wildlife populations. Endocrine disrupting chemicals that act through hormonal pathways are capable having large influences even when concentrations relatively low. While there is evidence such endocrine disruption can result from application agricultural pesticides and exposure to wastewater effluent, we have identified diversity within suburban neighborhoods. Sampling populations local frog species, found strong association between degree landscape development offspring sex ratio. Our study points rarely studied contamination sources, like vegetation landscaping impervious surface runoff, may be associated with environments around homes.

Language: Английский

Citations

106