Copper(I)‐Catalyzed Asymmetric 1,4‐Hydroarsination of α,β‐Unsaturated Compounds

Angewandte Chemie, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 18, 2024

Abstract Herein, a copper(I)‐catalyzed asymmetric 1,4‐hydroarsination of β‐substituted α,β‐unsaturated esters is achieved in moderate to excellent yields with high enantioselectivity, based on the proposed nucleophilic [Cu]−AsPh 2 species. As for α‐substituted esters, 1,4‐hydroarsination/enantioselective protonation event occurs smoothly satisfying results. Furthermore, ketone, amide, and phosphine sulfide are well applied present catalytic system. Finally, some control experiments show that HAsPh activated through coordination copper(I) catalyst exhibits inferior soft Lewis basicity HPPh presence copper(I)‐bisphosphine complex.

Language: Английский

Tungsten-Catalyzed Stereodivergent Isomerization of Terminal Olefins

Chemical Science, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 4, 2024

A stereodivergent, W-catalyzed alkene isomerization is reported, leading to either E - or Z -β,γ-unsaturated carbonyl compounds based on the ligand environment around metal.

Language: Английский