Hydrofluorination of Alkenes Using Et3N·HF under Dual Cobalt and Photoredox Catalysis DOI Open Access
Martin Oestreich, Hendrik F. T. Klare, Nektarios Kranidiotis‐Hisatomi

et al.

Synfacts, Journal Year: 2024, Volume and Issue: 20(05), P. 0480 - 0480

Published: April 15, 2024

Key words alkenes - cobalt catalysis hydrofluorination photoredox

Language: Английский

Regio- and enantioselective hydrofluorination of internal alkenes via nickel-catalyzed hydrogen atom transfer DOI
Fan Chen, Xiaoyu Zhao,

Weihang Miao

et al.

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110239 - 110239

Published: July 1, 2024

Language: Английский

Citations

1
Practical and regioselective halonitrooxylation of olefins to access β-halonitrates DOI Creative Commons
Cheng Xuan,

Quan Yin,

Yifei Cheng

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Aug. 20, 2024

Organic nitrates, as effective donors of the signaling molecule nitric oxide, are widely applied in pharmaceutical industry. However, practical and efficient methods for accessing organic nitrates still scarce, achieving high regiocontrol unactivated alkene difunctionalization remains challenging. Here we present a simple method highly regioselective halonitrooxylation alkenes. The approach utilizes TMSX (X: Cl, Br, or I) oxybis(aryl-λ

Language: Английский

Citations

1
Shuttle HAT for mild alkene transfer hydrofunctionalization DOI Creative Commons
Tanner C. Jankins, Philip M. Blank,

Andrea Brugnetti

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 30, 2024

Hydrogen atom transfer (HAT) from a metal-hydride is reliable and powerful method for functionalizing unsaturated C-C bonds in organic synthesis. Cobalt hydrides (Co-H) have garnered significant attention this field, where the weak Co-H are most commonly generated catalytic fashion through mixture of stoichiometric amounts peroxide oxidant silane reductant. Here we show that reverse process HAT to an alkene, i.e. hydrogen abstraction C-H adjacent radical, can be leveraged generate catalytically active species application shuttle catalysis coined HAT. This obviates need reductant/oxidant mixtures thereby greatly simplifying generation Co-H. To demonstrate generality platform, five different reaction manifolds shown, easily scaled up 100 mmol.

Language: Английский

Citations

1
Illuminating cobalt co-catalysis DOI
Jianbin Li

Trends in Chemistry, Journal Year: 2024, Volume and Issue: 6(4), P. 161 - 163

Published: March 28, 2024

Language: Английский

Citations

0
Hydrofluorination of Alkenes Using Et3N·HF under Dual Cobalt and Photoredox Catalysis DOI Open Access
Martin Oestreich, Hendrik F. T. Klare, Nektarios Kranidiotis‐Hisatomi

et al.

Synfacts, Journal Year: 2024, Volume and Issue: 20(05), P. 0480 - 0480

Published: April 15, 2024

Key words alkenes - cobalt catalysis hydrofluorination photoredox

Language: Английский

Citations

0