Synlett, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 30, 2024
Abstract Pd-catalyzed cross-couplings of C–H bonds have been pursued by researchers to produce unsymmetrical C–C directly for over 50 years. Such are currently prepared Suzuki, Kumada, Stille, Neigishi, Heck, or Sonogashira coupling C–halogen with C–M bonds. A big challenge is obtain high cross-selectivity cross-coupling products, especially when the substrates similar chemical bonds, such as simple arenes. Lu and co-workers studied Pd catalysis in aryl since 2003. This account introduces their strategy, understanding, research control, activation modes, establishment, discusses applications approach synthesis. 1 Introduction 2 Cross-Selectivity Control 3 Conclusion
Language: Английский