Allylic C–H oxygenation of unactivated internal olefins by the Cu/azodiformate catalyst system
Le Wang,
No information about this author
Yuan She,
No information about this author
Jie Xiao
No information about this author
et al.
Nature Communications,
Journal Year:
2025,
Volume and Issue:
16(1)
Published: Jan. 20, 2025
Language: Английский
Room Temperature, Energy Efficient and Facile Synthesis of Propargyl Functionalized Carbon Dots as Nanosensor for Selective Detection of Pd2+ Ion
CHINMAY TIRTHAKAR,
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Simon Watre Sangma,
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Milan Kumar Dey
No information about this author
et al.
Published: Jan. 1, 2025
Language: Английский
Chemoselective Csp2‐H Radical Alkylation of Aryl Diazonium Salts with 1‐Iodo‐3‐Pentafluorosulfanylbicyclo[1,1,1]pentane (SF5‐BCP‐I)†
Xin Zhao,
No information about this author
Xinyu Li,
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Jia‐Yi Shou
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et al.
Chinese Journal of Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 20, 2025
Comprehensive
Summary
The
reaction
site
of
aryl
diazonium
salt
was
restricted
in
the
position
moiety,
due
to
intrinsic
electrophilicity
moiety.
Herein,
we
described
an
unprecedented
chemoselective
alkylation
Csp
2
‐H
salts
with
1‐iodo‐3‐pentafluorosulfanylbicyclo[1,1,1]pentane
(SF
5
‐BCP‐I).
This
novel
provided
efficient
access
various
SF
‐BCP
substituted
aromatics
that
might
have
great
potential
application
drug
discovery.
Mechanistic
experiments
and
theoretical
studies
revealed
electrophilic
radical
resulted
thermodynamic
favorable
addition
on
rather
than
moiety
salt.
Language: Английский
Palladium/rhodium-catalyzed four-component carbonylative difunctionalization of alkynes: Regio- and stereoselective esterification/selenylation to access β-selenyl acrylates
Journal of Catalysis,
Journal Year:
2025,
Volume and Issue:
unknown, P. 116170 - 116170
Published: April 1, 2025
Language: Английский
Palladium-Catalyzed Oxy-olefination of Styrenes toward Fluoroallyl Ethers
Min Zhao,
No information about this author
Ying Xu,
No information about this author
Yuanhao Zhu
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et al.
ACS Catalysis,
Journal Year:
2025,
Volume and Issue:
unknown, P. 8876 - 8884
Published: May 11, 2025
Language: Английский
Palladium-catalyzed intermolecular asymmetric dearomatizative arylation of indoles and benzofurans
Yang Xi,
No information about this author
Youzhi Xu,
No information about this author
Linlin Fan
No information about this author
et al.
Science Advances,
Journal Year:
2025,
Volume and Issue:
11(22)
Published: May 30, 2025
Indoles
represent
one
of
the
most
robust
and
synthetically
versatile
classes
heteroaromatic
compounds.
However,
stereoselective
conversion
planar
indole
rings
into
three-dimensional
indoline
skeletons
bearing
multiple
stereogenic
centers
remains
a
persistent
challenge
in
organic
synthesis.
Herein,
we
describe
an
intermolecular
catalytic
asymmetric
dearomatization
simple
indoles
via
palladium-catalyzed
three-component
cross-coupling
reaction.
By
using
readily
accessible
diazonium
salts
aromatic
boronic
acids
as
arylative
reagents
under
ligand-swap
strategy,
this
method
enables
efficient
construction
2,3-diarylated
indolines.
Mechanistic
studies
reveal
that
chiral
BiOx
ligand
governs
highly
migratory
insertion
aryl-palladium
intermediate
indole’s
C═C
double
bond
with
complete
diastereo-
regioselectivity,
whereas
achiral
fumarate
facilitates
reductive
elimination
step,
corroborated
by
density
functional
theory
calculations.
Furthermore,
protocol
is
extended
to
dearomative
diarylation
benzofurans,
affording
2,3-dihydrobenzofuran
derivatives
high
stereocontrol.
Language: Английский
Cobalt-Catalyzed Enantioselective Reductive Addition of Ketimine with Cyclopropyl Chloride to Construct the Chiral Amino Esters Bearing Cyclopropyl Fragments
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(22), P. 6311 - 6318
Published: Jan. 1, 2024
Co-catalyzed
asymmetric
reductive
addition
of
ketimine
with
cyclopropyl
chloride
has
been
realized
to
access
diverse
chiral
amino
esters
bearing
fragments
broad
functional
group
tolerance
and
excellent
enantioselectivities.
Language: Английский
Theoretical Investigations of Para-Methoxystyrene/Styrene Polymerization Catalyzed by Cationic Methyl- and Dibenzobarrelene-Based α-Diimine Palladium Complexes
Ling Zhu,
No information about this author
Yi Luo,
No information about this author
Xin Wen
No information about this author
et al.
Inorganics,
Journal Year:
2024,
Volume and Issue:
12(12), P. 315 - 315
Published: Dec. 5, 2024
The
polymerization
mechanism
of
para-methoxystyrene
catalyzed
by
cationic
α-diimine
palladium
complexes
with
various
ancillary
ligands
was
rigorously
examined
using
density
functional
theory.
In
the
classical
methyl-based
complex
[{(2,6-iPr2C6H3)-N=C(Me)-C(Me)=N-2,6-iPr2C6H3)}PdMe]+
(A+),
2,1-insertion
is
favored
over
1,2-insertion,
both
thermodynamically
and
kinetically,
during
chain
initiation
step.
resulting
η3-π-benzyl
intermediates
face
a
substantial
energy
barrier,
yielding
only
trace
amounts
polymer,
as
experimentally
verified.
contrast,
dibenzobarrelene-based
[{(2,6-iPr2C6H3)-N=C(R)-C(R)=N-2,6-iPr2C6H3)}PdMe]+
(R
=
dibenzobarrelene,
B+)
shows
similar
barriers
for
2,1-
1,2-insertions.
Continuous
2,1/2,1
or
2,1/1,2
insertions
are
impeded
excessive
barriers.
However,
theoretical
calculations
reveal
that
1,2-insertion
product
can
seamlessly
transition
into
propagation
stage,
producing
polymer
high
1,2-regioselectivity.
observed
activity
A+
B+
towards
stems
from
barrier
differences
between
1,2-
2,1-insertions,
influenced
steric
hindrance
ligands.
Further
investigation
effects
on
stage
involved
computational
modeling
analogous
increased
bulk.
These
studies
established
direct
correlation
difference
∆∆G
(1,2–2,1)
van
der
Waals
volume
ligand.
Larger
volumes
correspond
to
reduced
differences,
thus
enhancing
regioselectivity
polymerization.
Moreover,
experimental
inertness
styrene
attributed
formation
stable
kinetic
thermodynamic
intermediates,
which
obstruct
further
monomer
insertion
due
an
extremely
reactive
barrier.
findings
contribute
deeper
understanding
mechanistic
aspects
offer
insights
designing
new
metal
catalysts
para-alkoxystyrenes.
Language: Английский
Theoretical study of Ni(0)-catalyzed intermolecular hydroamination of branched 1,3-dienes: reaction mechanism, regioselectivity, enantioselectivity, and prediction of the ligand
Journal of Molecular Modeling,
Journal Year:
2024,
Volume and Issue:
31(1)
Published: Dec. 11, 2024
Language: Английский
Selective Ni(I)/Ni(III) Process for Consecutive Geminal C(sp3)–C(sp2) Bond Formation
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 13, 2024
Ni-catalyzed
multicomponent
cross-couplings
have
emerged
as
a
powerful
strategy
for
efficiently
constructing
complex
molecular
architectures
from
diverse
array
of
organic
halides.
Despite
its
potential,
selectively
forming
multiple
chemical
bonds
in
single
operation,
particularly
the
realm
cross-electrophile
coupling
catalysis,
remains
significant
challenge.
In
this
study,
we
developed
consecutive
open-shell
reductive
Ni
enabling
formation
two
geminal
C(sp
Language: Английский