Rh-Catalyzed Enantioselective Synthesis of Acyclic Quaternary Carbons via Carbene Insertion

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 5273 - 5282

Published: March 13, 2025

Language: Английский

C₄-Symmetric Bowl-Shaped Diruthenium Tetracarboxylate Catalysts for Enantioselective C–H Functionalization Using Donor/Acceptor Carbenes

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Cationic diruthenium (II,III) tetracarboxylate catalysts have been shown to catalyze selective intermolecular C-H functionalization reactions using donor/acceptor carbenes in high yield and with levels of enantioselectivity. The were compared the analogous dirhodium (II,II) showed similar enantioselectivity for most reactions. A distinctive feature is a greater preference over cyclopropanation corresponding catalysts. Also, sterically more accessible sites their counterparts. These studies show that are generally effective enantioselective functionalization, but further optimization would be needed them match terms functional group compatibility, turnover frequency, numbers.

Language: Английский

Chiral metal complexes: Design strategies for precision in asymmetric C–H activation

Journal of Catalysis, Journal Year: 2024, Volume and Issue: unknown, P. 115756 - 115756

Published: Sept. 1, 2024

Language: Английский