Light-modulated self-assembly of synthetic nanotubes DOI Creative Commons
Mahdi Dizani, Siddharth Agarwal, Dino Osmanović

et al.

Published: Nov. 4, 2024

Artificial biomolecular polymers with the capacity to respond stimuli are emerging as a key component develop living materials and synthetic cells. Here, we demonstrate artificial DNA tubular nanostructures that form in response light dose-dependent manner. These nanotubes assemble from programmable tile motifs engineered include UV-responsive domain, so UV irradiation activates nanotube self-assembly. We formation speed can be tuned by adjusting dose. then couple light-dependent activation of tiles RNA transcription, making it possible control via concurrent physical biochemical stimuli. Finally, illustrate how effectively controls assembly confinement, rudimentary stimulus-responsive cytoskeletal system achieve various conformations minimal cell. This study contributes new designs immediately useful build scaffolds controllable dynamics multiple

Language: Английский

Light-Modulated Self-Assembly of Synthetic Nanotubes DOI
Mahdi Dizani, Siddharth Agarwal, Dino Osmanović

et al.

Nano Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 17, 2025

Artificial biomolecular polymers with the capacity to respond stimuli are emerging as a key component development of living materials and synthetic cells. Here, we demonstrate artificial DNA tubular nanostructures that form in response light dose-dependent manner. These nanotubes assemble from programmable tile motifs engineered include UV-responsive domain so UV irradiation activates nanotube self-assembly. We formation speed can be tuned by adjusting dose. then couple light-dependent activation tiles RNA transcription, making it possible control via concurrent physical biochemical stimuli. Finally, illustrate how effectively controls assembly confinement rudimentary stimulus-responsive cytoskeletal system achieve various conformations minimal cell. This study contributes new designs immediately useful building scaffolds controllable dynamics multiple

Language: Английский

Citations

0
Light-modulated self-assembly of synthetic nanotubes DOI Creative Commons
Mahdi Dizani, Siddharth Agarwal, Dino Osmanović

et al.

Published: Nov. 4, 2024

Artificial biomolecular polymers with the capacity to respond stimuli are emerging as a key component develop living materials and synthetic cells. Here, we demonstrate artificial DNA tubular nanostructures that form in response light dose-dependent manner. These nanotubes assemble from programmable tile motifs engineered include UV-responsive domain, so UV irradiation activates nanotube self-assembly. We formation speed can be tuned by adjusting dose. then couple light-dependent activation of tiles RNA transcription, making it possible control via concurrent physical biochemical stimuli. Finally, illustrate how effectively controls assembly confinement, rudimentary stimulus-responsive cytoskeletal system achieve various conformations minimal cell. This study contributes new designs immediately useful build scaffolds controllable dynamics multiple

Language: Английский

Citations

0