Nuclear Magnetic Resonance-Based Approaches for the Structural and Quantitative Analysis of Mycotoxins
Yun Hwan Kim,
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Seon Yeong Lee,
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Jin Young Kim
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et al.
Magnetochemistry,
Journal Year:
2025,
Volume and Issue:
11(6), P. 47 - 47
Published: June 3, 2025
Mycotoxins
are
toxic
secondary
metabolites
produced
by
various
fungal
species,
posing
significant
food
safety
concerns
due
to
their
health
impacts
and
economic
burden.
Accurate
structural
elucidation
quantitative
analysis
essential
for
effective
risk
assessment
regulatory
control.
This
review
highlights
recent
advances
in
the
application
of
nuclear
magnetic
resonance
(NMR)
spectroscopy
major
mycotoxins,
including
aflatoxins,
ochratoxins,
fumonisins,
trichothecenes,
zearalenone.
One-
two-dimensional
NMR
techniques
enable
precise
molecular
characterization,
positional
isomer
identification,
modified
forms
such
as
masked
or
conjugated
toxicity-related
interaction
investigation.
offers
superior
resolution,
high
reproducibility,
nondestructive
analysis,
making
it
invaluable
mycotoxin
research.
Quantitative
has
emerged
a
robust
accurate
method
determining
absolute
concentration
purity
without
requiring
analyte-specific
reference
standards,
an
advantage
particularly
important
toxins
lacking
commercially
available
standards.
The
integration
NMR-based
approaches
strengthens
analytical
reliability,
supports
material
development,
contributes
enhanced
assessment.
also
discusses
ongoing
challenges
future
directions,
artificial
intelligence
improve
automation
interpretation
data
Language: Английский
Hot off the Press
Natural Product Reports,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
A
personal
selection
of
32
recent
papers
is
presented
covering
various
aspects
current
developments
in
bioorganic
chemistry
and
novel
natural
products,
such
as
shimianolide
from
Chloranthus
holostegius
var.
shimianensis
.
Language: Английский