Anti-MRSA and cytotoxic activity of a new diamide compound isolated from Aspergillus sp. H30

Natural Product Research, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 7

Published: March 17, 2025

A new aromatic diamide compound, aspergillusin (1), together with three known compounds, globosterol (2), ergosterol (3), and cladosporide (4), was isolated from the crude extract of endophytic fungi Aspergillus sp. H30. The structures were elucidated using NMR MS data, finally, biosynthetic pathway compound 1 hypothesised. Compounds 1–4 tested for their antibacterial activities on six pathogenic bacteria also evaluated against human non-small cell lung cancer H1299. Among them, exhibited weak activity MRSA a strong effect bronchial epithelial line, BEAS-2B, an IC50 value 12.32 ± 0.37 μM.

Language: Английский

---

Unlocking the brain's code: The crucial role of post-translational modifications in neurodevelopment and neurological function

Physics of Life Reviews, Journal Year: 2025, Volume and Issue: 53, P. 187 - 214

Published: March 23, 2025

Language: Английский

---

Photoinduced Ligand-to-Copper Charge Transfer for Deca- rboxylative Hydrogenation of Aromatic Carboxylic Acids

Tetrahedron, Journal Year: 2025, Volume and Issue: unknown, P. 134536 - 134536

Published: Feb. 1, 2025

Language: Английский

---

Oxygen vacancy mediated oxidative reforming of polylactic acid to hydrocarbon

Applied Catalysis B Environment and Energy, Journal Year: 2025, Volume and Issue: unknown, P. 125413 - 125413

Published: April 1, 2025

Language: Английский

---