A robust, agnostic molecular biosignature based on machine learning
Proceedings of the National Academy of Sciences,
Journal Year:
2023,
Volume and Issue:
120(41)
Published: Sept. 25, 2023
The
search
for
definitive
biosignatures—unambiguous
markers
of
past
or
present
life—is
a
central
goal
paleobiology
and
astrobiology.
We
used
pyrolysis–gas
chromatography
coupled
to
mass
spectrometry
analyze
chemically
disparate
samples,
including
living
cells,
geologically
processed
fossil
organic
material,
carbon-rich
meteorites,
laboratory-synthesized
compounds
mixtures.
Data
from
each
sample
were
employed
as
training
test
subsets
machine-learning
methods,
which
resulted
in
model
that
can
identify
the
biogenicity
both
contemporary
ancient
samples
with
~90%
accuracy.
These
methods
do
not
rely
on
precise
compound
identification:
Rather,
relational
aspects
chromatographic
peaks
provide
needed
information,
underscores
this
method’s
utility
detecting
alien
biology.
Language: Английский
The Average Symmetry Index of Minerals Co-Varies with Their Hydrogen Content, Rarity, and Paragenetic Mode
Minerals,
Journal Year:
2024,
Volume and Issue:
14(4), P. 387 - 387
Published: April 8, 2024
Variations
in
the
Dolivo-Dobrovol’sky
symmetry
index
for
minerals
through
time
reveal
several
factors
that
influence
emergence
of
crystalline
natural
processes.
Of
special
interest
this
regard
are
numerous
paragenetic
modes—different
processes
mineral
genesis
reflect
changes
physical,
chemical,
and
ultimately
biological
environments
foster
new
species.
Here,
we
consider
roles
hydrogen
content,
rarity,
formation
temperature
pressure,
age
on
average
from
57
different
modes
(i.e.,
modes).
We
find
four
significant
trends
all
each
mode:
specifically,
is
(1)
lower
with
greater
content;
(2)
formed
at
higher
pressure;
(3)
rarity;
(4)
older
modes.
These
findings
elucidate
some
intricate
relationships
among
modes,
attributes,
index,
providing
insights
into
geological
governing
formation.
Language: Английский
An Overview of Exoplanet Biosignatures
Reviews in Mineralogy and Geochemistry,
Journal Year:
2024,
Volume and Issue:
90(1), P. 465 - 514
Published: July 1, 2024
Language: Английский
An Informational–Entropic Approach to Exoplanet Characterization
Sara Vannah,
No information about this author
Ian D. Stiehl,
No information about this author
Marcelo Gleiser
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et al.
Entropy,
Journal Year:
2025,
Volume and Issue:
27(4), P. 385 - 385
Published: April 4, 2025
In
the
past,
measures
of
“Earth-likeness”
exoplanets
have
been
qualitative,
considering
an
abiotic
Earth,
or
requiring
discretionary
choices
what
parameters
make
a
planet
Earth-like.
With
advent
high-resolution
exoplanet
spectroscopy,
there
is
growing
need
for
method
quantifying
Earth-likeness
that
addresses
these
issues
while
making
use
data
available
from
modern
telescope
missions.
this
work,
we
introduce
informational–entropic
metric
makes
spectrum
to
directly
quantify
how
Earth-like
is.
To
illustrate
our
method,
generate
simulated
transmission
spectra
series
and
super-Earth
exoplanets,
as
well
exoJupiter
several
gas
giant
exoplanets.
As
proof
concept,
demonstrate
ability
information
evaluate
similar
it
powerful
tool
in
search
candidate
Earth
2.0.
Language: Английский
A Complex Systems Approach to Exoplanet Atmospheric Chemistry: New Prospects for Ruling Out the Possibility of Alien Life As We Know It
The Planetary Science Journal,
Journal Year:
2025,
Volume and Issue:
6(5), P. 116 - 116
Published: May 1, 2025
Abstract
The
near-term
ability
to
characterize
terrestrial
exoplanet
atmospheres
may
bring
us
closer
discovering
alien
life
through
atmospheric
data.
However,
remotely
detectable
candidate
biosignature
gases
are
subject
false-positive
signals
because
they
can
also
be
produced
abiotically,
raising
a
critical
need
develop
methods
determine
whether
gas
is
abiotically
or
not.
To
distinguish
biological,
abiotic,
and
anomalous
sources
(unidentified
as
abiotic
biotic)
of
gases,
we
take
complex
systems
approach
implementing
chemical
reaction
network
analysis
planetary
atmospheres.
We
simulated
30,000
atmospheres,
organized
in
two
data
sets:
Archean-Earth-like
worlds
modern-Earth-like
worlds.
For
worlds,
study
cases
where
CH
4
via
serpentinization,
biologically
methanogenesis,
from
sources.
simulate
with
without
industrial
CFC-12.
show
how
properties
effectively
scenarios
methanogenesis
serpentinization.
Network
distinguishes
CFC-12
those
it.
Using
Bayesian
analysis,
demonstrate
statistics
provide
stronger
confidence
for
ruling
out
biological
explanations
compared
abundance
alone.
Our
results
confirm
theoretic
allows
distinguishing
hypotheses
about
drivers
and,
importantly,
know
it
possible
explanation.
conclude
discussion
further
developing
statistical
inference
spectral
that
incorporate
could
significantly
strengthen
future
detection
efforts.
Language: Английский
Direct Analysis of Complex Reaction Mixtures: Formose Reaction
Angewandte Chemie International Edition,
Journal Year:
2023,
Volume and Issue:
63(6)
Published: Dec. 15, 2023
Complex
reaction
mixtures,
like
those
postulated
on
early
Earth,
present
an
analytical
challenge
because
of
the
number
components,
their
similarity,
and
vastly
different
concentrations.
Interpreting
networks
is
typically
based
simplified
or
partial
data,
limiting
our
insight.
We
a
new
approach
online
monitoring
mixtures
formed
by
formose
ion-mobility-separation
mass-spectrometry.
Monitoring
led
to
large
data
sets
that
we
analyzed
non-negative
matrix
factorization,
thereby
identifying
ion-signal
groups
capturing
time
evolution
network.
The
comprised
≈300
major
ion
signals
corresponding
sugar-calcium
complexes
during
reaction.
Multivariate
analysis
kinetic
profiles
these
provided
overview
interconnected
processes
in
solution,
highlighting
pathways
for
sugar
growth
effects
initiators
initial
kinetics.
Reconstructing
network's
topology
further,
revealed
so
far
unnoticed
fast
retro-aldol
ketoses,
which
significantly
affects
dynamics.
also
detected
onset
sugar-backbone
branching
C
Language: Английский
An information theory approach to identifying signs of life on transiting planets
Monthly Notices of the Royal Astronomical Society Letters,
Journal Year:
2023,
Volume and Issue:
528(1), P. L4 - L9
Published: Oct. 17, 2023
ABSTRACT
Can
information
theory
provide
insights
into
whether
exoplanets
are
habitable?
Here,
we
apply
to
a
range
of
simulated
exoplanet
transmission
spectra
as
diagnostic
tool
search
for
potential
signatures
life
on
Earth-analogue
planets.
We
test
the
algorithms
three
epochs
evolution
Earth-like
planets
orbiting
host
stars.
The
JWST
and
upcoming
ground-
space-based
missions
promise
achieve
sufficient
high-resolution
data
that
can
be
applied
assess
habitability.
This
approach
provides
framework
observers
an
shows
signs
Language: Английский
Direct Analysis of Complex Reaction Mixtures: Formose Reaction
Angewandte Chemie,
Journal Year:
2023,
Volume and Issue:
136(6)
Published: Dec. 15, 2023
Abstract
Complex
reaction
mixtures,
like
those
postulated
on
early
Earth,
present
an
analytical
challenge
because
of
the
number
components,
their
similarity,
and
vastly
different
concentrations.
Interpreting
networks
is
typically
based
simplified
or
partial
data,
limiting
our
insight.
We
a
new
approach
online
monitoring
mixtures
formed
by
formose
ion‐mobility‐separation
mass‐spectrometry.
Monitoring
led
to
large
data
sets
that
we
analyzed
non‐negative
matrix
factorization,
thereby
identifying
ion‐signal
groups
capturing
time
evolution
network.
The
comprised
≈300
major
ion
signals
corresponding
sugar‐calcium
complexes
during
reaction.
Multivariate
analysis
kinetic
profiles
these
provided
overview
interconnected
processes
in
solution,
highlighting
pathways
for
sugar
growth
effects
initiators
initial
kinetics.
Reconstructing
network's
topology
further,
revealed
so
far
unnoticed
fast
retro‐aldol
ketoses,
which
significantly
affects
dynamics.
also
detected
onset
sugar‐backbone
branching
C
6
sugars
cyclization
reactions
starting
5
sugars.
This
top‐down
opens
way
analyze
complex
dynamic
with
unprecedented
coverage
resolution.
Language: Английский
The Process We Call Earth: Relationships Between Dynamic Feedbacks and the Search for Gaiasignatures in a New Paradigm of Earthlikeness
Perspectives of Earth and Space Scientists,
Journal Year:
2024,
Volume and Issue:
5(1)
Published: March 6, 2024
Abstract
Standard
notions
of
an
“Earthlike”
planet
rely
solely
on
physical
and
material
properties,
like
planetary
mass,
radius,
surface
temperature.
Here,
we
introduce
a
novel,
relational
perspective
what
defines
“Earthlikeness.”
In
our
process‐based
framework,
rocky
planets
are
local
pockets
free
energy
that
have
the
potential
to
drive
emergence
dynamically
persistent
systems
coevolve
with
one
another.
Examples
phenomena
include
magnetic
dynamos,
mantle
convection,
tectonic
regimes,
deep
volatile
cycles,
global
climate
feedbacks,
biogeochemical
biosphere.
When
two
or
more
processes
couple
another
such
they
gain
causal
efficacy
over
another's
persistence,
some
degree
planetary‐scale
homeostasis
may
emerge.
astrobiology,
Earthlike
exoplanets
often
considered
be
priority
targets
for
search
life
elsewhere.
We
suggest
framework
Earthlikeness
has
widen
space
inspire
novel
biosignatures,
“Gaiasignatures,”
essential
detecting
exoplanetary
biospheres.
Additionally,
view
can
influence
development
agnostic
biosignatures
at
all
scales.
contrast
dominant
scientific
perspective,
which
tended
engender
materialistic
worldview,
ontologies
contribute
understanding
Earth
as
network
systems,
humanity
integral
part
nature,
in
universe.
Language: Английский