The industrial melanism mutation in British peppered moths is a transposable element

Nature, Journal Year: 2016, Volume and Issue: 534(7605), P. 102 - 105

Published: June 1, 2016

Language: Английский

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Genomic architecture and introgression shape a butterfly radiation

Science, Journal Year: 2019, Volume and Issue: 366(6465), P. 594 - 599

Published: Oct. 31, 2019

We used 20 de novo genome assemblies to probe the speciation history and architecture of gene flow in rapidly radiating Heliconius butterflies. Our tests distinguish incomplete lineage sorting from introgression indicate that has obscured several ancient phylogenetic relationships this group over large swathes genome. Introgressed loci are underrepresented low-recombination gene-rich regions, consistent with purging foreign alleles more tightly linked incompatibility loci. Here, we identify a hitherto unknown inversion traps color pattern switch locus. infer was transferred between lineages by is convergent similar rearrangement another part genus. These multiple sequences enable improved understanding importance selective processes adaptive radiation.

Language: Английский

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Recombination rate variation shapes barriers to introgression across butterfly genomes

PLoS Biology, Journal Year: 2019, Volume and Issue: 17(2), P. e2006288 - e2006288

Published: Feb. 7, 2019

Hybridisation and introgression can dramatically alter the relationships among groups of species, leading to phylogenetic discordance across genome between populations. Introgression also erode species differences over time, but selection against at certain loci acts maintain postmating barriers. Theory predicts that barriers made up many throughout should lead a broad correlation recombination rate, which determines extent on deleterious foreign alleles will affect neutral physically linked loci. Here, we describe variation in genealogical three Heliconius butterflies: H. melpomene (mel), cydno (cyd), timareta (tim), using whole genomes 92 individuals, ask whether this be explained by heterogeneous introgression. We find vary predictably chromosomal scale. By quantifying rate admixture proportions, then show rates are predicted rate. This implies highly polygenic, with acting introgressed most genome. In addition, long chromosomes, have lower rates, produce stronger average than short chromosomes. Finally, consistent difference two pairs either side Andes, suggests architecture Our findings illustrate how combined effects hybridisation, recombination, natural selection, multitudes periods, sculpt species.

Language: Английский

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Complex modular architecture around a simple toolkit of wing pattern genes

Nature Ecology & Evolution, Journal Year: 2017, Volume and Issue: 1(3)

Published: Jan. 27, 2017

Language: Английский

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Genetic architecture and balancing selection: the life and death of differentiated variants

Molecular Ecology, Journal Year: 2017, Volume and Issue: 26(9), P. 2430 - 2448

Published: Feb. 7, 2017

Abstract Balancing selection describes any form of natural selection, which results in the persistence multiple variants a trait at intermediate frequencies within populations. By offering up snapshot co‐occurring functional and their interactions, systems under balancing can reveal evolutionary mechanisms favouring emergence adaptive variation We here focus on by several for given arise, process typically requiring epistatic mutations. highlight how favour specific features genetic architecture review molecular shaping this architecture. First, affects number loci underlying differentiated traits respective effects. Control one or few favours limiting intergenic recombination, its impact, may sometimes lead to evolution supergenes. Chromosomal rearrangements, particularly inversions, preventing combinations from being dissociated are increasingly noted as such systems. Similarly, due frequency heterozygotes maintained dominance be key property variants. High heterozygosity limited recombination also influence associated load, linked recessive deleterious mutations sheltered. The capture elements locus reinforce polymorphism further promoting heterozygotes. Finally, according recent genomewide scans, balanced might more pervasive than generally thought. stress need both ecological studies characterize operating these

Language: Английский

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Mutation load at a mimicry supergene sheds new light on the evolution of inversion polymorphisms

Nature Genetics, Journal Year: 2021, Volume and Issue: 53(3), P. 288 - 293

Published: Jan. 25, 2021

Language: Английский

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Genetics of adaptation

Proceedings of the National Academy of Sciences, Journal Year: 2022, Volume and Issue: 119(30)

Published: July 18, 2022

The rediscovery of Mendel's work showing that the heredity phenotypes is controlled by discrete genes was followed reconciliation Mendelian genetics with evolution natural selection in middle last century Modern Synthesis. In past two decades, dramatic advances genomic methods have facilitated identification loci, genes, and even individual mutations underlie phenotypic variants are putative targets selection. Moreover, these also changed how we can study adaptation flipping problem around, allowing us to first examine what loci show evidence having been under selection, then connecting genetic variation. As a result, now an expanding list actual changes potentially adaptive Here, synthesize considering effects context cellular environments, genomes, organisms, populations has provided new insights architecture adaptation.

Language: Английский

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Lepidoptera: Moths and Butterflies

Elsevier eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 548 - 566

Published: Oct. 4, 2023

Language: Английский

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Single master regulatory gene coordinates the evolution and development of butterfly color and iridescence

Proceedings of the National Academy of Sciences, Journal Year: 2017, Volume and Issue: 114(40), P. 10707 - 10712

Published: Sept. 18, 2017

Significance The optix gene is well known for its genetic association with wing pattern variation in butterflies; however, actual function has never been directly confirmed. Using CRISPR genome editing multiple butterfly species, we show that this plays a fundamental and deeply conserved role the family Nymphalidae, where it acts as an activator of color. We were also surprised to discover simultaneously controls blue iridescence some species well, providing example how single can act switch coordinate between structural pigmentary coloration.

Language: Английский

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Supergene Evolution Triggered by the Introgression of a Chromosomal Inversion

Current Biology, Journal Year: 2018, Volume and Issue: 28(11), P. 1839 - 1845.e3

Published: May 24, 2018

Language: Английский

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