Angewandte Chemie International Edition,
Journal Year:
2018,
Volume and Issue:
57(48), P. 15664 - 15669
Published: Oct. 8, 2018
Abstract
The
selective
functionalization
of
chemically
inert
C−H
bonds
remains
to
be
fully
realized
in
achieving
organic
transformations
that
are
redox‐neutral,
waste‐limiting,
and
atom‐economical.
catalytic
generation
chlorine
atoms
from
chloride
ions
is
one
the
most
challenging
redox
processes,
where
requirement
harsh
oxidizing
reaction
conditions
renders
it
seldom
utilized
synthetic
applications.
We
report
mild,
controlled,
as
a
new
opportunity
for
access
wide
variety
hydrogen
atom
transfer
(HAT)
reactions
owing
high
stability
HCl.
discovery
photoredox
mediated
with
Ir‐based
polypyridyl
complex,
[Ir(dF(CF
3
)ppy)
2
(dtbbpy)]Cl,
under
blue
LED
irradiation
reported.
Angewandte Chemie International Edition,
Journal Year:
2018,
Volume and Issue:
58(4), P. 1213 - 1217
Published: Nov. 12, 2018
We
report
a
visible-light-mediated
organocatalytic
strategy
for
the
enantioselective
acyl
radical
conjugate
addition
to
enals,
leading
valuable
1,4-dicarbonyl
compounds.
The
process
capitalizes
upon
excited-state
reactivity
of
4-acyl-1,4-dihydropyridines
that,
visible-light
absorption,
can
trigger
generation
radicals.
By
means
chiral
amine
catalyst,
iminium
ion
activation
enals
ensures
stereoselective
trap.
also
demonstrate
how
combination
this
acylation
with
second
catalyst-controlled
bond-forming
event
allows
selectively
access
full
matrix
all
possible
stereoisomers
resulting
2,3-substituted
products.
ChemElectroChem,
Journal Year:
2019,
Volume and Issue:
6(16), P. 4067 - 4092
Published: May 23, 2019
Abstract
Organic
electrosynthesis
is
an
enabling
and
sustainable
technology,
which
constitutes
a
rapidly
expanding
field
of
research.
Electrochemical
approaches
serve
as
convenient
green
alternatives
to
stoichiometric
toxic
chemical
redox
agents.
Electrosynthesis
promising
platform
for
harnessing
the
unique
reactivity
profiles
radical
intermediates,
expediting
development
new
reaction
manifolds.
This
Review
highlights
both
anodic
cathodic
methods
construction
various
kinds
complex
molecules.
Angewandte Chemie International Edition,
Journal Year:
2018,
Volume and Issue:
57(48), P. 15664 - 15669
Published: Oct. 8, 2018
Abstract
The
selective
functionalization
of
chemically
inert
C−H
bonds
remains
to
be
fully
realized
in
achieving
organic
transformations
that
are
redox‐neutral,
waste‐limiting,
and
atom‐economical.
catalytic
generation
chlorine
atoms
from
chloride
ions
is
one
the
most
challenging
redox
processes,
where
requirement
harsh
oxidizing
reaction
conditions
renders
it
seldom
utilized
synthetic
applications.
We
report
mild,
controlled,
as
a
new
opportunity
for
access
wide
variety
hydrogen
atom
transfer
(HAT)
reactions
owing
high
stability
HCl.
discovery
photoredox
mediated
with
Ir‐based
polypyridyl
complex,
[Ir(dF(CF
3
)ppy)
2
(dtbbpy)]Cl,
under
blue
LED
irradiation
reported.
