Immunopathogenesis of IBD: current state of the art

Nature Reviews Gastroenterology & Hepatology, Journal Year: 2015, Volume and Issue: 13(1), P. 13 - 27

Published: Dec. 2, 2015

Language: Английский

---

Chemically induced mouse models of acute and chronic intestinal inflammation

Nature Protocols, Journal Year: 2017, Volume and Issue: 12(7), P. 1295 - 1309

Published: June 1, 2017

Language: Английский

---

Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

Nature Genetics, Journal Year: 2015, Volume and Issue: 47(6), P. 598 - 606

Published: May 4, 2015

Language: Английский

---

JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects

Drugs, Journal Year: 2017, Volume and Issue: 77(5), P. 521 - 546

Published: March 3, 2017

Language: Английский

---

Type 2 immunity in tissue repair and fibrosis

Nature reviews. Immunology, Journal Year: 2017, Volume and Issue: 18(1), P. 62 - 76

Published: Aug. 30, 2017

Language: Английский

---

Mechanisms of Disease: Inflammatory Bowel Diseases

Mayo Clinic Proceedings, Journal Year: 2019, Volume and Issue: 94(1), P. 155 - 165

Published: Jan. 1, 2019

Language: Английский

---

Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

Cell, Journal Year: 2019, Volume and Issue: 178(6), P. 1493 - 1508.e20

Published: Aug. 29, 2019

Language: Английский

---

Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

Nature, Journal Year: 2015, Volume and Issue: 525(7569), P. 389 - 393

Published: Aug. 18, 2015

Language: Английский

---

Role of Chlorogenic Acids in Controlling Oxidative and Inflammatory Stress Conditions

Nutrients, Journal Year: 2015, Volume and Issue: 8(1), P. 16 - 16

Published: Dec. 25, 2015

Chlorogenic acids (CGAs) are esters formed between caffeic and quinic acids, represent an abundant group of plant polyphenols present in the human diet. CGAs have different subgroups that include caffeoylquinic, p-coumaroylquinic, feruloyquinic acids. Results epidemiological studies suggest consumption beverages such as coffee, tea, wine, herbal infusions, also some fruit juices is linked to reduced risks developing chronic diseases. These contain concentrations isomeric mixtures. The underlying mechanism(s) for specific health benefits attributed involves mitigating oxidative stress, hence related adverse effects associated with unbalanced intracellular redox state. There evidence show exhibit anti-inflammatory activities by modulating a number important metabolic pathways. This review will focus on three aspects relevance coffee beverages; namely: (1) relative composition CGA isomers (2) analysis vitro vivo individual can mitigate inflammatory stresses; (3) description molecular mechanisms key role cell signaling activity underlines functions.

Language: Английский

---

Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease

Nature Medicine, Journal Year: 2017, Volume and Issue: 23(5), P. 579 - 589

Published: April 3, 2017

Language: Английский

---