
Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16
Published: March 11, 2025
Mitochondrial homeostasis (MH) refers to the dynamic balance of mitochondrial number, function, and quality within cells. Maintaining MH is significant in occurrence, development, clinical treatment Gastrointestinal (GI) tumors. Ubiquitination, as an important post-translational modification mechanism proteins, plays a central role regulation MH. Over past decade, research on by ubiquitination has focused biogenesis, dynamics, Mitophagy, metabolism during these processes. This review summarizes potential therapeutic targets ubiquitin (Ub)-regulated intervention GI
Language: Английский