Effect of Sleep Extension on Objectively Assessed Energy Intake Among Adults With Overweight in Real-life Settings

JAMA Internal Medicine, Journal Year: 2022, Volume and Issue: 182(4), P. 365 - 365

Published: Feb. 7, 2022

Short sleep duration has been recognized as a risk factor for obesity. Whether extending may mitigate this remains unknown.To determine the effects of extension intervention on objectively assessed energy intake, expenditure, and body weight in real-life settings among adults with overweight who habitually curtailed their duration.This single-center, randomized clinical trial was conducted from November 1, 2014, to October 30, 2020. Participants were aged 21 40 years mass index (calculated kilograms divided by height meters squared) between 25.0 29.9 had habitual less than 6.5 hours per night. Data analyzed according intention-to-treat principle.After 2-week period at baseline, participants either an individualized hygiene counseling session that intended extend bedtime 8.5 (sleep group) or continue (control group). All instructed daily routine activities home without any prescribed diet physical activity.The primary outcome change intake which sum total expenditure stores. Total measured doubly labeled water method. Change stores computed using regression weights composition changes dual-energy x-ray absorptiometry. Sleep monitored actigraphy. Changes baseline compared 2 groups analysis.Data 80 (mean [SD] age, 29.8 [5.1] years; 41 men [51.3%]) analyzed. increased approximately 1.2 night (95% CI, 1.0 1.4 hours; P < .001) group vs control group. The significant decrease (-270 kcal/d; 95% -393 -147 .001). inversely correlated (r = -0.41; -0.59 -0.20; No treatment effect found, resulting reduction group.This found reduced resulted negative balance duration. Improving maintaining healthy over longer periods could be part obesity prevention loss programs.ClinicalTrials.gov Identifier: NCT02253368.

Language: Английский

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Associations between sleep variability and cardiometabolic health: A systematic review

Sleep Medicine Reviews, Journal Year: 2022, Volume and Issue: 66, P. 101688 - 101688

Published: Aug. 21, 2022

Language: Английский

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The emerging importance of tackling sleep–diet interactions in lifestyle interventions for weight management

British Journal Of Nutrition, Journal Year: 2022, Volume and Issue: 128(3), P. 561 - 568

Published: May 23, 2022

Abstract Sleep habits are directly related to risk of obesity, and this relationship may be partly mediated through food choices eating behaviour. Short sleep duration, impaired quality suboptimal timing all implicated in weight gain adverse cardiometabolic health, at least their associations with diet quality. Short-term restriction leads increased energy intake, habitually short sleepers report dietary intakes that indicate a less healthy compared adequate sleepers. Evidence is emerging extension interventions reduce intake sugars overall intake. Poor quality, night shift work patterns social jetlag also associated lower consumption energy-dense foods. Incorporating advice into management more effective than energy-restricted diets exercise alone. However, there lack intervention studies aim lengthen sleep, improve or adjust irregular investigate the impact on behaviour participants aiming lose maintain loss. Finally, future research should take account individual characteristics such as age, sex, life stage changing working practices when designing combined lifestyle including change for health well-being.

Language: Английский

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Sleep extension and cardiometabolic health: what it is, possible mechanisms and real‐world applications

The Journal of Physiology, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 24, 2024

Abstract Short sleep duration is associated with heightened cardiometabolic disease risk and has reached epidemic proportions among children, adolescents adults. Potential mechanisms underlying this association are complex multifaceted, including disturbances in circadian timing, food intake appetitive hormones, brain regions linked to control of hedonic eating, physical activity, an altered microbiome impaired insulin sensitivity. Sleep extension, or increasing total duration, emerging ecologically relevant intervention significant potential advance our understanding the between short disease. If effective, extension interventions have improve health across lifespan. Existing data show that feasible might benefits, although there limitations field must overcome. Notably, most existing studies term (2–8 weeks), use different strategies, analyse a wide array outcomes populations and, frequently, lack adequate statistical power, thus limiting robust scientific conclusions. Overcoming these will require fully powered, randomized conducted people habitual factors. Additionally, controlled trials comparing strategies essential determine effective interventions. Ongoing future research should focus on elucidating benefits extension. Such high generate crucial knowledge quality life for those struggling duration. image

Language: Английский

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Sleep Health

Clinical and Translational Neuroscience, Journal Year: 2024, Volume and Issue: 8(1), P. 8 - 8

Published: Jan. 24, 2024

Together with (physical and mental) exercise, diet, social activities, sleep is a key health behavior that occupies one third of our lives, yet remains neglected. In the first part this review, we present current knowledge on how promotes body, brain, mental, occupational, as well creativity, productivity, well-being. second part, discuss good screening for sleep–wake disorders may improve reduce burden cardiovascular, metabolic cancer. We also review literature measurements Bernese Sleep Health Questionnaire, new simple tool to assess screen circadian in clinical practice.

Language: Английский

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Sleep Health

Ural Medical Journal, Journal Year: 2025, Volume and Issue: 24(1), P. 159 - 178

Published: March 3, 2025

Together with (physical and mental) exercise, diet, social activities, sleep is a key health behavior that occupies one third of our lives, yet remains neglected. In the first part this review, we present current knowledge on how promotes body, brain, mental, occupational, as well creativity, productivity, well-being. second part, discuss good screening for sleep–wake disorders may improve reduce burden cardiovascular, metabolic cancer. We also review literature measurements Bernese Sleep Health Questionnaire, new simple tool to assess screen circadian in clinical practice.

Language: Английский

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Global Perspectives on Sleep Health: Definitions, Disparities, and Implications for Public Health

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(3), P. 304 - 304

Published: March 13, 2025

Sleep health is a multidimensional construct encompassing sleep quality, duration, efficiency, regularity, and alignment with circadian rhythms, playing crucial role in overall well-being. remains inconsistently defined across research clinical settings despite its importance, limiting the ability to standardize assessments interventions. Recent studies have emphasized significance of defining beyond absence disorders, integrating subjective objective measures assess impact on physical mental outcomes. Disparities exist gender, socioeconomic status, geographic regions, particularly low- middle-income countries where inconsistent work schedules, economic stress, healthcare access influence patterns. Poor associated increased risks cardiovascular disease, obesity, metabolic dysfunction, reinforcing as modifiable risk factor public health. Lifestyle factors such caffeine consumption, activity, irregular eating patterns also contribute disturbances, highlighting need for behavioral This narrative review aims synthesize current knowledge health, focusing definitions, measurement tools, global disparities, associations.

Language: Английский

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Overnight Fasting and Body Weight: Emulated Target Trial Using Cancer Prevention Study-3 Data

Nutrients, Journal Year: 2025, Volume and Issue: 17(9), P. 1559 - 1559

Published: April 30, 2025

Background/Objectives: Intermittent fasting has gained attention in managing weight, yet its long-term effects remain unclear. We examined the impact of overnight, before-sleep, and after-sleep on body weight over two years using data from Cancer Prevention Study-3 Diet Assessment Substudy. Methods: emulated three target trials 457 adults without diabetes or cancer. Participants were assigned to strategies <12 vs. ≥12 h <4 ≥4 before sleep, <1 ≥1 after sleep at baseline (2016). Mean 2 post was estimated marginal structural models with stabilized inverse probability weights, adjusting for pre-baseline covariates. Results: After (median [IQR]: 2.0 [1.8-2.0] years), mean 79.4 kg (≥12 overnight) 78.9 (<12 (mean difference: 0.4 kg; 95% CI: -4.1 4.7); (≥4 sleep) 77.5 (<4 1.9 -0.4 4.1); 79.8 (≥1 (<1 0.9 -4.3 4.4). Among men, overnight ≥ 12 showed a higher (100.9 83.9 kg, 17.0 10.8, 23.1), whereas, among women, it lower (74.3 77.1 -2.8 -6.8, 1.2). Conclusions: Overall, alone may not substantially influence but sex-specific differences suggest need further investigation.

Language: Английский

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Multidimensional Sleep Health

Oxford University Press eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 367 - 405

Published: May 22, 2025

Abstract Sleep is inextricably linked to health. disorders and the adverse consequences of suboptimal sleep have been a primary focus empirical research clinical medicine. However, do not reflect full spectrum sleep-related experiences. Recently, there has growing interest in better understanding only but also This chapter defines multidimensional health, discusses methods for measuring analyzing health relation outcomes, some specific considers behavioral interventions from framework.

Language: Английский

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Metabolic and vascular imaging markers for investigating Alzheimer’s disease complicated by sleep fragmentation in mice

Frontiers in Physiology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 20, 2024

Background Sleep problem is a common complication of Alzheimer’s disease (AD). Extensive preclinical studies have been performed to investigate the AD pathology. However, pathophysiological consequence complicated by sleep remains be further determined. Purpose To brain metabolism and perfusion in an mouse model problem, subsequently identify potential imaging markers better understand associated pathophysiology. Methods We examined oxygen extraction fraction (OEF), cerebral metabolic rate (CMRO 2 ), blood flow (CBF) using state-of-the-art MRI techniques cohort 5xFAD mice. Additionally, neuroinflammation, indicated activated microglia, was assessed histology techniques. fragmentation (SF) utilized as representative for problems. Results SF with significant increases OEF ( P = 0.023) CMRO 0.029), indicating state hypermetabolism. CBF showed genotype-by-sleep interaction effect 0.026), particularly deep regions such hippocampus thalamus. Neuroinflammation primarily driven genotype rather than SF, especially measurements. Conclusion These results suggest that measurements are promising studying co-pathogenesis SF.

Language: Английский

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