Anti-obesity Medications for Monogenic Syndromic Obesity DOI

Shilpa Chugh Garcha,

Sanjay Kalra

Published: Jan. 1, 2025

Language: Английский

Germany’s 2022 Report Card on Physical Activity for Children and Adolescents DOI Creative Commons
Yolanda Demetriou,

Franziska Beck,

David J. Sturm

et al.

German Journal of Exercise and Sport Research, Journal Year: 2024, Volume and Issue: 54(2), P. 260 - 275

Published: March 1, 2024

Abstract The German Report Card on Physical Activity for Children and Adolescents 2022 provides a summary comprehensive evaluation of physical activity levels correlated indicators using the Active Healthy Kids Canada grading framework. Card, established by Germany (AHK Germany) expert panel, describes to what degree youth meets World Health Organization (WHO) guidelines sedentary behavior. Additionally, distal proximal determinants, settings, as well strategies investments towards improvements in were analyzed assigning grades eleven benchmarks. Most children adolescents failed meet WHO behavior engaged high sitting durations. Therefore, we assigned poor Overall (D−) slightly higher Sedentary Behavior (C). Moderately positive scores observed specific behaviors such Transportation (C) Non-organized Play (C−). Organized Sport Participation was only behavioral indicator receiving good grade (B−). Grades moderately Settings Sources Influence (Family Friends: C; School: B−; Community Environment: B−). For within group Individual Characteristics, able assign Fitness (D+), whereas Overweight Obesity not rated (INC). We also an incomplete Government due need objective criteria policies, indicating data gaps potentially crucial future research.

Language: Английский

Citations

7

Overall volume of antibiotics prescribed, 2020 DOI Open Access

Caroline Penn,

Michael Mueller, David Morgan

et al.

Health at a glance. Europe, Journal Year: 2022, Volume and Issue: unknown

Published: Dec. 20, 2022

Health at a Glance: Europe 2022 marks the start of new State in EU cycle -an initiative launched by European Commission, co-operation with OECD and Observatory on Systems Policies, to assist Member States improving health their citizens performance systems.While preparation this publication was led OECD, Commission provided guidance substantive inputs throughout process, as well financial support via EU4Health Programme.

Language: Английский

Citations

25

Surgery for the treatment of obesity in children and adolescents DOI
Gabriel Torbahn, Jana Brauchmann, Emma Axon

et al.

Cochrane library, Journal Year: 2022, Volume and Issue: 2022(9)

Published: Sept. 8, 2022

Language: Английский

Citations

23

Change of obesity prevalence and lifestyle patterns before and during COVID-19 among Korean adolescents DOI Creative Commons
Hong Kyu Park, Jung Sub Lim

Annals of Pediatric Endocrinology & Metabolism, Journal Year: 2022, Volume and Issue: 27(3), P. 183 - 191

Published: Sept. 29, 2022

Lockdown measure for limiting coronavirus disease 2019 (COVID-19) spread cause an aggravation of the childhood obesity epidemic through lifestyle changes. The aim is to investigate how social restriction might have changed prevalence and patterns in Korean adolescents. We also evaluate most fragile group influencing parameters on prevalence.

Language: Английский

Citations

23

Is COVID-19 to Blame? Trends of Incidence and Sex Ratio in Youth-Onset Type 2 Diabetes in Germany DOI Open Access
Christian Denzer, Joachim Rosenbauer,

Daniela Klose

et al.

Diabetes Care, Journal Year: 2023, Volume and Issue: 46(7), P. 1379 - 1387

Published: May 4, 2023

OBJECTIVE We investigated the incidence of pediatric type 2 diabetes (T2D) in Germany during years coronavirus disease 2019 (COVID-19) pandemic (2020–2021) compared with control period 2011–2019. RESEARCH DESIGN AND METHODS Data on T2D children (aged 6 to <18 years) were obtained from DPV (German Diabetes Prospective Follow-up) Registry. Poisson regression was used estimate incidences for 2020 and 2021 based data 2011 2019, these observed by estimating rate ratios (IRRs) 95% CIs. RESULTS Incidence youth-onset increased 0.75 per 100,000 patient-years (PYs) (95% CI 0.58, 0.93) 1.25 PYs 1.02, 1.48), an annual increase 6.8% 4.1, 9.6). In 2020, 1.49 1.23, 1.81), which not significantly higher than predicted (IRR 1.15; 0.90, 1.48). 2021, expected (1.95; 1.65, 2.31 vs. 1.38; 1.13, 1.69 PYs; IRR 1.41; 1.12, 1.77). Although there no significant girls boys (2.16; 1.73, 2.70 PYs) exceeded 1.55; 1.14, 2.12), leading a reversal sex ratio incidence. CONCLUSIONS Germany, 2021. Adolescent more affected this increase, resulting T2D.

Language: Английский

Citations

15

Upstream Determinants of Overweight and Obesity in Europe DOI
Stefanie Vandevijvere, Robby De Pauw, Sanne K. Djojosoeparto

et al.

Current Obesity Reports, Journal Year: 2023, Volume and Issue: 12(4), P. 417 - 428

Published: Aug. 18, 2023

Language: Английский

Citations

15

Neurodevelopmental Programming of Adiposity: Contributions to Obesity Risk DOI Creative Commons
Alicja A. Skowronski, Rudolph L. Leibel, Charles A. LeDuc

et al.

Endocrine Reviews, Journal Year: 2023, Volume and Issue: 45(2), P. 253 - 280

Published: Nov. 16, 2023

This review analyzes the published evidence regarding maternal factors that influence developmental programming of long-term adiposity in humans and animals via central nervous system (CNS). We describe physiological outcomes perinatal underfeeding overfeeding explore potential mechanisms may mediate impact such exposures on development feeding circuits within CNS-including influences metabolic hormones epigenetic changes. The environment, reflective nutritional status, contributes to offspring adiposity. utero early postnatal periods represent critically sensitive windows during which hormonal milieu affects maturation hypothalamus. Maternal hyperglycemia is associated with increased transfer glucose fetus driving fetal hyperinsulinemia. Elevated insulin causes consequently higher circulating leptin concentration. Mechanistic studies animal models indicate important roles peripheral adiposity, suggest optimal concentrations these are critical life. Additionally, environmental be conveyed progeny through marks can potentially vertically transmitted subsequent generations. Thus, metabolic/endocrine signals have lifelong (and possibly multigenerational) impacts body weight regulation.

Language: Английский

Citations

15

A prospective analysis of the long-term impact of the COVID-19 pandemic on well-being and health care among children with a chronic condition and their families: a study protocol of the KICK-COVID study DOI Creative Commons
Petra Warschburger, Clemens Kamrath, Stefanie Lanzinger

et al.

BMC Pediatrics, Journal Year: 2023, Volume and Issue: 23(1)

Published: March 22, 2023

Abstract Background There is consistent evidence that the COVID-19 pandemic associated with an increased psychosocial burden on children and adolescents their parents. Relatively little known about its particular impact high-risk groups chronic physical health conditions (CCs). Therefore, primary aim of study to analyze multiple impacts care well-being these Methods We will implement a two-stage approach. In first step, parents underage from three German patient registries for diabetes, obesity, rheumatic diseases, are invited fill out short questionnaires including questions corona-specific stressors, situation, well-being. next more comprehensive, in-depth online survey carried in smaller subsample. Discussion The provide insights into longer-term stressors during families child CC. simultaneous consideration medical psycho-social endpoints help gain deeper understanding complex interactions affecting family functioning, psychological well-being, delivery. Trial registration Clinical Trials Register (DRKS), no. DRKS00027974. Registered 27th January 2022.

Language: Английский

Citations

12

Back to ‘normal’? BMI, physical fitness and health-related quality of life of children from North East England before, during and after the COVID-19 lockdowns DOI Creative Commons
Laura Basterfield, Brook Galna, Naomi Burn

et al.

Journal of Sports Sciences, Journal Year: 2024, Volume and Issue: 42(8), P. 688 - 700

Published: April 17, 2024

We assessed whether changes in children's body mass index (BMI), physical fitness and health-related quality of life observed post-2020 United Kingdom COVID-19 lockdown remained 12 18 months later. Twenty-metre shuttle run test (20mSRT), handgrip strength, standing broad jump, sit-and-reach, height, mass, (Kidscreen27 questionnaire) were measured 90 children (8–9 years) during October 2019 ("T0"), November 2020 ("T1"), 2021 ("T2") June 2022 ("T3"). Mixed-effects models showed age- sex-normalised BMI increased from T0 (mean: 0.71) to T1 (0.97), remaining elevated at T2 (0.95) T3 (0.89). Decreases 20mSRT performance (22.0) (19.3), then (23.5) (28.3). Standing jump strength over time. The proportion with overweight/obesity (32%) (48%). Health-related decreased for "Physical Wellbeing" yet "Autonomy & Parents". Our findings highlight that lockdowns may have had lasting implications health, the urgent need reduce overweight obesity North East England. Improving health behaviours maximise long-term outcomes build resilience future emergencies disruptions is also paramount.

Language: Английский

Citations

4

Trends in overweight and obesity in Bergen, Norway, using data from routine child healthcare 2010–2022 DOI Creative Commons
Melissa R. Balthasar, Mathieu Roelants,

Bente Brannsether‐Ellingsen

et al.

Acta Paediatrica, Journal Year: 2024, Volume and Issue: 113(9), P. 2098 - 2106

Published: June 19, 2024

Trends in childhood overweight, obesity and severe have been lacking Norway. This study assessed pre-pandemic trends from 2010 to 2019 evaluated differences prevalence during the 2020-2022 pandemic years.

Language: Английский

Citations

4