European Psychiatry,
Journal Year:
2024,
Volume and Issue:
67(1)
Published: Jan. 1, 2024
Abstract
Background
Depressive
symptoms
remaining
after
antidepressant
treatment
increase
the
risk
of
relapse
and
recurrence.
We
aimed
to
analyze
distribution
main
drivers
in
patients
with
a
major
depressive
episode.
Methods
Two
independent
samples
8,229
5,926
from
two
large
naturalistic
studies
were
retrospectively
analyzed.
DSM-IV
criteria
for
episodes
assessed
during
face-to-face
visits
clinicians:
before
prescription
new
antidepressant,
6
weeks
treatment.
The
Hospital
Anxiety
Depression
Scale
(HADS)
was
used
assess
baseline
severity
anxiety
depression.
Results
In
both
samples,
clusters
observed.
first
cluster
encompassed
related
negative
emotional
cognitive
bias
specifically
driven
by
second
neurovegetative
anxiety.
Conclusions
anxiety-depressive
balance
could
be
considered
adapt
treatment,
focusing
on
high
depression,
severity.
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: Feb. 25, 2025
Background:
Comorbidity
of
depression
and
anxiety
is
common
among
adolescents
can
lead
to
adverse
outcomes.
However,
there
limited
understanding
the
latent
characteristics
mechanisms
governing
these
disorders
their
interactions.
Moreover,
few
studies
have
examined
impacts
relevant
risk
protective
factors.
Methods:
This
cross-sectional
study
involved
1,719
students.
Mplus
8.0
software
was
used
conduct
profile
analysis
explore
potential
categories
comorbidities.
R4.3.2
network
core
symptoms,
bridge
disorders,
evaluate
effects
Results:
Three
were
established:
"healthy"
(57.8%),
"mild
depression-mild
anxiety"
(36.6%),
"moderately
severe
depression-moderate
(5.6%).
"Depressed
mood",
"nervousness",
"difficulty
relaxing"
symptoms
in
both
depression-anxiety
comorbidity
Stress
perception
neuroticism
serve
as
bridging
nodes
connecting
some
are
thus
considered
most
prominent
Conclusions:
According
identified
this
study,
targeted
intervention
treatment
be
provided
groups
with
comorbid
anxiety,
thereby
reducing
comorbidities
adolescents.
BACKGROUND
Generative
Conversational
AI
(GCAI)
holds
significant
potential
within
the
mental
health
domain,
particularly
for
adolescents
in
impoverished
regions,
as
these
areas
often
lack
adequate
resources
and
infrastructure.
OBJECTIVE
To
evaluate
prevalence
of
childhood
trauma,
issues,
needs
GCAI
among
from
to
explore
addressing
needs.
METHODS
An
online
survey
was
conducted
18,093
regions.
Machine
learning
ensembles,
network
analysis,
Bayesian
networks
were
used
identify
key
predictors
underlying
relationships
between
health,
RESULTS
The
analysis
revealed
that
issues
15.65%
(95%
CI:
15.12%-16.18%),
38.12%
37.41%-38.83%).
findings
underscore
address
areas,
emphasizing
importance
targeting
depression,
anxiety,
interpersonal
sensitivity
mitigate
effects
trauma
other
issues.
Mental
prevalent
15.12%-16.18%)
adolescents,
with
12.94%
12.46%-13.43%)
exhibiting
mild
2.71%
moderate
severe
Childhood
reported
by
34.46%
33.76%-35.15%)
participants.
expressed
37.41%-38.83%)
75.18%
73.58%-76.77%)
those
43.70%
42.46%-44.93%)
indicating
a
need
support.
models
identified
14
needs,
integrating
glmBoost
RF
algorithms
showing
highest
predictive
accuracy
training
set
(AUC
=
.982)
testing
.759).
Network
depression
(EI
1.15)
anxiety
1.06)
core
nodes,
emotional
abuse
(BEI
1.69)
1.61)
bridge
nodes.
instability
(strength
-38.74,
direction
0.88),
-25.41,
0.91),
-18.21,
0.92)
direct
causal
CONCLUSIONS
study
highlights
regions
sensitivity.
Future
work
should
focus
on
developing
culturally
appropriate
interventions
provide
accessible
psychological
support
areas.
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: March 27, 2025
Interpersonal
needs
and
depression
are
two
recognized
significant
risk
factors
for
suicidal
ideation.
Previous
studies
have
preliminarily
revealed
the
gender-dependent
effects
of
interpersonal
on
However,
there
very
few
that
place
these
variables
within
a
single
framework
apply
symptom-level
analysis
to
investigate
relationships
among
them.
This
study
applied
network
construct
female
male
networks
using
data
from
781
628
young
adults.
The
included
needs,
depressive
symptoms,
Key
characteristics
networks,
including
edge
connections,
bridge
expected
influence
(BEI),
global
(GEI),
were
compared.
results
suggested
gender
significantly
impacts
node
BEI,
GEI
final
networks.
Several
connections
disclosed,
such
as
perceived
burdensomeness
(PB)-suicidal
ideation,
hopelessness-suicidal
PB-sense
failure,
PB-sadness.
PB
(marginally)
thwarted
belongingness
show
differences
in
their
impact
symptoms.
is
greater
than
network.
These
findings
offer
valuable
insights
modern
theoretical
frameworks
examining
between
Additionally,
provide
empirical
support
selecting
screening,
prevention,
intervention
strategies
ideation
across
genders.
Psychology Research and Behavior Management,
Journal Year:
2024,
Volume and Issue:
Volume 17, P. 4399 - 4412
Published: Dec. 1, 2024
Network
analysis
is
a
statistical
method
that
explores
the
complex
interrelationships
among
variables
by
representing
them
as
nodes
and
edges
in
network
structure.
This
study
aimed
to
examine
interconnections
between
family
functioning,
anxiety,
depression
vocational
school
students
through
approach.
Frontiers in Psychiatry,
Journal Year:
2024,
Volume and Issue:
15
Published: Aug. 21, 2024
Introduction
With
the
rising
demand
for
medical
services
and
associated
burden,
work-related
stress
mental
health
issue
have
garnered
increased
attention
among
healthcare
workers.
Anxiety,
cognitive
impairment,
their
comorbidities
severely
impact
physical
as
well
work
status
of
The
network
analysis
method
was
used
to
identify
anxiety
impairment
workers
using
Generalized
Anxiety
Disorder
Scale
(GAD-7)
Perceived
Deficit
Questionnaire
Depression
(PDQ-D).
We
sought
core
symptoms
with
comorbidity
in
Methods
study
conducted
by
Shandong
Daizhuang
Hospital
Qingdao
Mental
Health
Center
China
from
September
13,
2022,
October
25,
involving
a
total
680
participants.
GAD-7
PDQ-D
were
utilized
assess
respectively.
Regularized
partial
correlation
employed
examing
expected
influence
predictability
each
item
within
network.
Statistical
visualization
performed
R
software.
Results
mean
score
3.25,
while
15.89.
PDQ17
“Remembering
numbers”,
PDQ12
“Trouble
get
started”
PDQ20
make
decisions”
emerged
central
anxiety-cognition
GAD6
“Irritable”,
GAD5
“Restlessness”
GAD1
“Nervousness
or
anxiety”
identified
most
critical
bridge
connecting
cognition.
Gender
found
be
unrelated
global
strength
network,
edge
weight
distribution,
individual
weights.
Conclusion
Utilizing
(i.e.,
Remembering
numbers,
Trouble
started,
decisions,
Irritable,
Restlessness
Nervousness
anxiety)
primary
intervention
points
may
aid
mitigating
serious
consequences
anxiety,
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 16, 2024
AbstractBackground
Comorbidity
of
depression
and
anxiety
is
common
among
adolescents
can
lead
to
adverse
outcomes.
However,
there
limited
understanding
the
latent
characteristics
mechanisms
governing
these
disorders
their
interactions.
Moreover,
few
studies
have
examined
impacts
relevant
risk
protective
factors.
Methods
This
cross-sectional
study
involved
1,719
students.
Mplus
8.0
software
was
used
conduct
profile
analysis
explore
potential
categories
comorbidities.
R4.3.2
network
core
symptoms,
bridge
disorders,
evaluate
effects
Results
Three
were
established:
“healthy”
(57.8%),
“mild
depression-mild
anxiety”
(36.6%),
“moderately
severe
depression-moderate
(5.6%).
“Depressed
mood”,
“nervousness”,
"difficulty
relaxing"
symptoms
in
both
depression-anxiety
comorbidity
Stress
perception
neuroticism
serve
as
bridging
nodes
connecting
some
are
thus
considered
most
prominent
Conclusions
According
identified
this
study,
targeted
intervention
treatment
be
provided
groups
with
comorbid
anxiety,
thereby
reducing
comorbidities
adolescents.
Depression and Anxiety,
Journal Year:
2024,
Volume and Issue:
2024(1)
Published: Jan. 1, 2024
Background:
Depression
and
anxiety
are
among
the
most
prevalent
psychiatric
disorders
worldwide,
affecting
individuals
of
all
ages.
The
co-occurrence
these
often
exacerbates
their
negative
health
impacts,
underscoring
necessity
understanding
comorbid
mechanisms.
Methods:
This
study
employed
cross-lagged
panel
networks
(CLPNs)
to
explore
longitudinal
associations
between
depression
symptoms
across
three
age
groups
compare
respective
symptom
networks.
CLPNs
were
constructed
through
cross-temporal
different
symptoms,
reflecting
both
pattern
interaction
significance
specific
in
comorbidity.
sample
consisted
1258
adolescents
(aged
13-19
years,
M
=
15.98),
1118
college
students
17-24
19.94),
548
older
adults
60-101
85.19)
from
China.
assessed
using
subscales
Depression,
Anxiety,
Stress
Scale
Short
Version
(DASS-21)
at
two
time
points
over
a
6-month
period
during
2020-2021.
Results:
findings
revealed
that
prevalence
adolescents,
students,
was
25.9%/46.6%,
53.7%/61.5%,
7.2%/22.5%,
respectively.
network
structure
varied
groups:
exhibiting
tight
interconnection
while
showed
stronger
small-world
characteristics.
A
key
finding
central
role
irrational
fear.
In
addition,
somatic
frequently
emerged
as
outcomes
other
psychological
symptoms.
Conclusion:
more
pronounced
compared
adults.
Comparisons
overall
provide
insights
into
lifelong
trajectories
centrality
fears
somatization
is
emphasized.
These
results
offer
guidance
for
targeted
clinical
interventions.