Lifetime influences on imaging markers of adverse brain health and vascular disease DOI Creative Commons
Ellen V. Backhouse, Sarah Bauermeister, Joanna M. Wardlaw

et al.

Cerebral Circulation - Cognition and Behavior, Journal Year: 2023, Volume and Issue: 6, P. 100194 - 100194

Published: Dec. 15, 2023

Cerebral small vessel disease (cSVD) is highly prevalent in the general population, increases with age and vascular risk factor exposure, a common cause of stroke dementia. There great variation cSVD burden experienced older age, maintaining brain health across life course requires looking beyond an individual's current clinical status traditional factors. Of particular importance are social determinants which can be more important than healthcare or lifestyle choices influencing later outcomes, including health. In this paper we discuss cerebrovascular disease, focusing on impact socioeconomic markers cSVD. We outline potential mechanisms behind these associations, early exposures, behaviours reserve maintenance, highlight public interventions to address key factors for from stages.

Language: Английский

Neurosustainability DOI Creative Commons
M. Khalil

Frontiers in Human Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: Aug. 29, 2024

While the human brain has evolved extraordinary abilities to dominate nature, modern living paradoxically trapped it in a contemporary "cage" that stifles neuroplasticity. Within this environment lurk unseen natural laws with power sustain brain's adaptive capacities - if consciously orchestrated into environments we design. For too long our have imposed an unyielding static state, while still neglecting constant nature as evolves world increasing sophistication. The theory introduced article aims go back without having time, introducing and expounding Neurosustainability novel paradigm seeing beyond confines architect brains parallel. Its integrated neuro-evidenced framework proposes four enrichment scopes-spatial, natural, aesthetic, social-each holding multifaceted attributes promising regions like hippocampus, cortex amygdala. liberate quintessential essence of enhance neuroplastic processes through cycle begins design extends epigenetic changes. This shift foster cognitive health wellness by addressing issues stress, depression, anxiety decline common era thereby offering path toward more neurosustainable aiming nurture evolution now beyond.

Language: Английский

Citations

7

Brain health is a human right: Implications for policy and research DOI Creative Commons
Timothy Daly

Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Highlights•Promotion of brain health across the lifetime is both urgent and under-prioritized.•Recognizing as a human right should improve promotion.•A rights-based approach to policy research emphasizes need for population-level interventions studies part public health.AbstractThe call synergize with mental has major ramifications policy. Mental been recognized universal right, but no such declaration exists health. Here, I defend lifelong derived, intermediary, generative right. It derived from physical because it reducible facts about body. This grounds in health, long-standing hard legal status, while avoiding "rights inflation." intermediary bridges gap between since an organ that central provides impetus downstream actions including creation health-based "neurorights" bolstering healthy environment protect collective cognitive Thus, would guarantee citizens live grow health-promoting environment. A also important consequences research. help move away disease paradigm focuses on individual risk responsibility study deeper contributions through population neuroscience Until alongside their synergy will remain incomplete, promotion lack unity.

Language: Английский

Citations

0

Mental health and psychological processes associated with cognitive aging and dementia DOI
David Bartrés‐Faz, Natalie L. Marchant

Current Opinion in Neurology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 7, 2025

Purpose of review This focuses on the role psychological factors in cognitive aging and dementia, an area that has received less attention compared to other modifiable (e.g. sleep, physical activity, so on) or reduction disease risk. Recent findings A range mental health aspects, including clinical symptoms, stable personality traits, more specific constructs processes repetitive negative thinking, purpose life), are associated with dementia Psychological can either serve as protective risk elements, influencing brain through general mechanisms, stress regulation impact several biological systems, well modulate resistance resilience Alzheimer's age-related changes. Protective traits linked healthier lifestyle habits, while behaviors, may function across lifespan, suggesting benefits for education from early life. Summary The emphasizes need greater focus optimizing being, particularly at-risk populations, suggests interventions should be tailored individuals’ values life purposes. Additionally, further research is needed explore neurobiological mechanisms which psychologically focused influence decline dementia.

Language: Английский

Citations

0

Lifetime influences on imaging markers of adverse brain health and vascular disease DOI Creative Commons
Ellen V. Backhouse, Sarah Bauermeister, Joanna M. Wardlaw

et al.

Cerebral Circulation - Cognition and Behavior, Journal Year: 2023, Volume and Issue: 6, P. 100194 - 100194

Published: Dec. 15, 2023

Cerebral small vessel disease (cSVD) is highly prevalent in the general population, increases with age and vascular risk factor exposure, a common cause of stroke dementia. There great variation cSVD burden experienced older age, maintaining brain health across life course requires looking beyond an individual's current clinical status traditional factors. Of particular importance are social determinants which can be more important than healthcare or lifestyle choices influencing later outcomes, including health. In this paper we discuss cerebrovascular disease, focusing on impact socioeconomic markers cSVD. We outline potential mechanisms behind these associations, early exposures, behaviours reserve maintenance, highlight public interventions to address key factors for from stages.

Language: Английский

Citations

1