The role of innate immune cells in modulating vascular dynamics in skin malignancies

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Journal Year: 2025, Volume and Issue: unknown, P. 189331 - 189331

Published: April 1, 2025

A developing tumor relies heavily on blood vessels to supply oxygen and nutrients. As a result, angiogenesis, the formation of new vessels, supports growth progression. Similarly, lymphangiogenesis, lymphatic plays critical role in metastatic dissemination by providing pathways for malignant cells spread. The microenvironment is crucial establishing maintaining these vascular networks, with innate immune playing key regulatory role. Notably, are specifically enriched barrier tissues, such as skin, emphasizing their importance skin malignancies Therefore, understanding regulating angiogenesis lymphangiogenesis essential novel therapeutic strategies. This review article explores how influence vasculature highlights potential that may arise from this knowledge.

Language: Английский

Advances and challenges in CAR-T cell therapy for head and neck squamous cell carcinoma

Biomarker Research, Journal Year: 2025, Volume and Issue: 13(1)

Published: May 1, 2025

Language: Английский