Discover Oncology,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Dec. 18, 2024
Palmitoylation,
a
key
post-translational
modification,
plays
significant
role
in
ovarian
cancer
(OV)
progression.
However,
the
impact
of
palmitoylation-related
genes
on
genomic
instability,
immune
infiltration,
and
therapeutic
response
OV
remains
poorly
understood.
This
study
aimed
to
investigate
these
factors
facilitate
risk
stratification
intervention,
providing
insights
into
personalized
treatment
strategies.
Frontiers in Cell and Developmental Biology,
Journal Year:
2024,
Volume and Issue:
12
Published: Nov. 5, 2024
S-Palmitoylation
has
been
widely
noticed
and
studied
in
a
variety
of
diseases.
Increasing
evidence
suggests
that
S-palmitoylation
modification
also
plays
key
role
Glioblastoma
(GBM).
The
zDHHC
family,
as
an
important
member
S-palmitoyltransferases,
received
extensive
attention
for
its
function
mechanism
GBM
which
is
one
the
most
common
primary
malignant
tumors
brain
adverse
prognosis.
This
review
focuses
on
essential
their
involvement
GBM.
By
summarizing
recent
studies
molecules
GBM,
we
highlight
significance
regulating
critical
processes
such
cell
proliferation,
invasion,
apoptosis.
Specifically,
members
zDHHC3,
zDHHC4,
zDHHC5
others
affect
signal
transduction
phenotypic
transformation
cells
through
different
pathways,
turn
influence
tumorigenesis
progression.
systematically
outlines
family-mediated
emphasizes
importance
development
this
disease,
provides
potential
targets
strategies
treatment
It
offers
theoretical
foundations
insights
future
research
clinical
applications.
