Prognostic Value of the Number of Circulating Tumor Cells in Patients with Metastatic Non-Small Cell Lung Cancer

Micromachines, Journal Year: 2025, Volume and Issue: 16(4), P. 470 - 470

Published: April 15, 2025

Investigating the molecular and genetic characteristics of circulating tumor cells (CTCs) presents a promising approach for personalizing treatment in patients with malignant neoplasms, given limitations traditional biopsy histopathology. This study aimed to isolate, characterize, analyze CTC dynamics peripheral blood 30 metastatic lung cancer develop criteria response prognosis. We detected CTCs before start monitored changes during treatment, correlating these responses evaluated by standard imaging methods. A decrease course therapy was linked favorable response, while stable counts indicated lack poor survival The OS analyzed compared initial number samples. significant reductions median were evident >3 total at baseline those ≤3 (median 26 months, n = 10, vs. 8 19, respectively HR 2.6, 95% CI 1.07 6.4).

Language: Английский

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DNA network-enhanced electrochemical cytosensor for analyzing mesenchymal CTCs and epithelial-mesenchymal transition in ovarian cancer

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162728 - 162728

Published: April 1, 2025

Language: Английский

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Lung-specific metastasis: the coevolution of tumor cells and lung microenvironment

Molecular Cancer, Journal Year: 2025, Volume and Issue: 24(1)

Published: April 16, 2025

Language: Английский

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Single Circulating Tumor Cell Sequencing Based on Improved High-Porosity Membranes And Nanoporous Microchambers

Published: Jan. 1, 2024

Language: Английский

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Liquid biopsy biomarkers in breast cancer: An overview of systematic reviews

Clinica Chimica Acta, Journal Year: 2024, Volume and Issue: 566, P. 120063 - 120063

Published: Nov. 29, 2024

Language: Английский

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