The protective role of 3-Indoleglyoxylic acid in Bisphenol S-induced intestinal barrier dysfunction via mitochondrial ROS-Mediated IL-17/CXCL10/TNF-α signaling DOI Creative Commons
Hongbin Wang,

Guolei Niu,

Hai-xing Mai

et al.

Environment International, Journal Year: 2025, Volume and Issue: unknown, P. 109477 - 109477

Published: April 1, 2025

Language: Английский

Intervening with nanozymes in aging-related diseases: Strategies for restoring mitochondrial function DOI
Fanyong Yan, Dongyang Liu,

Baoshan Zhao

et al.

Biomaterials Advances, Journal Year: 2025, Volume and Issue: 169, P. 214193 - 214193

Published: Jan. 18, 2025

Language: Английский

Citations

2

Synergy of a Complimentary Ionic Biogel Network for Through-Hair Neurohaptics DOI Creative Commons
Huanyu Cheng, Ankan Dutta, Md Abu Sayeed Biswas

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

Abstract Understanding the neural mechanisms underlying haptic sensations is crucial for advancing neuroprosthetics. However, achieving on-site amplification non-invasively through-hair recordings remains a significant challenge as it requires thermoreversible, bioadhesive, and semiconducting characteristics in same material. Typical polymer composite compromises on complementary properties. To address this, we present membraneless organelles - inspired ionic biogel that leverages liquid–liquid phase separation. This enables unique synergy of properties, including rapid thermoreversible transitions, p-type semiconductivity, thermoelectricity, enhanced electrochemical stability, self-healing, bioadhesive capabilities. These enable to analyze frequency dependence event-related desynchronization during electrical stimulation over days mimicking response mechanoreceptors sensation. thermoresponsive, also phase-reversible, self-balancing, tip-shaped vertical organic transistor with high transconductance 44 mS at 40°C. The demonstrates synergistic properties understand neurohaptics.

Language: Английский

Citations

0

An Overview of Liquid-Liquid Phase Separation and Its Mechanisms in Sepsis DOI Creative Commons
Meiling Cao, Xinyi Zhang, Xiaohan Wang

et al.

Journal of Inflammation Research, Journal Year: 2025, Volume and Issue: Volume 18, P. 3969 - 3980

Published: March 1, 2025

Sepsis is a systemic inflammatory response syndrome triggered by the invasion of bacteria or pathogenic microorganisms into human body, which may lead to variety serious complications and pose threat patient's life health. Liquid-liquid phase separation (LLPS) biomolecular process in different biomolecules, such as proteins nucleic acids, form liquid condensates through interactions, these play key roles cellular physiological processes. LLPS affect development sepsis several pathways, modulation factors, immune responses, cell death, altering function activity which, turn, infection inflammation. In this paper, we first discuss mechanism separation, then summarize studies sepsis, finally propose potential application treatment strategies, while pointing out limitations existing directions for future research.

Language: Английский

Citations

0

Crosstalk Between Phase-Separated Membraneless Condensates and Membrane-Bound Organelles in Cellular Function and Disease DOI

Aydan Torun,

Hoşnaz Tuğral,

Sreeparna Banerjee

et al.

Advances in experimental medicine and biology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0

Regulation and function of inosine monophosphate dehydrogenase 2 cytoophidia during mouse and human decidualization DOI
Yu‐Ying He, Dandan Jin, Bo Li

et al.

Cellular Signalling, Journal Year: 2025, Volume and Issue: unknown, P. 111795 - 111795

Published: April 1, 2025

Language: Английский

Citations

0

The protective role of 3-Indoleglyoxylic acid in Bisphenol S-induced intestinal barrier dysfunction via mitochondrial ROS-Mediated IL-17/CXCL10/TNF-α signaling DOI Creative Commons
Hongbin Wang,

Guolei Niu,

Hai-xing Mai

et al.

Environment International, Journal Year: 2025, Volume and Issue: unknown, P. 109477 - 109477

Published: April 1, 2025

Language: Английский

Citations

0