Reliability of Brain Localization Using Task-based fMRI for Late-life Depression with Suicidal Risk DOI
Ai‐Ling Hsu, Changwei W. Wu, Chih‐Mao Huang

et al.

Journal of Psychiatric Research, Journal Year: 2025, Volume and Issue: 187, P. 10 - 17

Published: April 29, 2025

Language: Английский

Psilocybin therapy for mood dysfunction in Parkinson’s disease: an open-label pilot trial DOI Creative Commons
Ellen Bradley,

Kimberly Sakai,

Gisele Fernandes‐Osterhold

et al.

Neuropsychopharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: April 9, 2025

Language: Английский

Citations

0
Depressive symptoms partially mediate the relationship between psychosocial factors and epigenetic age acceleration in a multi-racial/ethnic sample of older adults DOI Creative Commons

Lauren Opsasnick,

Wei Zhao, Lauren Schmitz

et al.

Brain Behavior & Immunity - Health, Journal Year: 2025, Volume and Issue: 45, P. 100994 - 100994

Published: April 13, 2025

Psychosocial factors, including cumulative psychosocial stress and loneliness, have been linked to epigenetic aging in older adults. Further, depressive symptoms established relationships with both factors aging. However, it is not known whether mediate the association between aging.We conducted linear regression models examine associations stress, five age acceleration (AA) measures estimated by DNA methylation a multi-racial/ethnic sample of 2681 adults from Health Retirement Study (mean age: 70.4 years). For all identified associations, we tested for effect modification sex educational attainment performed mediation analysis characterize role on these associations.Psychosocial were each associated at least one measure AA (FDR q < 0.05). observed interactions DunedinPACE, as well loneliness GrimAA, PhenoAA, females individuals without college degree appearing more sensitive effects Depressive mediated 24 % 35 HannumAA, 40 37 GrimAA respectively. this study may help elucidate relationship aging, which critical understanding biological mechanisms through contribute age-related disease.

Language: Английский

Citations

0
Estradiol, via estrogen receptor β signaling, mediates stress-susceptibility in the male brain DOI
Polymnia Georgiou, Abagail F. Postle,

Ta-Chung M. Mou

et al.

Molecular Psychiatry, Journal Year: 2025, Volume and Issue: unknown

Published: April 24, 2025

Language: Английский

Citations

0
White matter hyperintensities and relapse risk in late-life depression DOI Creative Commons
Leigh B. Pearcy, Helmet T. Karim, Meryl A. Butters

et al.

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Reliability of Brain Localization Using Task-based fMRI for Late-life Depression with Suicidal Risk DOI
Ai‐Ling Hsu, Changwei W. Wu, Chih‐Mao Huang

et al.

Journal of Psychiatric Research, Journal Year: 2025, Volume and Issue: 187, P. 10 - 17

Published: April 29, 2025

Language: Английский

Citations

0