The Impact of Atlas Parcellation on Functional Connectivity Analysis Across Six Psychiatric Disorders DOI Creative Commons

Xiaoya Wu,

Chuang Liang,

Juan Bustillo

et al.

Human Brain Mapping, Journal Year: 2025, Volume and Issue: 46(5)

Published: April 1, 2025

Neuropsychiatric disorders are associated with altered functional connectivity (FC); however, the reported regional patterns of alterations suffered from low replicability and high variability. This is partly because differences in atlas delineation techniques used to measure FC-related deficits within/across disorders. We systematically investigated impact brain parcellation approach on FC-based network analysis. focused identifying replicable FCs using three structural atlases, including Automated Anatomical Labeling (AAL), Brainnetome (BNA) HCP_MMP_1.0, four approaches: Yeo-Networks (Yeo), Gordon parcel (Gordon) two Schaefer parcelletions, among correlation, group difference, classification tasks six neuropsychiatric disorders: attention deficit hyperactivity disorder (ADHD, n = 340), autism spectrum (ASD, 513), schizophrenia (SZ, 200), schizoaffective (SAD, 142), bipolar (BP, 172), major depression (MDD, 282). Our cross-atlas/disorder analyses demonstrated that frontal-related FC were reproducible all disorders, independent atlasing approach; extraction other areas accuracy affected by schema. Overall, atlases finer granularity performed better tasks. Specifically, generated most repeatable across illnesses. These results indicate may serve as potential common robust neuro-abnormalities 6 psychiatric Furthermore, order improve rsfMRI-based analyses, this study suggests use templates at larger granularity.

Language: Английский

Application of Neuroimaging Techniques in the Research and Treatment of Alcohol Use Disorder DOI

光平 苏

Advances in Clinical Medicine, Journal Year: 2025, Volume and Issue: 15(03), P. 1807 - 1816

Published: Jan. 1, 2025

Language: Английский

Citations

0
The Impact of Atlas Parcellation on Functional Connectivity Analysis Across Six Psychiatric Disorders DOI Creative Commons

Xiaoya Wu,

Chuang Liang,

Juan Bustillo

et al.

Human Brain Mapping, Journal Year: 2025, Volume and Issue: 46(5)

Published: April 1, 2025

Neuropsychiatric disorders are associated with altered functional connectivity (FC); however, the reported regional patterns of alterations suffered from low replicability and high variability. This is partly because differences in atlas delineation techniques used to measure FC-related deficits within/across disorders. We systematically investigated impact brain parcellation approach on FC-based network analysis. focused identifying replicable FCs using three structural atlases, including Automated Anatomical Labeling (AAL), Brainnetome (BNA) HCP_MMP_1.0, four approaches: Yeo-Networks (Yeo), Gordon parcel (Gordon) two Schaefer parcelletions, among correlation, group difference, classification tasks six neuropsychiatric disorders: attention deficit hyperactivity disorder (ADHD, n = 340), autism spectrum (ASD, 513), schizophrenia (SZ, 200), schizoaffective (SAD, 142), bipolar (BP, 172), major depression (MDD, 282). Our cross-atlas/disorder analyses demonstrated that frontal-related FC were reproducible all disorders, independent atlasing approach; extraction other areas accuracy affected by schema. Overall, atlases finer granularity performed better tasks. Specifically, generated most repeatable across illnesses. These results indicate may serve as potential common robust neuro-abnormalities 6 psychiatric Furthermore, order improve rsfMRI-based analyses, this study suggests use templates at larger granularity.

Language: Английский

Citations

0