Preclinical in vitro models of HNSCC and their role in drug discovery - an emphasis on the cancer microenvironment and microbiota DOI Creative Commons
Anne‐Sophie Becker, Sonja Oehmcke-Hecht,

Erik Dargel

et al.

Expert Opinion on Drug Discovery, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 21

Published: Dec. 15, 2024

Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer worldwide. Treatment options patient outcomes have not improved significantly over past decades, increasing need for better preclinical models. Holistic approaches that include an intact functional immune compartment along with patient's individual tumor microbiome will help improve predictive value of novel drug efficacy.

Language: Английский

Impact of oral flora in tongue coating and saliva on oral cancer risk and the regulatory role of Interleukin-8 DOI
Xuemin Wang,

Xiaona Song,

Jiping Gao

et al.

Cytokine, Journal Year: 2024, Volume and Issue: 185, P. 156821 - 156821

Published: Dec. 3, 2024

Language: Английский

Citations

1
Preclinical in vitro models of HNSCC and their role in drug discovery - an emphasis on the cancer microenvironment and microbiota DOI Creative Commons
Anne‐Sophie Becker, Sonja Oehmcke-Hecht,

Erik Dargel

et al.

Expert Opinion on Drug Discovery, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 21

Published: Dec. 15, 2024

Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer worldwide. Treatment options patient outcomes have not improved significantly over past decades, increasing need for better preclinical models. Holistic approaches that include an intact functional immune compartment along with patient's individual tumor microbiome will help improve predictive value of novel drug efficacy.

Language: Английский

Citations

0