Encephalitis following COVID-19 Vaccination: A Systematic Review DOI Creative Commons
Mariam Abdelhady, Muhammad Ashraf Husain, Yousef Hawas

et al.

Vaccines, Journal Year: 2023, Volume and Issue: 11(3), P. 576 - 576

Published: March 2, 2023

Background: Since the advent of global COVID-19 vaccination, several studies reported cases encephalitis with its various subtypes following vaccinations. In this regard, we conducted a systematic review to investigate and characterize clinical settings these aid in physician awareness proper care provision. Methods: We systematically searched PubMed, Web Science, Scopus manually Google Scholar. Studies published until October 2022 were included. Demographic data, features, vaccine treatment lines, outcomes extracted. Results: A total 65 patients from 52 The mean age was 46.82 ± 19.25 years, 36 (55.4%) males. AstraZeneca most-reported associated (38.5%) followed by Pfizer (33.8%), Moderna (16.9%), others. Moat occurred after first dose vaccination 41/65 (66.1%). time between symptom onset 9.97 7.16 days. Corticosteroids (86.2 %) immunosuppressants (81.5 most used lines treatment. majority affected individuals experienced full recovery. Conclusion: Our study summarizes current evidence post-vaccination encephalitis, regarding presentation, symptoms onset, management, outcomes, comorbid conditions; however, it fails either acknowledge incidence occurrence or establish causal relationship vaccines encephalitis.

Language: Английский

A survey of COVID-19 vaccine acceptance across 23 countries in 2022 DOI Open Access
Jeffrey V. Lazarus, Katarzyna Wyka, Trenton M. White

et al.

Nature Medicine, Journal Year: 2023, Volume and Issue: 29(2), P. 366 - 375

Published: Jan. 9, 2023

Language: Английский

Citations

287
A multinational Delphi consensus to end the COVID-19 public health threat DOI Creative Commons
Jeffrey V. Lazarus, Diana Romero, Christopher J. Kopka

et al.

Nature, Journal Year: 2022, Volume and Issue: 611(7935), P. 332 - 345

Published: Nov. 3, 2022

Abstract Despite notable scientific and medical advances, broader political, socioeconomic behavioural factors continue to undercut the response COVID-19 pandemic 1,2 . Here we convened, as part of this Delphi study, a diverse, multidisciplinary panel 386 academic, health, non-governmental organization, government other experts in from 112 countries territories recommend specific actions end persistent global threat public health. The developed set 41 consensus statements 57 recommendations governments, health systems, industry key stakeholders across six domains: communication; systems; vaccination; prevention; treatment care; inequities. In wake nearly three years fragmented national responses, it is instructive note that highest-ranked call for adoption whole-of-society whole-of-government approaches 1 , while maintaining proven prevention measures using vaccines-plus approach 2 employs range financial support complement vaccination. Other with at least 99% combined agreement advise governments improve communication, rebuild trust engage communities 3 management responses. findings which have been further endorsed by 184 organizations globally, include points unanimous agreement, well >5% disagreement, provide social policy address inadequacies help bring an end.

Language: Английский

Citations

176
Determinants of COVID-19 vaccination status and hesitancy among older adults in China DOI Open Access

Gewei Wang,

Yao Yao, Yafeng Wang

et al.

Nature Medicine, Journal Year: 2023, Volume and Issue: 29(3), P. 623 - 631

Published: Jan. 31, 2023

Language: Английский

Citations

85
Vaccine Hesitancy: Obstacles and Challenges DOI Open Access
Preeti M. Galagali, Aarti Kinikar, Vikram Sakaleshpur Kumar

et al.

Current Pediatrics Reports, Journal Year: 2022, Volume and Issue: 10(4), P. 241 - 248

Published: Oct. 8, 2022

Language: Английский

Citations

83
Influence of COVID-19 on trust in routine immunization, health information sources and pandemic preparedness in 23 countries in 2023 DOI Creative Commons
Jeffrey V. Lazarus, Trenton M. White, Katarzyna Wyka

et al.

Nature Medicine, Journal Year: 2024, Volume and Issue: 30(6), P. 1559 - 1563

Published: April 29, 2024

Abstract It is unclear how great a challenge pandemic and vaccine fatigue present to public health. We assessed perspectives on coronavirus disease 2019 (COVID-19) routine immunization as well trust in information sources future preparedness survey of 23,000 adults 23 countries October 2023. The participants reported lower intent get COVID-19 booster 2023 (71.6%), compared with 2022 (87.9%). A total 60.8% expressed being more willing vaccinated for diseases other than result their experience during the pandemic, while 23.1% less willing. Trust 11 selected each averaged 7 10-point scale one’s own doctor or nurse World Health Organization, averaging 6.9 6.5, respectively. Our findings emphasize that hesitancy challenges remain health practitioners, underscoring need targeted, culturally sensitive communication strategies.

Language: Английский

Citations

27
The Role of Faith-Based Organizations in Improving Vaccination Confidence & Addressing Vaccination Disparities to Help Improve Vaccine Uptake: A Systematic Review DOI Creative Commons
Uzma Syed, Olivia Kapera,

Aparajita Chandrasekhar

et al.

Vaccines, Journal Year: 2023, Volume and Issue: 11(2), P. 449 - 449

Published: Feb. 15, 2023

The COVID-19 pandemic underscored the importance of vaccination to support individual health across life-course, with playing a central strategy role in mitigating transmission and disease. This required unprecedented mobilization coordination all sectors meet people where they are, enable equitable access, build confidence. A literature search was conducted combinations keywords variations faith-based organizations (FBOs). Search inclusion criteria were: (1) FBO programs that supported public emergency efforts, including efforts as primary outcome; (2) articles written English language. total 37 met (n = 26 focused on general campaigns, n 11 efforts). findings related campaigns fell into four themes: FBO’s ability tailor campaigns; mitigate barriers; (3) establish trust; (4) disseminate sustain efforts. vaccine uptake three pre-pandemic influenza HPV addressing disparities minority communities, enabling vaccination. review demonstrated FBOs have vital both initiatives high

Language: Английский

Citations

34
Nationwide health, socio-economic and genetic predictors of COVID-19 vaccination status in Finland DOI Creative Commons
Tuomo Hartonen, Bradley Jermy,

Hanna Sõnajalg

et al.

Nature Human Behaviour, Journal Year: 2023, Volume and Issue: 7(7), P. 1069 - 1083

Published: April 20, 2023

Abstract Understanding factors associated with COVID-19 vaccination can highlight issues in public health systems. Using machine learning, we considered the effects of 2,890 health, socio-economic and demographic entire Finnish population aged 30–80 genome-wide information from 273,765 individuals. The strongest predictors status were labour income medication purchase history. Mental conditions having unvaccinated first-degree relatives reduced vaccination. A prediction model combining all achieved good discrimination (area under receiver operating characteristic curve, 0.801; 95% confidence interval, 0.799–0.803). 1% individuals highest predicted risk not vaccinating had an observed rate 18.8%, compared 90.3% study population. We identified eight genetic loci uptake derived a polygenic score, which was weak predictor independent subset. Our results suggest that at higher suffering worst consequences are also less likely to vaccinate.

Language: Английский

Citations

31
Recent trends in vaccine coverage and confidence: A cause for concern DOI Creative Commons
Rachel L Eagan, Heidi J. Larson, Alexandre de Figueiredo

et al.

Human Vaccines & Immunotherapeutics, Journal Year: 2023, Volume and Issue: 19(2)

Published: Aug. 1, 2023

Declining trends in vaccine confidence come at a time when routine immunization coverage for children has slumped to decades-long low. With some of the largest losses experienced among young adults, this is concerning trend with potential long-term implications. This article reflects on recent research examining levels and over across globe, drivers influencing confidence, role COVID-19 pandemic shaping today. Timely examination causes consequences waning critical evaluation response measures will prove vital mitigating additional uptake while contributing building resilience face future health crises.

Language: Английский

Citations

28
Social and structural determinants of COVID-19 vaccine uptake among racial and ethnic groups DOI Open Access
Juan M. Peña, Matthew Schwartz, Alexandra Hernandez‐Vallant

et al.

Journal of Behavioral Medicine, Journal Year: 2023, Volume and Issue: 46(1-2), P. 129 - 139

Published: Jan. 18, 2023

Language: Английский

Citations

27
Global burden of vaccine‐associated anaphylaxis and their related vaccines, 1967–2023: A comprehensive analysis of the international pharmacovigilance database DOI Open Access

K. K. Lee,

Hayeon Lee, Rosie Kwon

et al.

Allergy, Journal Year: 2023, Volume and Issue: 79(3), P. 690 - 701

Published: Dec. 10, 2023

Abstract Background Vaccine‐associated anaphylaxis is a rare but life‐threatening reaction that occurs within minutes to hours of exposure allergens. As studies utilizing large‐scale data investigate this topic are limited, further research needed assess its burden, long‐term trends, and associated risk factors so as gain comprehensive understanding vaccine‐associated globally. Therefore, study aimed the global burden related vaccines. Method This utilized World Health Organization International Pharmacovigilance Database, in which reports between 1967 2023 were obtained (total = 131,255,418). We estimated reporting counts, reported odds ratio (ROR), information component (IC) identify relationship 19 vaccines 156 countries territories. Results identified 31,676 among 363,290 all‐cause anaphylaxis. The cumulative number on has gradually increased over time, with dramatic increase after 2020, owing COVID‐19 mRNA typhoid most anaphylactic (ROR: 4.35; IC 0.25 : 1.86), followed by encephalitis (3.27; 1.45), hepatitis B (2.69; 1.30), cholera (2.65; 0.54), A (2.44; 1.12), influenza (2.36; 1.16), inactivated whole‐virus (2.21; 1.02), (1.89; 0.79). In terms age‐ sex‐specific risks, develop more frequently females at young ages. Ad5‐vectored vaccine highest fatality rate (15.0%). Conclusions Although multiple various spectra risks anaphylaxis, clinicians should recognize possibility occurring all vaccines, particularly consider reports. Further warranted better ways preventing

Language: Английский

Citations

27