Published: Jan. 1, 2024
Language: Английский
Nature Reviews Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 29, 2025
Language: Английский
Citations
2
Bioactive Materials, Journal Year: 2024, Volume and Issue: 35, P. 447 - 460
Published: Feb. 17, 2024
Atherosclerosis is featured as chronic low-grade inflammation in the arteries, which leads to formation of plaques rich lipids. M2 macrophage-derived extracellular vesicles (M
Language: Английский
Citations
13
Atherosclerosis, Journal Year: 2025, Volume and Issue: unknown, P. 119110 - 119110
Published: Jan. 1, 2025
Language: Английский
Citations
1
Drug Delivery, Journal Year: 2025, Volume and Issue: 32(1)
Published: April 29, 2025
Primary bronchus cancer is one kind of lung with a very high mortality rate. Magnetic drug targeting (MDT) technology could concentrate drugs in specific area, which have useful application therapy. Due to bulk superconducting magnet's ability generate superior magnetic field strength and gradient comparison conventional permanent magnets, there great potential for achieving MDT external the body. However, current research this area still its infancy, numerical simulations exploring guidance been limited only two-dimensional geometries, limits further exploration toward clinical transformation. In work, three-dimensional magnet model built finite-element software package COMSOL Multiphysics. The used simulate delivery process via magnet. influence various parameters on capture efficiency investigated, including lung-magnet distance, superconductor properties, particle physiological or tumor structural parameters. results demonstrate that can effectively improve carriers within suitable distance outside body, potentially guide design practical, system near future.
Language: Английский
Citations
1
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Journal Year: 2025, Volume and Issue: unknown, P. 119911 - 119911
Published: Jan. 1, 2025
Language: Английский
Citations
0
Molecules, Journal Year: 2025, Volume and Issue: 30(4), P. 962 - 962
Published: Feb. 19, 2025
Cardiovascular diseases (CVDs) represent a leading global health crisis, significantly impairing patients' quality of life and posing substantial risks to their survival. Conventional therapies for CVDs often grapple with challenges such as inadequate targeting precision, suboptimal therapeutic efficacy, potential adverse side effects. To address these shortcomings, researchers are intensively developing advanced drug delivery systems characterized by high specificity selectivity, excellent biodegradability, superior biocompatibility, minimal toxicity. These innovative enable the precise pharmaceuticals drug-loading capacities, leakage, expansive specific surface areas, thereby enhancing outcomes. In this review, we summarize classify various materials application values. We also evaluate feasibility efficacy viral non-viral vectors treatment CVDs, existing limitations prospects discussed. hope that review will provide new perspectives future development ultimately contributing improved patient care
Language: Английский
Citations
0
Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216590 - 216590
Published: March 4, 2025
Language: Английский
Citations
0
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 161356 - 161356
Published: March 1, 2025
Language: Английский
Citations
0
Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 24, 2025
Abstract Magnetic ordering modulation is essential for enhancing the functionality of materials and devices. However, achieving precise control over orientation positioning magnets within nanostructures through spatial manipulation remains a significant challenge due to magnetic self‐aggregation. Herein, strategy proposed quantitatively regulate viscous forces acting on particles spray stream under an applied electric field, modifying kinetic energy customize distribution. Notably, this general approach applicable various sizes shapes, including cubes, spheres, ellipses, peanut‐shaped, ranging from tens nanometers several microns. Micromagnetic simulations validate nanoscale spacing units corresponding interactions, providing new insights into relationship between distribution loss. The exchange coupling well‐aligned ferromagnetic cubes in Fe‐3@C@Fe tube results prominent multifold enhancement saturation magnetization intensity, with permeability substantially increasing by two orders magnitude, particularly at high frequencies. Meanwhile, abundant heterogeneous interfaces trigger polarization effects, which synergistically facilitate improved electromagnetic absorption ability. This work opens avenues creating complex superstructures unique functionalities advanced
Language: Английский
Citations
0
Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16
Published: March 13, 2025
Background Calcific aortic valve stenosis (CAVS) is a common cardiovascular condition associated with significant adverse events and high mortality rates. Unfortunately, there are currently no effective pharmacological treatments to halt or prevent its progression. Through our analysis of global trends treatment strategies, we have identified valuable insights promising therapeutic possibilities. Additionally, by utilizing bibliometric visualization techniques, provide comprehensive overview the current research landscape in this field. Method According design idea, used Web Science database select publications on related treatments. VOSviewer CiteSpace analysis, total 787 articles been analyzed September 2024. We also summarize explore most prolific authors, countries, journals institutions that publish articles. Results A visual collected reveals Canada United States highest publication volumes Among institutions, Harvard University U.S. leads count, followed Laval California The top three hotspots stenosis, calcification, journal number area Frontiers Cardiovascular Medicine, Catheterization Interventions Arteriosclerosis, Thrombosis Vascular Biology. Furthermore, CAVS spans various directions focuses, including approaches, pathogenesis, diagnostic methods. Conclusion Research into has advanced significantly over years. While interventional surgical replacement remains mainstay for they insufficient fully meet needs patient. Emerging priorities now focus improving diagnostics, exploring innovative therapies, uncovering disease mechanisms, developing novel drugs. These findings highlight evolving demands field underscore need continued address these challenges.
Language: Английский
Citations
0