Cancers,
Journal Year:
2024,
Volume and Issue:
16(15), P. 2691 - 2691
Published: July 29, 2024
Lung
cancer
is
the
leading
cause
of
death
among
all
oncological
diseases
worldwide.
This
applies
to
both
women
and
men;
however,
incidence
mortality
on
rise.
In
2020,
lung
was
responsible
for
1.8
million
deaths
(18%).
More
than
90%
cases
77.1%
occur
in
countries
with
high
very
HDI
(human
development
index)
values.
The
aim
our
study
present
trends
most
recent
studies
aimed
at
screening.
face
persistently
rate,
conducting
research
extending
already-implemented
diagnostic
algorithms
behavioural
interventions
focused
smoking
cessation
recommended.
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: May 21, 2024
Transdermal
delivery
of
sparingly
soluble
drugs
is
challenging
due
to
their
low
solubility
and
poor
permeability.
Deep
eutectic
solvent
(DES)/or
ionic
liquid
(IL)-mediated
nanocarriers
are
attracting
increasing
attention.
However,
most
them
require
the
addition
auxiliary
materials
(such
as
surfactants
or
organic
solvents)
maintain
stability
formulations,
which
may
cause
skin
irritation
potential
toxicity.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(28)
Published: April 25, 2024
Abstract
Chirality‐driven
self‐sorting
plays
an
essential
role
in
controlling
the
biofunction
of
biosystems,
such
as
chiral
double‐helix
structure
DNA
from
self‐recognition
by
hydrogen
bonding.
However,
achieving
precise
control
over
self‐sorted
structures
and
their
functional
properties
for
bioinspired
supramolecular
systems
still
remains
a
challenge,
not
to
mention
realizing
dynamically
reversible
regulation.
Herein,
we
report
unprecedented
saucer[4]arene‐based
charge
transfer
(CT)
cocrystal
system
with
synergistically
induced
triangular
macrocycle
organic
vapors.
It
displays
efficient
chain
length‐selective
vapochromism
toward
alkyl
ketones
due
modulation
optical
vapor‐induced
diverse
structural
transformations.
Experimental
theoretical
studies
reveal
that
unique
vapochromic
behavior
is
mainly
attributed
formation
homo‐
or
heterochiral
assemblies
different
ketone
guests,
which
differ
dramatically
solid‐state
superstructures
CT
interactions,
thus
influencing
properties.
This
work
highlights
synthetic
systems,
rarely
seen
controllable
at
solid‐vapor
interface
deepens
understanding
sensors.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(54), P. 6889 - 6892
Published: Jan. 1, 2024
The
separation
of
toluene
(Tol)
and
pyridine
(Py)
azeotropes
is
significant
in
the
chemical
industry.
Herein,
we
present
a
new
method
for
energy-efficient
Tol
Py
using
pillar[5]arene-based
adaptive
macrocycle
co-crystals
(MCCs)
that
can
selectively
separate
from
Py/Tol
equimolar
mixture
with
99.2%
purity,
accompanied
by
vapochromic
behavior
white
to
yellow.
Clean Energy Science and Technology,
Journal Year:
2024,
Volume and Issue:
2(2), P. 138 - 138
Published: May 7, 2024
Heteropolyacids
can
retain
water
in
a
proton
exchange
membrane
to
increase
conductivity
at
high
temperatures
and
low
humidity;
however,
their
solubility
leads
leaching,
which
limits
further
application.
Herein,
we
used
phosphotungstic
acid
(HPW)
polydopamine
(PDA)
particles
prepare
water-insoluble
PDA/HPW
hybrid
(PDW)
via
hydrothermal
reaction.
The
amino
groups
of
PDA
PDW
chemically
bonded
HPW
acted
as
an
anchor
for
HPW.
the
sulfonated
poly(ether
ether
ketone)
(SPEEK)
composite
containing
15wt%
(SPEEK/PDW-15)
liquid
was
0.052
S⸱cm–1
25
℃,
63%
higher
than
that
SPEEK
control
(0.032
S⸱cm–1).
SPEEK/PDW-15
also
showed
stable
during
80
days
testing
while
immersed
water.
Frontiers in Immunology,
Journal Year:
2025,
Volume and Issue:
16
Published: Jan. 22, 2025
Cell
penetrating
peptides
(CPPs)
are
usually
positive
charged
and
have
good
cell
membrane
permeability.
Meanwhile,
CPPs
facile
to
synthesize,
can
be
functionalized
satisfy
different
demands,
such
as
cyclization,
incorporating
unnatural
amino
acids,
lipid
conjugation.
These
properties
made
them
efficient
drug-delivery
tools
deliver
therapeutic
molecules
cells
tissues
in
a
nontoxic
manner,
including
small
molecules,
DNA,
siRNA,
proteins
other
various
nanoparticles.
However,
the
poor
serum
stability
low
tumor
targeting
ability
also
hindered
their
broad
application.
Besides,
inappropriate
chemical
modification
lead
disruption
nonspecific
toxicity.
In
this
paper,
we
first
reviewed
recent
advances
CPP
applications
for
cancer
therapy
via
covalent
or
non-covalent
manners.
We
carefully
analyzed
advantages
disadvantages
of
each
modifications
drug
delivery.
Then,
concluded
progress
clinical
trials
diseases.
Finally,
discussed
challenges
opportunities
met
translate
into
applications.
This
review
presented
new
insight
delivery,
which
could
provide
advice
on
design
clinically
effective
systemic
delivery
systems
using
CPPs.
Inorganic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 20, 2025
The
planar
bis-chelated
complex
[Pd(N∩O)2]
(1;
N∩O
=
4-MeC5H3NNC(O)NMe2)
exhibits
two
distinct
stacking
modes
with
electron-deficient
aromatics:
π···π
hexafluorobenzene
(C6F6)
versus
charge-transfer
π–hole
interactions
1,2,4,5-tetracyanobenzene
(TCB).
Cocrystallization
of
the
C6F6
or
TCB
yields
cocrystals
1·3(C6F6)
and
1·2TCB,
respectively,
which
display
different
colors
patterns
despite
similar
structural
motifs.
Comprehensive
analysis
using
X-ray
diffraction,
combined
quantum
theory
atoms-in-molecules
(QTAIM),
an
independent
gradient
model
based
on
Hirshfeld
partition
(IGMH),
extended
transition
state
natural
orbital
for
chemical
valence
charge
displacement
function
(ETS-NOCV/CDF),
many-body
interaction
analysis,
symmetry-adapted
perturbation
(SAPT),
reveals
fundamentally
mechanisms.
In
1·3(C6F6),
is
primarily
governed
by
intermolecular
polarization
without
significant
transfer,
dispersion
forces
contributing
approximately
70%
attractive
energy.
contrast,
1·2TCB
pronounced
transfer
(35
me)
inductive
components
alongside
forces,
characteristic
interactions.
This
dichotomy
in
behavior
provides
new
insights
into
nature
organic–inorganic
assemblies
demonstrates
that
seemingly
can
arise
from
distinctly
combinations
noncovalent
essential
rational
crystal
engineering
hybrid
materials.
