Synthesis of lactones and lactams via C(sp3)–H bond functionalization DOI

E. Premkumar,

Ramdas Sreedharan,

Premananda Ghosh

et al.

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

In this review, we have showcased the diverse aspects of transition-metal catalysis, biocatalysis, and photocatalytic C(sp 3 )–H bond functionalization to access lactones lactams.

Language: Английский

Unified approaches in transition metal catalyzed C(sp3)–H functionalization: recent advances and mechanistic aspects DOI
Jagrit Grover,

Amal Tom Sebastian,

S.K. Maiti

et al.

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Direct alteration of unactivated C–H bonds organic building blocks.

Language: Английский

Citations

1
A Catalytic Version of the Knorr Pyrrole Synthesis Permits Access to Pyrroles and Pyridines DOI

Max Leinert,

Τ. Irrgang, Rhett Kempe

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: 146(46), P. 32098 - 32104

Published: Nov. 11, 2024

Aromatic N-heterocycles, such as pyrroles and pyridines, are important natural products bulk fine chemicals with numerous applications active ingredients of pharmaceuticals agrochemicals, catalysts, in materials sciences. We report here a catalytic version the Knorr pyrrole synthesis which simple diversely available starting materials, 1,2-amino alcohols or 1,3-amino keto esters, undergo dehydrogenative coupling to form respectively. Our reaction forms hydrogen collectible (and usable) byproduct is mediated by well-defined Mn catalyst. The highly functionalized heterocycles was demonstrated, 35 compounds, not yet reported literature, were introduced.

Language: Английский

Citations

4
Adsorption and reaction of 2-methylbenzimidazole molecules on a partially oxidized Cu(110) surface DOI

Minlu Zhou,

Xinle Lu,

Rong Sun

et al.

The Journal of Chemical Physics, Journal Year: 2025, Volume and Issue: 162(17)

Published: May 2, 2025

N-Heterocyclic carbenes (NHCs) have emerged as a promising candidate for functionalizing and modifying metal surfaces. Despite extensive research, the influence of oxides, which frequently occur on surfaces, adsorption behavior NHCs has received limited attention at nanometric scale. In this study, configurations reactions 2-methylbenzimidazole (MBI) molecules CuO/Cu(110) surface were investigated using scanning tunneling microscopy non-contact atomic force (nc-AFM). Following deposition MBI molecules, Cu islands observed, predominantly adsorbed in flat-lying configuration. Comparative experiments conducted bare Cu(110) indicate that dehydrogenation due to cleavage N–H bonds leads CuO reduction release adatoms, subsequently aggregate into islands. Upon annealing 378 K, strips assume tilted configuration, suggesting formation coordination between nitrogen copper atoms. On regions, assemble double-chains, adopting an upright High-resolution nc-AFM images reveal similarity double-chains those step edges, implying atoms are extracted from terraces form slots where preferentially occupy.

Language: Английский

Citations

0
Synthesis of lactones and lactams via C(sp3)–H bond functionalization DOI

E. Premkumar,

Ramdas Sreedharan,

Premananda Ghosh

et al.

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

In this review, we have showcased the diverse aspects of transition-metal catalysis, biocatalysis, and photocatalytic C(sp 3 )–H bond functionalization to access lactones lactams.

Language: Английский

Citations

0