Copper(0)-Catalyzed Reductive Coupling of Disulfurating Reagents and (Hetero)aryl/Alkyl Halides DOI
Wang Chen,

Jiuwen Xu,

Weidong Rao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 18, 2024

Herein, we reported a copper(0)-catalyzed reductive coupling of disulfurating reagents and (hetero)aryl/alkyl halides. Copper(0) can be directly inserted into tetrasulfide then undergoes with (hetero)aryl Iodides to construct disulfide. The method features the unprecedented use (tetrasulfides) in cross-coupling chemistry is convenient broad substrate scopes, even applicable different halogenated hydrocarbons. It worth noting that methodology practical late-stage modification bioactive scaffolds pharmaceuticals. In meantime, synthesis disulfides successfully achieved on gram scale, indicating approach highly valuable.

Language: Английский

Dual Copper/Photoredox Catalysis for Radical-Mediated Arylation and Alkylation of Sulfenamides DOI
Mingjun Zhang,

Yuhao Tan,

Hehe Yang

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 4007 - 4016

Published: Feb. 20, 2025

Language: Английский

Citations

0
Biocompatible C-S bond construction for diarylmethyl thioethers DOI Creative Commons
Zhenwei Zhang, Tao Xu,

C. Ju

et al.

Green Synthesis and Catalysis, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
Benzothiazolines Acting as Carbanion and Radical Transfer Reagents in Carbon–Carbon Bond Construction DOI Creative Commons
Xiaotang Chen,

Bao‐Chen Qian

Molecules, Journal Year: 2025, Volume and Issue: 30(8), P. 1711 - 1711

Published: April 11, 2025

Traditionally employed as hydrogenation reagents, benzothiazolines have emerged versatile carbanion and radical transfer playing a vital role in the construction of various carbon–carbon bonds. The cutting-edge progress photochemistry chemistry prompted study visible light-driven reactions, bringing into vibrant focus. Their chemical processes been uncovered to encompass variety activation mechanisms, with five distinct modes having identified. This work reviews innovative applications donors alkyl or acyl groups, achieving hydroalkylation hydroacylation substitution. By examining their diverse this review highlights potential serving groups for further research development. Moreover, will offer exemplary inspiration synthetic chemists, contributing ongoing evolution utility organic synthesis.

Language: Английский

Citations

0
Electron-donor-acceptor (EDA) complex-driven regioselective vicinal and oxidative geminal functionalization of alkynes† DOI

Dinabandhu Barik,

Nikita Chakraborty, Ashish Kumar Sahoo

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

A visible-light-initiated electron-donor-acceptor (EDA) complex-driven regioselective vicinal and oxidative geminal thiosulfonylation of alkynes is presented. Organic thiosulfonates act as an acceptor, producing either sulfonyl (RSO

Language: Английский

Citations

2
Copper(0)-Catalyzed Reductive Coupling of Disulfurating Reagents and (Hetero)aryl/Alkyl Halides DOI
Wang Chen,

Jiuwen Xu,

Weidong Rao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 18, 2024

Herein, we reported a copper(0)-catalyzed reductive coupling of disulfurating reagents and (hetero)aryl/alkyl halides. Copper(0) can be directly inserted into tetrasulfide then undergoes with (hetero)aryl Iodides to construct disulfide. The method features the unprecedented use (tetrasulfides) in cross-coupling chemistry is convenient broad substrate scopes, even applicable different halogenated hydrocarbons. It worth noting that methodology practical late-stage modification bioactive scaffolds pharmaceuticals. In meantime, synthesis disulfides successfully achieved on gram scale, indicating approach highly valuable.

Language: Английский

Citations

1