Recent advances in controllable/divergent synthesis DOI Creative Commons
Jingyu Cao, Leiyang Bai, Xuefeng Jiang

et al.

Beilstein Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: 21, P. 890 - 914

Published: May 7, 2025

The development of streamlined methodologies for the expeditious assembly structurally diverse organic architectures represents a paramount objective in contemporary synthetic chemistry, with far-reaching implications across pharmaceutical development, advanced materials innovation, and fundamental molecular science research. In recent years, controllable/divergent strategies functional molecules using common starting have garnered significant attention due to their high efficiency. This review categorizes literatures focusing on key regulatory factors product divergent formation, which controlling chemical selectivity primarily relies ligands, metal catalysts, solvents, time, temperature, acids/bases, subtle modifications substrates. To gain deeper understanding mechanisms underlying reaction activity differentiation, provides systematic analysis critical steps through specific case studies. It is hoped that synthesis concept will spark interest practitioners aficionados delve into discipline pursue novel advancements realm synthesis.

Language: Английский

Recent advances in controllable/divergent synthesis DOI Creative Commons
Jingyu Cao, Leiyang Bai, Xuefeng Jiang

et al.

Beilstein Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: 21, P. 890 - 914

Published: May 7, 2025

The development of streamlined methodologies for the expeditious assembly structurally diverse organic architectures represents a paramount objective in contemporary synthetic chemistry, with far-reaching implications across pharmaceutical development, advanced materials innovation, and fundamental molecular science research. In recent years, controllable/divergent strategies functional molecules using common starting have garnered significant attention due to their high efficiency. This review categorizes literatures focusing on key regulatory factors product divergent formation, which controlling chemical selectivity primarily relies ligands, metal catalysts, solvents, time, temperature, acids/bases, subtle modifications substrates. To gain deeper understanding mechanisms underlying reaction activity differentiation, provides systematic analysis critical steps through specific case studies. It is hoped that synthesis concept will spark interest practitioners aficionados delve into discipline pursue novel advancements realm synthesis.

Language: Английский

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