Electromagnetic fields regulate iron metabolism: From mechanisms to applications DOI Creative Commons

Shenghang Wang,

Jiancheng Yang,

Chenxiao Zhen

et al.

Journal of Advanced Research, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Electromagnetic fields (EMFs), as a form of physical therapy, have been widely applied in biomedicine. Iron, the most abundant trace metal living organisms, plays critical role various physiological processes, and imbalances its metabolism are closely associated with development progression numerous diseases. Numerous studies demonstrated that EMF exposureinduces significant changes both systemic cellular iron metabolism. This review aims to summarize evidence potential biophysical mechanisms underlying EMFs regulating metabolism, thereby enhancing understanding their biological expanding applications biomedical fields. In this review, we synthesized research findings proposed hypothesis regulate involve special electromagnetic properties iron-containing proteins iron-enriched tissues, well modulation membrane structure function, ion channels, generation activity Reactive Oxygen Species (ROS). Then, summarizes latest advances effects on safety, impact immunoregulation, cardiovascular diseases, neurological orthopedic diabetes, liver injury, cancer.

Language: Английский

Electromagnetic fields regulate iron metabolism: From mechanisms to applications DOI Creative Commons

Shenghang Wang,

Jiancheng Yang,

Chenxiao Zhen

et al.

Journal of Advanced Research, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Electromagnetic fields (EMFs), as a form of physical therapy, have been widely applied in biomedicine. Iron, the most abundant trace metal living organisms, plays critical role various physiological processes, and imbalances its metabolism are closely associated with development progression numerous diseases. Numerous studies demonstrated that EMF exposureinduces significant changes both systemic cellular iron metabolism. This review aims to summarize evidence potential biophysical mechanisms underlying EMFs regulating metabolism, thereby enhancing understanding their biological expanding applications biomedical fields. In this review, we synthesized research findings proposed hypothesis regulate involve special electromagnetic properties iron-containing proteins iron-enriched tissues, well modulation membrane structure function, ion channels, generation activity Reactive Oxygen Species (ROS). Then, summarizes latest advances effects on safety, impact immunoregulation, cardiovascular diseases, neurological orthopedic diabetes, liver injury, cancer.

Language: Английский

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