Centrifugal Spinning-Derived Biomimetic Aerogel for Rapid Hemostasis with Minimal Blood Loss DOI

Fen Fu,

Xiaoyu Zuo, Yuhan Wang

et al.

Nano Letters, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

For emergency treatment, especially in situations where rapid and effective hemostasis is required beyond the natural clotting mechanisms, advanced materials designed to reduce bleeding time minimize blood loss have become an urgent need. Herein, a root hair-inspired aerogel developed, which characterized by 99.99% interconnected pore structure three-dimensional network constructed blocked aqueous isocyanates cross-linked grooved cellulose acetate wrinkled thermoplastic polyurethane fibers via centrifugal spinning. The exhibits enhanced water absorption minimal adsorption through coagulation cascade activation. In vivo studies using rat tail, hepatic, renal injury models demonstrate substantial reduction (∼94%) (∼78%) compared commercial hemostats. developed offers promising solution for hemorrhage control.

Language: Английский

Enhanced Anti‐Migration of Organic Antioxidants via Chitosan‐Encapsulated Ultrathin Intercalated Layered Double Hydroxides Fabricated by a Nucleation‐Encapsulation Coupling Strategy DOI
Zijia Li,

Menghua Zhao,

Guan Jun

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

Abstract Antioxidants play a crucial role in inhibiting polypropylene (PP) oxidative damage and extending polymer lifetime. However, the high migration rate limited efficiency reduced protection, often requiring overdosing, which raises environmental health issues. Herein, more sustainable solution involves an ultrathin antioxidant intercalated layered double hydroxides (LDHs) with chitosan (CS) encapsulation to block antioxidants by tuning CS molecular weight fully encapsulate LDH unit. The optimized inhibits without hindering interlayer diffusion of radicals, thereby providing better protection for PP. 200kCS‐3L‐LDH/PP low phenolic (3,5‐Di‐tert‐butyl‐4‐hydroxyphenylpropionic acid, abbreviated as DBHP) encapsulated MW = 200k at level 11.6% (actual percentage weight), demonstrates ratio 8.17% after 204 h ethanol 60 °C overlong thermal aging resistance time (1920 min) under air, surpassing conventional most resistant product currently on market 1010/PP (46.0% 640 min, respectively). Such “Russian doll” structure offers promising way enhance PP excellent anti‐migration antioxidative performance, while valuable strategy design controlled release if desired species LDHs.

Language: Английский

Citations

0
Carboxymethyl chitosan modified double-skeleton hydrogel electrolyte enables high performance for flexible zinc-air batteries DOI
Zhe Liu, Lei Chen, Xiaoliang Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 303, P. 140678 - 140678

Published: Feb. 4, 2025

Language: Английский

Citations

0
Crosslinking network design of cellulose-based conductive gels: Mechanism, strategies, and characterization DOI

Haocheng Fu,

Bin Wang, Jinpeng Li

et al.

Progress in Materials Science, Journal Year: 2025, Volume and Issue: unknown, P. 101476 - 101476

Published: March 1, 2025

Language: Английский

Citations

0
Centrifugal Spinning-Derived Biomimetic Aerogel for Rapid Hemostasis with Minimal Blood Loss DOI

Fen Fu,

Xiaoyu Zuo, Yuhan Wang

et al.

Nano Letters, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

For emergency treatment, especially in situations where rapid and effective hemostasis is required beyond the natural clotting mechanisms, advanced materials designed to reduce bleeding time minimize blood loss have become an urgent need. Herein, a root hair-inspired aerogel developed, which characterized by 99.99% interconnected pore structure three-dimensional network constructed blocked aqueous isocyanates cross-linked grooved cellulose acetate wrinkled thermoplastic polyurethane fibers via centrifugal spinning. The exhibits enhanced water absorption minimal adsorption through coagulation cascade activation. In vivo studies using rat tail, hepatic, renal injury models demonstrate substantial reduction (∼94%) (∼78%) compared commercial hemostats. developed offers promising solution for hemorrhage control.

Language: Английский

Citations

0