Research Progress on the Exacerbation of Lipid Metabolism by Malassezia and Its Impact on the Skin Barrier Function DOI Creative Commons
Yating Cheng, Jianhang Cong,

Jiahui Xu

et al.

Cosmetics, Journal Year: 2025, Volume and Issue: 12(2), P. 67 - 67

Published: April 3, 2025

The study of the fungal communities skin constitutes a pivotal component microbiome research. Within these communities, genus Malassezia stands out as major constituent, representing 50% to 80% total colonization on healthy individuals. excessive growth or metabolic irregularities this are intimately connected with onset various disorders that intrinsically linked its lipid-dependent nature. Cutaneous lipid metabolism is indispensable for maintaining barrier function and health. possesses ability encode multiple lipase genes, secretion lipases plays role in survival strategies fungi. This review explores recent advances ecological niche microecological homeostasis, mechanism disrupting lipids through catabolic metabolites, relationship between disruption diseases. offers reference future research mechanisms by which affects provides theoretical foundation development innovative therapeutic approaches dermatological conditions.

Language: Английский

Research Progress on the Exacerbation of Lipid Metabolism by Malassezia and Its Impact on the Skin Barrier Function DOI Creative Commons
Yating Cheng, Jianhang Cong,

Jiahui Xu

et al.

Cosmetics, Journal Year: 2025, Volume and Issue: 12(2), P. 67 - 67

Published: April 3, 2025

The study of the fungal communities skin constitutes a pivotal component microbiome research. Within these communities, genus Malassezia stands out as major constituent, representing 50% to 80% total colonization on healthy individuals. excessive growth or metabolic irregularities this are intimately connected with onset various disorders that intrinsically linked its lipid-dependent nature. Cutaneous lipid metabolism is indispensable for maintaining barrier function and health. possesses ability encode multiple lipase genes, secretion lipases plays role in survival strategies fungi. This review explores recent advances ecological niche microecological homeostasis, mechanism disrupting lipids through catabolic metabolites, relationship between disruption diseases. offers reference future research mechanisms by which affects provides theoretical foundation development innovative therapeutic approaches dermatological conditions.

Language: Английский

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