Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: March 30, 2025

Epoxides are significant chemicals that utilized across various fields. Here, we describe an unprecedented photochemical rearrangement approach for synthesizing a diverse collection of epoxides enabled by energy transfer catalysis under visible light conditions. The process enables the easy preparation α-amino-substituted epoxide derivatives with broad substrate scope, functional group tolerance, and mild reaction Furthermore, this photorearrangement has also been applied in complex architectures, could be easily transferred to amino alcohol derivatives. Overall, oxa-π, σ-methane provides complementary strategy existing methods through catalysis.

Language: Английский