Investigating the Alleviating Effect of Fucoidan from Apostichopus japonicus on Ulcerative Colitis by Mice Experiments and In Vitro Simulation of Human Fecal Fermentation
Lingyan Xue,
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Yuchen Huan,
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Yaoguang Chang
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et al.
Foods,
Journal Year:
2025,
Volume and Issue:
14(4), P. 574 - 574
Published: Feb. 9, 2025
Fucoidan
from
Apostichopus
japonicus
(Aj-FUC)
is
a
marine
polysaccharide
extracted
the
high-quality
sea
cucumber,
which
has
received
increasing
attention
for
its
multiple
biological
activities.
In
this
study,
Aj-FUC
was
extracted,
and
basic
structure
characterized,
while
alleviating
efficacy
of
on
ulcerative
colitis
(UC)
investigated
using
C57BL/6
mice.
The
improvement
fecal
gut
microbiota
in
healthy
individuals
inflammatory
bowel
disease
(IBD)
patients
explored
vitro
simulated
fermentation.
results
reflected
that
treatment
attenuated
histopathological
damage
associated
with
colitis,
reduced
levels
IL-6,
IL-1β,
TNF-α.
also
upregulated
expression
ZO-1
occludin,
thereby
aiding
repair
intestinal
barrier.
Furthermore,
enhanced
short-chain
fatty
acids
(SCFAs)
helped
restore
balance
microbiota,
particularly
by
relative
abundance
Akkermansia.
simulation
fermentation
showed
could
modulate
IBD
increase
beneficial
bacteria.
conclusion,
study
highlights
can
alleviate
UC
modulating
factors,
improving
barrier,
regulating
flora
variety
ways.
Language: Английский
sRecirculating aquaculture-fasting strategy (RAS F) to modulate gut microbiota and enhance the fish meat quality of bighead carp (Aristichthys nobilis)
Weifa Su,
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Xini Wang,
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Weichao Bu
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et al.
Food Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 143946 - 143946
Published: March 1, 2025
Language: Английский
The association between the health of the intestines and the human body with Akkermansia muciniphila
Seyed Ali Sadr Tabatabaei,
No information about this author
Hedie Yousefi Ghadim,
No information about this author
Sara Alaei
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et al.
The Microbe,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100352 - 100352
Published: April 1, 2025
Language: Английский
Rehmannia glutinosa polysaccharides alleviate cyclophosphamide-induced immunosuppression by enhancing immunity and restoring intestinal homeostasis
Lin Yu,
No information about this author
Xiaofeng Shi,
No information about this author
Xuanqi Lu
No information about this author
et al.
International Journal of Biological Macromolecules,
Journal Year:
2025,
Volume and Issue:
311, P. 143692 - 143692
Published: April 30, 2025
Language: Английский
What exactly happens to rats that drink different types of sweetness water over a long time:A comparison with sucrose, artificial sweeteners and natural sweeteners
Chuansong Zhan,
No information about this author
Lu Dai,
No information about this author
Ruiyi Zhang
No information about this author
et al.
Journal of Functional Foods,
Journal Year:
2025,
Volume and Issue:
127, P. 106715 - 106715
Published: March 16, 2025
Language: Английский