Leveraging OGTT derived metabolic features to detect Binge-eating disorder in individuals with high weight: a “seek out” machine learning approach

Translational Psychiatry, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 18, 2025

Binge eating disorder (BED) carries a 6 times higher risk for obesity and accounts roughly 30% of type 2 diabetes cases. Timely identification early glycemic disturbances comprehensive treatment can impact on the likelihood associated metabolic complications overall outcome. In this study, machine learning techniques were applied to static dynamic glucose-derived measures detect BED among 281 individuals with high weight. Data from classic (2 h) extended (5 glucose load computed by multiple algorithms two models most relevant features trained within sample. The then tested an independent cohort (N = 21). model based 5 h-long exhibited best performance (sensitivity 0.75, specificity 0.67, F score 0.71) diagnosing in 7 out 10 Sex, HOMA-IR, HbA1c plasma different times, hypoglycemia events sensitive diagnosis. This study is first use hallmarks train ML detecting at complications. objective reliable might prompt complications, enabling timely tailored multidisciplinary treatment.

Language: Английский

---

Frequency and Associations of Binge-Eating Behavior Patterns With Gastrointestinal Symptoms: A Cross-Sectional Study

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 22, 2025

Background and aim Binge-eating behavior (BED) poses a significant public health issue worldwide, as it has severe implications for both the physical gastrointestinal symptoms. The present study evaluated prevalence of BED with these Furthermore, we assessed correlation between binge eating Methods Two hundred nineteen patients were enrolled in from OPD Department Gastroenterology, Mayo Hospital Lahore. After informed consent, patient's demographics complete medical history obtained. Then, asked about their symptoms heartburn, diarrhea, weight gain, bloating, pain abdomen using questionnaire. Frequency percentages will be calculated categorical variables, chi-square used to assess associations. Results Out 219, 114 (52.1%) male, 105 (47.9%) female. minimum age participants was 15, maximum 56, mean 31.10 ± 8.214. Eighty-three (27.9%) had one episode while having binge-eating behavioral pattern, 93 (42.5%) two three episodes, 43 (19.6%) more than episodes last six months. And hospital visits, 128 (58.4%) heartburn. Eighty (36.9%) suffered 86 (39.3%) constipation/bloating, 118 (53.9%) abdomen, diarrhea. There association heartburn p-value 0.009 (≤0.05), diarrhea that 0.008 (≤0.05). Conclusion This emphasizes strong habits problems, including These results highlight necessity all-encompassing management approaches take into account BED's psychological components.

Language: Английский

---

Binge Eating Disorder and Metabolic Syndrome: Shared Mechanisms and Clinical Implications

Healthcare, Journal Year: 2025, Volume and Issue: 13(5), P. 482 - 482

Published: Feb. 23, 2025

Background: Binge eating disorder (BED) is characterized by episodes of uncontrollable eating, defined the rapid consumption large quantities food over a short period. This condition associated with variety psychological and non-psychological factors, including behavioral, biological, genetic, neurological, pharmacological influences, all which adversely affect patients' daily lives. BED linked to numerous health consequences, such as obesity, atherosclerosis, diabetes, chronic pain, hypertension. Although not exclusive individuals it more prevalent in this population, who also face heightened risk developing metabolic syndrome (MetS). The latter cluster five factors-obesity, hyperlipidemia, hyperinsulinemia, hypertension, hyperglycemia-that significantly increase likelihood diseases. Methods: narrative review synthesizes existing research explore association between MetS, examining shared pathophysiological mechanisms clinical implications. It highlights role escalating insecurity ongoing political, economic, crises development BED. Results: MetS components, type 2 dyslipidemia, contributing increased morbidity mortality. Beyond body weight, neurological factors mediate relationship. Conclusions: strongly through biological pathways. Early detection, integrated management strategies, further are crucial addressing public challenges posed association.

Language: Английский

---

Somatic Comorbidities in People with Eating Disorders

Published: Jan. 1, 2025

Language: Английский

---

Affective Trajectories of Binge Eating, Purging, and Exercise Among Sexual Minority Men

International Journal of Eating Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

In the context of eating disorders, negative reinforcement model states that binge and purging reduce affect. Expanding on prior work mostly conducted with women, this study examines affective trajectories surrounding eating, purging, exercise among sexual minority men. We a 7-day experience sampling community sample 529 Participants received eight daily surveys assessing positive affect, exercise. assessed pre- post-behavior using multilevel polynomial regression models. Across 7 days, 37% participants binged, 10% purged, 70% exercised at least once. Before affect increased decreased, indicating worsening mood. After improved Positive post-binge but did not change post-purge. Results were consistent binge-only purge-only days (i.e., no co-occurrences or same day). Exercise followed different pattern: before exercise, change, increased. However, increase after exercise-only occasions. These findings support Surprisingly, was consistently associated changes in dampened suggest clinicians should incorporate regulation training treating to men navigate stressors.

Language: Английский

---