Origins of symbiosis: shared mechanisms underlying microbial pathogenesis, commensalism and mutualism of plants and animals

FEMS Microbiology Reviews, Journal Year: 2022, Volume and Issue: 47(6)

Published: Dec. 12, 2022

Abstract Regardless of the outcome symbiosis, whether it is pathogenic, mutualistic or commensal, bacteria must first colonize their hosts. Intriguingly, closely related that diverse hosts with outcomes symbiosis have conserved host-association and virulence factors. This review describes commonalities in process becoming host associated amongst lifestyles. Whether a pathogen, commensal mutualist, sense presence migrate towards host, compete for space nutrients other microbes, evade immune system, change physiology to enable long-term association. We primarily focus on well-studied taxa, such as Pseudomonas, associate model plant animal hosts, far-ranging symbiotic outcomes. Given importance opportunistic pathogens chronic infections both human health agriculture, understanding mechanisms facilitate relationships between will help inform development disease treatments humans, plants we eat.

Language: Английский

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Gene modelling and annotation for the Hawaiian bobtail squid, Euprymna scolopes

Scientific Data, Journal Year: 2024, Volume and Issue: 11(1)

Published: Jan. 6, 2024

Abstract Coleoid cephalopods possess numerous complex, species-specific morphological and behavioural adaptations, e.g., a uniquely structured nervous system that is the largest among invertebrates. The Hawaiian bobtail squid ( Euprymna scolopes ) one of most established cephalopod species. With its recent publication chromosomal-scale genome assembly regulatory genomic data, it also emerges as key model for gene regulation evolution. However, latest has been lacking native set. Our manuscript describes generation new long-read transcriptomic data and, made using this combined with plethora publicly available protein sequence reference annotation E. .

Language: Английский

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Evolutionary history influences the microbiomes of a female symbiotic reproductive organ in cephalopods

Applied and Environmental Microbiology, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 5, 2024

ABSTRACT Many female squids and cuttlefishes have a symbiotic reproductive organ called the accessory nidamental gland (ANG) that hosts bacterial consortium involved with egg defense against pathogens fouling organisms. While ANG is found in multiple cephalopod families, little known about global microbial diversity of these symbionts. We used 16S rRNA gene community analysis to characterize microbiome from different species assess relationship between host symbiont phylogenies. The 11 cephalopods four families (superorder: Decapodiformes) span seven geographic locations was characterized. Bacteria class Alphaproteobacteria, Gammaproteobacteria , Flavobacteriia were all species, yet amplicon sequence variants by distance metrics revealed significant difference microbiomes (weighted/unweighted UniFrac, Bray–Curtis, P = 0.001). Despite being collected widely disparate locations, members family Sepiolidae (bobtail squid) shared many taxa including (~50%) Opitutae (Verrucomicrobia) Ruegeria (Alphaproteobacteria) species. Furthermore, we tested for phylosymbiosis positive correlation phylogenetic dissimilarity (Mantel test r 0.7). These data suggest closely related sepiolids select distinct symbionts similar taxa. Overall, ANGs harbor thus offer diverse explore antimicrobial activity other functional roles fitness. IMPORTANCE aquatic organisms recruit environment provide variety functions, pathogens. Some (squids, bobtail squids, cuttlefish) contains protects eggs wide distribution cephalopods, whether they share unknown. Here, studied distributed over broad range representing 15–120 million years divergence. some taxa, but each had unique members. Additionally, host–symbiont phylogenies suggests evolutionary histories partners been important shaping microbiome. This study advances our knowledge cephalopod–bacteria relationships provides foundation defensive systems.

Language: Английский

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A conserved genetic basis for commensal-host specificity through live imaging of colonization dynamics

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: April 19, 2024

Abstract Animals throughout the metazoa selectively acquire specific symbiotic gut bacteria from their environment that aid host fitness. Current models of colonization suggest these use weakly receptors to stick tissues and results when they in a region overlaps with nutritional niche. An alternative model is unique receptor-ligand binding interactions provide specificity for target niches. Here we live imaging individual bacterial cells colonizing living Drosophila melanogaster show Lactiplantibacillus plantarum specifically recognizes distinct physical niche gut. We find recognition controlled by island widely conserved commensals pathogens Lactobacillales Clostridia. Our findings indicate genetic mechanism broadly conserved. One-Sentence Summary Host-symbiont encoded provides molecular precision access.

Language: Английский

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Commentary: The microbial dependence continuum: Towards a comparative physiology approach to understand host reliance on microbes

Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, Journal Year: 2024, Volume and Issue: 296, P. 111690 - 111690

Published: July 2, 2024

Language: Английский

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