One Health: a holistic approach for food safety in livestock

Science in One Health, Journal Year: 2022, Volume and Issue: 1, P. 100015 - 100015

Published: Nov. 1, 2022

The food safety of livestock is a critical issue between animals and humans due to their complex interactions. Pathogens have the potential spread at every stage animal handling process, including breeding, processing, packaging, storage, transportation, marketing consumption. In addition, application antibiotic usage in domestic controversial because, while they can combat food-borne zoonotic pathogens promote growth productivity, also lead transmission antibiotic-resistant microorganisms genes across species habitats. Coevolution microbiomes may occur as well which alter structure human microbiome through One Health holistic approach systematically understand relationships among humans, environments provide effective countermeasures solve problems aforementioned. This paper depicts main pathogen spectrum products, summarizes flow bacteria along food-chain production, correlation reviewed advocate for deeper interdisciplinary communication collaboration researchers medicine, epidemiology, veterinary medicine ecology approaches address global challenges.

Language: Английский

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Metagenomics of gut microbiome for migratory seagulls in Kunming city revealed the potential public risk to human health

BMC Genomics, Journal Year: 2023, Volume and Issue: 24(1)

Published: May 19, 2023

Seagull as a migratory wild bird has become most popular species in southwest China since 1980s. Previously, we analyzed the gut microbiota and intestinal pathogenic bacteria configuration for this by using 16S rRNA sequencing culture methods. To continue in-depth research on microbiome of seagulls, metagenomics, DNA virome RNA were both investigated their microbial communities abundance diversity study.The metagenomics results showed 99.72% total was bacteria, followed viruses, fungi, archaea eukaryota. In particular, Shigella sonnei, Escherichia albertii, Klebsiella pneumonia, Salmonella enterica flexneri top distributed taxa at level. PCoA, NMDS, statistics indicated some drug resistant genes, such adeL, evgS, tetA, PmrF, evgA accumulated time went from November to January next year, these genes antibiotic efflux. composition demonstrated that Caudovirales virus, Cirlivirales, Geplafuvirales, Petitvirales Piccovirales. Most phages corresponded Enterobacteriaceae Campylobacteriaceae bacterial hosts respectively. Caliciviridae, Coronaviridae Picornaviridae family level animal. Phylogenetic analysis sequences contigs Gammacoronavirus Deltacoronavirus had highly similarity with coronavirus references.In general, characteristics seagulls closely related human activities, multiomics still revealed potential public risk health.

Language: Английский

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Viruses of Freshwater Mussels during Mass Mortality Events in Oregon and Washington, USA

Viruses, Journal Year: 2023, Volume and Issue: 15(8), P. 1719 - 1719

Published: Aug. 11, 2023

Freshwater mussels (Unionida) are globally imperiled, in part due to largely unexplained mass mortality events (MMEs). While recent studies have begun investigate the possibility that mussel MMEs Eastern USA may be caused by infectious diseases, Western received relatively little attention this regard. We conducted a two-year epidemiologic investigation of role viruses ongoing pearlshell (Margaritifera falcata) and ridged (Gonidea angulata) Chehalis River Columbia watersheds USA. characterized viromes hemolymph from 5 locations 2018 2020 using metagenomic methods identified 557 based on assembled contiguous sequences, most which novel. also distribution diversity previously Gammarhabdovirus related pathogenic finfish viruses. Overall, we found few consistent associations between health status. Variation was strongly driven location, with influence date, species, or status, though these variables together only explained ~1/3 variation virome composition. Our results demonstrate freshwater host remarkably diverse viromes, but no single virus combination appears associated morbidity during MMEs. findings implications for conservation imperiled mussels, including efforts enhance natural populations through captive propagation.

Language: Английский

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Gut meta-virome reveals potential zoonotic pathogens and environmental RNA viruses carried by non-human primates

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 8, 2025

Abstract The majority of human infectious diseases originate from mammals and are inherently zoonotic. Non-human primates (NHPs) not only carriers many zoonotic pathogens, but also the best intermediary for virus shift harmless to harmful due their similar phylogenetic relationship with humans. Knowledge NHP viral composition its underlying information can therefore provide an assessment risk cross-species transmission spillover diseases. However, studies that have successfully eliminated effects different natural habitat environments on carriage been limited, making it difficult identify which viruses potentially species-barrier-crossing carried by widely distributed hosts. Here, we analyze excreted in feces hosts reveal presence possible pathogens. Most found come plants eaten them. Analysis evolutionary relationships potential pathogens suggests other clinical isolates genetically correlated HIV, PBV, EV identified. This study provides foundational data surveillance enteroviruses could help be challenging track absence surveillance. Importance As a result internationalization factors, broken through limits geographical units spread into society, causing emerging re-emerging disease hazards. spreads is no means humans overnight. There phenomenon host shift, does necessarily cause intermediate host, causes significant damage when transmitted We focus captive non-human primates, close relatives cities, because shifts related both biological similarity proximity host. Primates may carry currently incapable infecting evolved pathogenic potential. In summary, comprehensive screening nonhuman necessary.

Language: Английский

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Prevalence of Multiple RNA Virus Infections in Nine Types of Commonly Used Laboratory Animals in China

Zoonoses and Public Health, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

ABSTRACT Introduction Laboratory animals are widely used in biomedical research. Surveillance of naturally occurring virus laboratory is important to fully understand the results animal experiment, control laboratory‐acquired infections among research personnel and manage viral transmission within populations. This study aimed investigate prevalence multiple RNA viruses commonly China. Methods We screened for five different potentially zoonotic (astrovirus, coronavirus, hepevirus, hepatovirus picornavirus) that can be transmitted via faecal‐oral route 759 faecal samples collected from nine (mice, rats, monkeys, rabbits, pigs, dogs, ferrets, goats tree shrews) Viral was by broad‐spectrum reverse transcription polymerase chain reaction (RT‐PCR) using primers annealing genome‐conserved regions. The mice rats this were specific‐pathogen‐free. other conventional animals. Results At least one selected detected each sampled types, except shrews. total positive rates astroviruses, coronaviruses, hepeviruses picornaviruses 4.3%, 7.6%, 8.0% 1.1%, respectively. Among these, positivity hepevirus ferrets (41.3%) rabbits (17.8%), astrovirus pigs (75.0%) coronavirus (45.7%) relatively high. negative all Co‐infection with has also been observed rabbits. Conclusions Our findings highlight need surveillance natural

Language: Английский

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