Nanopore Sequencing Enables Comprehensive Transposable Element Epigenomic Profiling

Molecular Cell, Journal Year: 2020, Volume and Issue: 80(5), P. 915 - 928.e5

Published: Nov. 12, 2020

Language: Английский

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Active turnover of DNA methylation during cell fate decisions

Nature Reviews Genetics, Journal Year: 2020, Volume and Issue: 22(1), P. 59 - 66

Published: Oct. 6, 2020

Language: Английский

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Differences between germline genomes of monozygotic twins

Nature Genetics, Journal Year: 2021, Volume and Issue: 53(1), P. 27 - 34

Published: Jan. 1, 2021

Language: Английский

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LncRNA-mediated DNA methylation: an emerging mechanism in cancer and beyond

Journal of Experimental & Clinical Cancer Research, Journal Year: 2022, Volume and Issue: 41(1)

Published: March 15, 2022

DNA methylation is one of the most important epigenetic mechanisms to regulate gene expression, which highly dynamic during development and specifically maintained in somatic cells. Aberrant patterns are strongly associated with human diseases including cancer. How cell-specific established or disturbed a pivotal question developmental biology cancer epigenetics. Currently, compelling evidence has emerged that long non-coding RNA (lncRNA) mediates both physiological pathological conditions. In this review, we provide an overview current understanding lncRNA-mediated methylation, emphasis on roles mechanism cancer, best our knowledge, not been systematically summarized. addition, also discuss potential clinical applications RNA-targeting drug development.

Language: Английский

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Cannabis and synaptic reprogramming of the developing brain

Nature reviews. Neuroscience, Journal Year: 2021, Volume and Issue: 22(7), P. 423 - 438

Published: May 21, 2021

Language: Английский

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