Auricular atrophy

BMJ, Journal Year: 2025, Volume and Issue: unknown, P. e081185 - e081185

Published: Jan. 9, 2025

Language: Английский

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Can physical trauma trigger relapsing polychondritis? The first report from a Chinese cohort and comparison with rheumatoid arthritis and psoriatic arthritis

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

Objectives The triggers of relapsing polychondritis (RPC) are not fully characterized. This study was performed to explore the association between physical trauma and RPC. Methods history 208 patients with RPC from a Chinese cohort reviewed compared that 1134 rheumatoid arthritis (RA) 369 psoriatic (PsA). characteristics survival were analyzed. Results Eighty (38.5%) ever had trauma. number is considerably higher than RA (21.6%, p < 0.0001) PsA (20.6%, 0.0001). A total 48 (23.1%) 52 osteochondral injuries, whereas only 58 (5.1%, 21 (5.7%, injuries. We found more experienced any type trauma, as well in preceding one year , also half year, before disease onset PsA. Traumatic events (osteochondral nonosteochondral) increased onset, especially six months. Patients occurred at time rate airway involvement lower rates those without Conclusion Our findings suggest may be RPC, seem have severe without.

Language: Английский

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Hiding in Plain Sight—Relapsing Polychondritis Disguised as Hip Arthritis: A Case Report and Literature Review

Immunity Inflammation and Disease, Journal Year: 2025, Volume and Issue: 13(2)

Published: Feb. 1, 2025

ABSTRACT Background Relapsing polychondritis (RP) is a rare autoimmune disorder characterized by episodic inflammation of cartilaginous tissues. Its diverse clinical manifestations frequently pose diagnostic challenges and lead to misdiagnosis. Methods We present 59‐year‐old female initially diagnosed with refractory hip osteoarthritis based on persistent left pain unresponsive conventional anti‐inflammatory therapy. Subsequent development stridor dyspnea prompted comprehensive evaluation, including laryngotracheal imaging, serology, multidisciplinary consultation. Diagnostic criteria for RP were applied in accordance revised Michet criteria. Results Tracheal stenosis secondary tracheal chondritis iritis identified, confirming the diagnosis RP. Following initiation corticosteroid therapy, patient exhibited marked improvement. Conclusion This case underscores importance enhanced awareness regarding atypical presentations RP, particularly when accompanied evolving systemic symptoms. A approach advocated facilitate early detection improve outcomes.

Language: Английский

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Differentiation of Relapsing Polychondritis and Auricular Perichondritis by Magnetic Resonance Imaging: A Case Report and Literature Review

Advances in Clinical Medicine, Journal Year: 2025, Volume and Issue: 15(04), P. 1211 - 1216

Published: Jan. 1, 2025

Language: Английский

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Laryngeal involvement in relapsing polychondritis: clinical and CT findings in 173 patients

RMD Open, Journal Year: 2025, Volume and Issue: 11(2), P. e005397 - e005397

Published: April 1, 2025

Introduction/objectives Relapsing polychondritis (RP) is a rare autoimmune disorder primarily affecting cartilaginous structures. We aimed to characterise the clinical features and CT findings of laryngeal involvement in RP, hypothesising that specific patterns correlate with manifestations. Methods retrospectively analysed 173 patients confirmed RP. Demographic data were collected, laryngeal, tracheal, bronchial reviewed. Statistical analyses identified factors associated airway stenosis. Results Notably, 66% asymptomatic displayed evidence damage, 41.1% (44/107), tracheal 80.9% (140/173), 36.4% (63/107). Cricoid erosion broadening mucosal hyperplasia predominant findings. Significant associations included younger age at disease onset (p<0.05), longer duration (p<0.01) multiorgan manifestations (p<0.01). Conclusions Laryngeal common RP manifestations, second only involvement. cricoid are characteristic. Vigilant monitoring recommended for risk facilitate early detection management. Future research should focus on developing targeted interventions this high-risk subgroup patients.

Language: Английский

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Auricular swelling and tenderness with multiple pulmonary nodules

BMJ, Journal Year: 2025, Volume and Issue: 389, P. e082908 - e082908

Published: May 15, 2025

Language: Английский

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Treatment of auricular chondritis with tofacitinib

Indian Journal of Dermatology Venereology and Leprology, Journal Year: 2025, Volume and Issue: 0, P. 1 - 3

Published: May 14, 2025

Language: Английский

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Anakinra in relapsing polychondritis: a case report and review of the literature

Immunotherapy, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 5

Published: Dec. 20, 2024

Relapsing polychondritis is rare and affects non-synovial fibrocartilage. Currently, there a paucity of treatment algorithms, especially for those with refractory disease. A middle-aged man presented affecting the nose, ears, joints, larynx. Two months prior, diagnosis non-arteritic ischemic optic neuropathy was made. Oral prednisolone initiated, over following three years, he had several flares which other treatments were given: moderate dose methotrexate (elevated liver enzymes), azathioprine (gastrointestinal intolerance), mycophenolate (ineffective), tocilizumab (widespread eruption), tofacitinib (acute diverticulitis). Further investigations unremarkable malignancy vasculitis. UBA1 mutation screening negative. Given limited therapeutic options, at lower re-added, but developed acute flare laryngeal symptoms. Anakinra prompting successful wean weeks disease remission. literature review identified 11 publications comprising 25 patients. Of 21 patients anakinra response documented, six (28.6%) symptomatic improvement. In one these patients, co-administration methotrexate. summary, may remain as an option, only subsets in whom many more efficacious have been tried to provide sustained control.

Language: Английский

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A difficult case of relapsing polychondritis that led to persistent obstructive ventilatory defect caused by tracheobronchomalacia

Tenri Medical Bulletin, Journal Year: 2024, Volume and Issue: 27(1), P. 25 - 32

Published: June 30, 2024

Language: Английский

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Recurrent refractory polychondritis: A case report

Ulusal Romatoloji Dergisi, Journal Year: 2024, Volume and Issue: unknown, P. 82 - 86

Published: July 23, 2024

ÖzTekrarlayan polikondrit (TP), kıkırdak ve proteoglikandan zengin dokuların tekrarlayan enflamasyon atakları ile karakterize

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