Initial survey of UK rheumatologists to inform a national cardio-rheumatology strategy DOI

Amr Mohammed,

Rudresh Shukla,

Simon E. Fisher

et al.

Lara D. Veeken, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 15, 2024

Journal Article Accepted manuscript Initial survey of UK rheumatologists to inform a national cardio-rheumatology strategy Get access Amr Mohammed, Mohammed Division Cardiovascular Sciences, Faculty Biology, Medicine & Health, University Manchester, Search for other works by this author on: Oxford Academic PubMed Google Scholar Rudresh Shukla, Shukla Centre Musculoskeletal Research, Simon Fisher, Fisher NIHR-BHF Partnership, Oxford, Maya H Buch UKNIHR Manchester Biomedical Research Centre, NHS Foundation Trust, Corresponding and address: Professor Buch, Dermatological Sciences/School Biological AV Hill Building, Road, UK, M13 9PT, Email: [email protected] Telephone: +44 (0)161 306 0696 Rheumatology, keae567, https://doi.org/10.1093/rheumatology/keae567 Published: 16 October 2024 history Received: 17 July Revision received: 30 September Accepted: 07

Language: Английский

Exploring the Benefits and Prescribing Informations of Combining East Asian Herbal Medicine with Conventional Medicine in the Treatment of Rheumatoid Arthritis: A Systematic Review and Multifaceted Analysis of 415 Randomized Controlled Trials DOI Creative Commons
Hee-Geun Jo, Jihye Seo, Eunhye Baek

et al.

Pharmacological Research, Journal Year: 2025, Volume and Issue: unknown, P. 107616 - 107616

Published: Jan. 1, 2025

Notwithstanding progress in conventional medicine (CM), the management of rheumatoid arthritis (RA) continues to be problematic due factors such as limited patient response treatment and restricted medication access. This study aimed evaluate extent which East Asian herbal with CM combination therapy (EACM) provides additional benefits effectiveness safety. We conducted a comprehensive search across 11 databases English, Chinese, Korean, Japanese for randomized controlled trials. The review followed Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines, using American College Rheumatology (ACR) 20/50/70 Response Criteria incidence adverse events (AEI) primary outcomes. meta-analysis was performed random-effects model. quality each assessed according RoB 2. Of 1,036 full-text articles screened, 415 were included review. data from 37,839 participants. EACM associated higher ACR responses: 20 (RR: 1.2332; 95% CI: 1.1852 1.2831, p < 0.0001), 50 1.3782; 1.2936 1.4684, 70 1.7084; 1.5555 1.8762, well favorable AEI (OR: 0.3977; 0.3476 0.4551, indicating both better efficacy safety compared alone. These patterns consistent eight secondary outcomes measuring pain, inflammation, disease activity RA. Subgroup analyses showed that EACM's effects independent control type. Through analysis polyherbal prescription dataset, we identified 18 key herbs 16 significant rules, further supported by relevant preclinical evidence. synergistic combinations anticipated most pharmacologically influential contributing outcomes, substantiated analytical metrics including network topology intricate association pattern evaluations. findings suggest may serve valuable complementary strategy RA patients insufficiently managed In particular, given index integrates multiple aspects patients, results are expected provide decision support who do not respond therapy, medical economic reasons. Additionally, derived through multifaceted analysis, actively reflect clinicians' implicit preferences prescribing EACMs, important hypotheses research clinical application. However, qualitative quantitative improvements needed more definitive conclusions. Further prescriptions presented this will direction future research.

Language: Английский

Citations

0
Emerging Mechanisms and Biomarkers Associated with T-Cells and B-Cells in Autoimmune Disorders DOI
Azhagu Madhavan Sivalingam

Clinical Reviews in Allergy & Immunology, Journal Year: 2025, Volume and Issue: 68(1)

Published: Feb. 11, 2025

Language: Английский

Citations

0
Theory & practice of Treat-to-Target (T2T) in rheumatoid arthritis DOI
Jing He, Yifan Wang,

Qinghong Liu

et al.

Best Practice & Research Clinical Rheumatology, Journal Year: 2024, Volume and Issue: unknown, P. 102018 - 102018

Published: Nov. 1, 2024

Language: Английский

Citations

1
Initial survey of UK rheumatologists to inform a national cardio-rheumatology strategy DOI

Amr Mohammed,

Rudresh Shukla,

Simon E. Fisher

et al.

Lara D. Veeken, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 15, 2024

Journal Article Accepted manuscript Initial survey of UK rheumatologists to inform a national cardio-rheumatology strategy Get access Amr Mohammed, Mohammed Division Cardiovascular Sciences, Faculty Biology, Medicine & Health, University Manchester, Search for other works by this author on: Oxford Academic PubMed Google Scholar Rudresh Shukla, Shukla Centre Musculoskeletal Research, Simon Fisher, Fisher NIHR-BHF Partnership, Oxford, Maya H Buch UKNIHR Manchester Biomedical Research Centre, NHS Foundation Trust, Corresponding and address: Professor Buch, Dermatological Sciences/School Biological AV Hill Building, Road, UK, M13 9PT, Email: [email protected] Telephone: +44 (0)161 306 0696 Rheumatology, keae567, https://doi.org/10.1093/rheumatology/keae567 Published: 16 October 2024 history Received: 17 July Revision received: 30 September Accepted: 07

Language: Английский

Citations

0