Embedding Emotion Concepts in Cognitive Maps

Neuroscience & Biobehavioral Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 106089 - 106089

Published: March 1, 2025

Emotion knowledge is organized in a two-dimensional space known as the affective circumplex, which thought to develop from core feelings and co-occurrence of emotional events. Neural studies reveal that emotion concepts cognitive maps abstract are represented hippocampal-prefrontal systems. We propose circumplex formed by learning transitions between concepts, process mediated reciprocal network involving hippocampal cells encode grid medial entorhinal ventral prefrontal cortices relations them. anticipate testing this hypothesis will shed light on debate about whether emotions biologically basic or constructed dimensions.

Language: Английский

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Emergence of orthogonal hippocampal representations during spatial learning

Learning & Behavior, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Sun et al. (2025) reveal the progressive, dynamic changes in response properties of thousands hippocampal neurons as mice learn a conditional discrimination while moving along virtual linear track. At end training, separate orthogonalized ensemble codes, reflecting state machine, capture inherent structure task dissociating outcomes.

Language: Английский

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Neural mechanisms of cognitive generalization across species: From hippocampus to cortex

Brain medicine :, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 13

Published: May 20, 2025

How do brains take what they have learned and apply it to new situations? This fundamental question sits at the core of cognitive generalization—a crucial ability that allows organisms adapt novel circumstances by drawing on prior experiences. While this mental flexibility enhances survival across species, underlying neural mechanisms connecting different brain regions in rodents, primates, humans remain poorly understood. Our review maps these pathways generalization from hippocampus cortex evolutionary spectrum. We show how hippocampal remapping replay processes create abstract rules during generalization, with subregions handling distinct memory types. The prefrontal emerges as essential for rule-based categorization all species studied, while orbitofrontal drives value-based decision-making, posterior parietal guides through perceptual processing past explore circuitry examine similar structures their associated behaviors are species. Additionally, we discuss disruptions manifest various neurological conditions corresponding regions. comprehensive analysis not only clarifies foundations but also suggests promising directions interventions targeting related disorders.

Language: Английский

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What dopamine teaches depends on what the brain believes

Nature Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: May 28, 2025

Language: Английский

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