Benign non-immune cells in tumor microenvironment DOI Creative Commons
Shaowen Liu, Chunhui Liu, Yuan He

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: April 3, 2025

The tumor microenvironment (TME) is a highly complex and continuous evolving ecosystem, consisting of diverse array cellular non-cellular components. Among these, benign non-immune cells, including cancer-associated fibroblasts (CAFs), adipocytes, endothelial cells (ECs), pericytes (PCs), Schwann (SCs) others, are crucial factors for development. Benign within the TME interact with both immune cells. These interactions contribute to progression through direct contact indirect communication. Numerous studies have highlighted role that exert on potential tumor-promoting mechanisms via multiple signaling pathways factors. However, these may play different roles across cancer types. Therefore, it important understand based heterogeneity. A deep understanding allows us develop novel therapies by targeting In this review, we will introduce several types according heterogeneity their in TME.

Language: Английский

Engineering adipocytes for cancer treatment DOI
Claire Greenhill

Nature Reviews Endocrinology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 20, 2025

Language: Английский

Citations

0
2024 ASHG Scientific Achievement Award DOI Creative Commons
Nadav Ahituv

The American Journal of Human Genetics, Journal Year: 2025, Volume and Issue: 112(3), P. 473 - 477

Published: March 1, 2025

Language: Английский

Citations

0
Fighting cancer with fat DOI

Gabrielle Brewer

Nature reviews. Cancer, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Language: Английский

Citations

0
Benign non-immune cells in tumor microenvironment DOI Creative Commons
Shaowen Liu, Chunhui Liu, Yuan He

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: April 3, 2025

The tumor microenvironment (TME) is a highly complex and continuous evolving ecosystem, consisting of diverse array cellular non-cellular components. Among these, benign non-immune cells, including cancer-associated fibroblasts (CAFs), adipocytes, endothelial cells (ECs), pericytes (PCs), Schwann (SCs) others, are crucial factors for development. Benign within the TME interact with both immune cells. These interactions contribute to progression through direct contact indirect communication. Numerous studies have highlighted role that exert on potential tumor-promoting mechanisms via multiple signaling pathways factors. However, these may play different roles across cancer types. Therefore, it important understand based heterogeneity. A deep understanding allows us develop novel therapies by targeting In this review, we will introduce several types according heterogeneity their in TME.

Language: Английский

Citations

0