Immobilization of nickel on Kryptofix 222 modified Fe3O4@PEG core‐shell nanosphere for the clean synthesis of 2‐Aryl‐2,3‐dihydroquinazolin‐4(1H)‐ones DOI
Akram Taghizadeh, Nader Noroozi Pesyan, Hassan Alamgholiloo

et al.

Applied Organometallic Chemistry, Journal Year: 2022, Volume and Issue: 36(9)

Published: June 21, 2022

The development of green‐based nanostructures is extremely compelling for their implementation in the catalytic arena. In this study, a new type magnetically core‐shell nanocomposite was successfully designed to be used as green catalyst synthesis 2,3‐dihydroquinazolin‐4(1 H )‐ones under ultrasonic irradiation. Initially, magnetic Fe 3 O 4 nanoparticle (NP) cores were fabricated via co‐operation method and subsequently coated with polyethylene glycol (PEG). After that, macro‐bicyclic Kryptofix 222 (KP222) functionalized on surface @PEG graft stabilization nickel metal. obtained Ni@KP222/Fe characterized by FT‐IR (Fourier Transform Infrared), wide‐angle XRD (X‐ray Powder Difraction), FESEM (Field Emiossion Scanning Electron Microscopy), TEM (Transmission VSM (Vibrating‐Sample Magnetometer), TGA‐DTA (Thermogravimetrtic Analysis‐ Differential Thermal Analysis), DLS (Dynamic Light Scattering), BET (Brunauer–Emmett–Teller) spectroscopy technique. findings indicated that high‐affinity KP222 ligand Ni 2+ ultrasound irradiation catalyzed synergistically formation )‐ones. benzaldehydes electron‐withdrawing electron donor groups could react well amino benzamide 5 min, indicating reaction not sensitive electronic effects. Furthermore, reusability test revealed successful recyclability six runs. current study provided rational design multifunctional catalysts applications.

Language: Английский

Synthesis and characterization of a new Schiff-base complex of copper on magnetic MCM-41 nanoparticles as efficient and reusable nanocatalyst in the synthesis of tetrazoles DOI
Mohsen Nikoorazm, Bahman Tahmasbi,

Shahab Gholami

et al.

Polyhedron, Journal Year: 2023, Volume and Issue: 244, P. 116587 - 116587

Published: Aug. 12, 2023

Language: Английский

Citations

46
Metal-organic framework-based nanostructured catalysts: Applications in efficient organic transformations DOI
Changlei Xia, Jiamin Wu, Seyed Ali Delbari

et al.

Molecular Catalysis, Journal Year: 2023, Volume and Issue: 546, P. 113217 - 113217

Published: May 27, 2023

Language: Английский

Citations

30
Fe3O4/SiO2 decorated trimesic acid-melamine nanocomposite: a reusable supramolecular organocatalyst for efficient multicomponent synthesis of imidazole derivatives DOI Creative Commons

Babak Fattahi,

Mohammad G. Dekamin

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Jan. 9, 2023

Abstract This article describes supramolecular Fe 3 O 4 /SiO 2 decorated trimesic acid-melamine (Fe -TMA-Me) nanocomposite that can be prepared with features combine properties of different materials to fabricate a structurally unique hybrid material. In particular, we have focused on design, synthesis and evaluation heterogeneous magnetic organocatalyst containing acidic functional-groups for the biologically important imidazole derivatives in good excellent yields. The introduced -TMA-Me nanomaterial was characterized by techniques such as FTIR, XRD, EDX, FESEM, TEM, TGA DTA. As noteworthy point, catalytic system recycled reused more than seven consecutive runs while its high activity remains under optimized conditions.

Language: Английский

Citations

26
Heterogenous copper(II) schiff-base complex immobilized mesoporous silica catalyst for multicomponent biginelli reaction DOI

Selvi Arumugam,

Senthilkumar Nangan, Natesan Thirumalaivasan

et al.

Journal of Organometallic Chemistry, Journal Year: 2023, Volume and Issue: 998, P. 122804 - 122804

Published: July 2, 2023

Language: Английский

Citations

25
A novel recyclable hydrolyzed nanomagnetic copolymer catalyst for green, and one-pot synthesis of tetrahydrobenzo[b]pyrans DOI Creative Commons
Behrooz Maleki,

Samaneh Sedigh Ashrafi,

Pouya Ghamari Kargar

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 28, 2024

Language: Английский

Citations

13
New Ionic Liquid Forms of Antituberculosis Drug Combinations for Optimized Stability and Dissolution DOI Creative Commons

Hanan E. Rasmy,

Sara A. Abouelmagd, Hany S.M. Ali

et al.

AAPS PharmSciTech, Journal Year: 2025, Volume and Issue: 26(1)

Published: Jan. 8, 2025

Abstract Isoniazid (INH) and rifampicin (RIF) are the two main drugs used for management of tuberculosis. They often as a fixed drug combination, but their delivery is challenged by suboptimal solubility physical instability. This study explores potential active pharmaceutical ingredient-ionic liquids (API-ILs) to improve physicochemical properties INH RIF. Antitubercular drugs, INH, or RIF, were paired with different counter ions (ascorbic acid (AsA), citric (CA), tartaric (TA), benzoic (BA), salicylic (SA), p-amino (PAS)) using solvent evaporation method. RIF API-ILs formed successfully AsA CA ions. IL formation was examined analyzed Fourier transform infrared (FTIR) spectroscopy, x-ray powder diffraction (XRPD), polarized optical microscopy (POM). XRPD POM confirmed amorphous nature, while FTIR analysis demonstrated contribution hydrogen bonding formation. enhanced storage stability + mixture in presence CA. Moreover, RIF-CA significantly increased rate extent dissolution. An effect that unattainable RIF/CA mixture. Thus, API-IL not only enhances dissolution also facilitates preparation stable, compatible INH-RIF combinations. Graphical

Language: Английский

Citations

1
Ultrasound-Promoted preparation and application of novel bifunctional core/shell Fe3O4@SiO2@PTS-APG as a robust catalyst in the expeditious synthesis of Hantzsch esters DOI Creative Commons

Peyman Shakib,

Mohammad G. Dekamin, Ehsan Valiey

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: May 17, 2023

In this work, D-(-)-α-phenylglycine (APG)-functionalized magnetic nanocatalyst (Fe3O4@SiO2@PTS-APG) was designed and successfully prepared in order to implement the principles of green chemistry for synthesis polyhydroquinoline (PHQ) 1,4-dihydropyridine (1,4-DHP) derivatives under ultrasonic irradiation EtOH. After preparing nanocatalyst, its structure confirmed by different spectroscopic methods or techniques including Fourier transform infrared (FTIR) spectroscopy, energy-dispersive X-ray spectroscopy (EDS), field emission scanning electron microscopy (FESEM), diffraction (XRD), vibrating sample magnetometer (VSM) thermal gravimetric analysis (TGA). The performance Fe3O4@SiO2@PTS-APG nanomaterial, as a heterogeneous catalyst Hantzsch condensation, examined various conditions. yield products controlled conditions reach more than 84% just 10 min, which indicates high along with synergistic effect irradiation. identified melting point well FTIR 1H NMR methods. is easily from commercially available, lower toxic thermally stable precursors through cost-effective, highly efficient environmentally friendly procedure. advantages method include simplicity operation, reaction mild conditions, use an benign source, obtaining pure efficiency short times without using tedious path, all them address important principles. Finally, reasonable mechanism proposed preparation presence bifunctional nanocatalyst.

Language: Английский

Citations

19
Magnetic decorated 5-sulfosalicylic acid grafted to chitosan: A solid acid organocatalyst for green synthesis of quinazoline derivatives DOI Creative Commons

Reyhaneh Peyvasteh Sourkouhi,

Mohammad G. Dekamin, Ehsan Valiey

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2024, Volume and Issue: 7, P. 100420 - 100420

Published: Jan. 3, 2024

In this research, a new magnetically decorated multifunctional solid acid was designed and prepared conveniently by grafting of 5-sulfosalicylic (SSA) onto the chitosan (CS) backbone using toluene-2,4-diisocyanate (TDI) linker for first time. The obtained magnetic biopolymeric nanomaterial, CS-TDI-SSA-Fe3O4, properly characterized spectroscopic, microscopic, or analytical methods including FT-IR, EDX, XRD, BET, FESEM, TGA, VSM. supramolecular CS-TDI-SSA-Fe3O4 nanocomposite investigated, as heterogeneous organocatalyst, to promote three-component synthesis 2,3-dihydroquinazoline-4(1H)-one derivatives under green conditions. acidic nanocatalyst demonstrated highly efficient activity wide range quinazoline derivatives, an important pharmaceutical scaffold, through multicomponent strategy. reaction proceeds very well in presence EtOH afford corresponding (DHQ) high excellent yields. key advantages present protocol are use novel, renewable, biopolymeric, biodegradable simple procedure preparation hybrid material. Furthermore, catalyst can be used at least five times DHQ with slight decrease its catalytic activity.

Language: Английский

Citations

6
Aluminium-based ionic liquid grafted on biochar as a heterogeneous catalyst for the selective synthesis of tetrazole and 2,3-dihydroquinazolin 4(1H)-one derivatives DOI Creative Commons
Masoomeh Norouzi, Parisa Moradi,

Maryam Khanmoradi

et al.

RSC Advances, Journal Year: 2023, Volume and Issue: 13(50), P. 35569 - 35582

Published: Jan. 1, 2023

2,3-Dihydroquinazolin-4(1H)-one and tetrazole are a class of nitrogen-containing heterocyclic compounds that play an important role in drug design part many biological industrial compounds. In this study, aluminium-based ionic liquid grafted onto biochar surface (BC/[TESPMI]AlCl4) was synthesized used as catalyst for the synthesis series derivatives including 2,3-dihydroquinazolin-4(1H)-ones ethanol at reflux conditions tetrazoles PEG-400 110 °C. All products were obtained with good selectivity yield 90 to 97%. The thoroughly characterized using various techniques such thermogravimetric analysis (TGA), energy-dispersive X-ray spectroscopy (EDX), powder diffraction (PXRD), scanning electron microscopy (SEM), inductively coupled plasm (ICP), transmission (TEM), which confirmed successful chemical grafting. This methodology has several advantages, shorter reaction time, high product, recyclability catalyst. remained active five cycles.

Language: Английский

Citations

14
Nickel‐asparagine complex fixed on a magnetic substrate as a precursor for preparing substituted acridines DOI

Maryam Abbaszadehghan,

Ahmad Poursattar Marjani, Sepideh Bibak

et al.

Applied Organometallic Chemistry, Journal Year: 2023, Volume and Issue: 37(11)

Published: Sept. 8, 2023

In this work, an efficient, novel, retrievable, and magnetic heterogeneous nanocatalyst, Fe 3 O 4 @CPTMS@Asp@Ni was successfully fabricated using nanoparticles as the core that were coated with surfactant 3‐chloropropyltrimethoxysilan deposited asparagine nickel metal can be used in multicomponent reactions for synthesis of acridines derivatives high yield short reaction times. The virtue obtained nanocatalyst identified transmission electron microscopy, scanning Fourier transform infrared spectroscopy, X‐ray diffraction analysis, energy dispersive X‐ray, Brunauer–Emmett–Teller, vibrating sample magnetometry, Raman, thermogravimetric analysis. analysis studies demonstrate average crystallite sizes prepared are estimated to about 45.4 nm. Also, magnetometry measurement shows saturation magnetization values (Ms) 7 emu/g nanocatalyst. after steps, application preparation acridine‐1,8(2 H ,5 )‐diones has been investigated. Then evaluate assess efficiency mentioned above, its effect on divergent via a one‐pot, three‐component condensation cyclic 1,3‐dione, aryl glyoxal, ammonium acetate water green solvent studied. when investigating reusability catalyst, it observed could reused at least five times without losing efficiency. High efficiency, outstanding yields quick intervals, easy separation field, possessing significant benefits attained

Language: Английский

Citations

12