Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 12, 2024
Waterborne
pathogens
are
harmful
microorganisms
transmitted
through
water
sources.
Early
and
rapid
pathogen
detection
is
important
for
preventing
illnesses
implementing
stringent
safety
measures
to
minimize
the
risk
of
contamination.
This
work
introduces
a
miniaturized
all-solid-state
potentiometric
ion
flux
immunosensor
label-free
waterborne
pathogens.
A
screen-printed
silver/silver
chloride
electrode
coated
with
reference
membrane
polyurethane
as
an
was
combined
solid-state
contact
ion-selective
(ISE).
An
ISE
constructed
on
laser-induced
graphene
by
coating
it
cationic
marker
carboxylated
poly(vinyl
chloride)-based
immobilizing
antibodies
controlling
fluxes
membrane.
Proof-of-concept
achieved
detecting
Drug Development and Industrial Pharmacy,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 16
Published: Jan. 21, 2025
This
article
provides
a
substantial
review
of
recent
research
and
comparison
on
molecular
dynamics
potentials
to
determine
which
are
most
suitable
for
simulating
the
phenomena
in
graphene-based
nanomaterials
(GBNs).
GBNs
gain
significant
attention
due
their
remarkable
properties
potential
applications,
notably
nanomedicine.
However,
physical
chemical
characteristics
toward
macromolecules
that
justify
nanomedical
applications
not
yet
fully
understood.
The
interaction
through
dynamic
simulation
offers
benefits
inorganic
molecules
like
GBNs,
with
necessary
adjustments
account
interactions,
or
thermodynamic
conditions.
In
this
review,
we
explore
various
(force
fields)
used
simulate
interactions
nanomaterials.
Additionally,
offer
brief
overview
drawbacks
each
force
fields
available
analysis
assess
one
is
study
We
identify
compare
analyzing
providing
insights
into
suitability
specific
specification
its
purpose
can
be
further
application
GBNs.
hold
promise
nanomedicine,
but
must
thoroughly
studied
safe
clinical
use.
Molecular
simulations,
using
either
reactive
non-reactive
MD
depending
expected
changes,
essential
accurately
modeling
these
properties,
requiring
careful
selection
based
application.
Chemosensors,
Journal Year:
2025,
Volume and Issue:
13(4), P. 122 - 122
Published: April 2, 2025
Flexible,
wearable
biomedical
sensors
based
on
laser-induced
graphene
(LIG)
have
garnered
significant
attention
due
to
a
straightforward
fabrication
process
and
exceptional
electrical
mechanical
properties.
However,
most
relevant
studies
rely
commercial
polyimide
precursors,
which
suffer
from
inadequate
biocompatibility
weak
adhesion
between
the
precursor
material
LIG
layer.
To
address
these
challenges,
we
synthesized
cross-linked
polyurethanes
(PUs)
with
good
used
them
as
substrates
for
LIG-based
pulse
sensors.
During
fabrication,
employed
two
methods
of
transfer
achieve
optimal
yield.
We
adjusted
thickness
PU
films
tailored
their
physicochemical
properties
by
varying
soft
segment
content
sensor
performance.
Our
findings
demonstrate
that
success
is
strongly
influenced
structure
composition
polymeric
substrate.
Tensile
testing
revealed
increasing
in
significantly
improved
tensile
strength,
elongation
at
break,
flexibility,
50
wt.%
(PU-50)
showing
best
exhibited
minimal
sensitivity
humidity,
while
maintained
high
transparency
(>80%
500
nm),
PU-50
was
non-toxic,
less
than
5%
lactate
dehydrogenase
(LDH)
release
endothelial
cell
cultures,
confirming
its
biocompatibility.
Adhesion
tests
demonstrated
transferred
onto
stronger
compared
other
tested
substrates,
only
30%
increase
resistance
after
Scotch
tape
test,
ensuring
stability
The
substrate,
semicrystalline
PU-50,
yielded
superior
efficiency.
Among
all
sensors,
LIG/PU-50,
featuring
77
μm
thick
substrate
adhesion,
highest
signal-to-noise
ratio
(SNR).
This
study
showcases
skin-safe
LIG/PU-based
has
potential
applications
patch
medical
sports
monitoring.
