Microbiology Spectrum,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 10, 2024
ABSTRACT
Although
silver
is
known
for
its
antibacterial
activity,
exact
mode
of
action
remains
unclear.
In
our
previous
work,
we
described
AgNbO
3
nanoparticles
(AgNbO
NPs)
prepared
using
a
ceramic
method,
followed
by
high-energy
and
low-energy
ball-milling
processes,
which
exhibited
antimicrobial
activity
with
negligible
release
Ag
+
in
deionized
water.
Here,
investigated
thoroughly
the
these
NPs
against
Escherichia
coli
.
Drastic
morphological
changes
E.
were
observed
after
their
exposure
to
NPs.
addition
cellular
damage,
induced
production
reactive
oxygen
species
lipid
peroxidation,
likely
following
small
amounts
This
was
concluded
from
characterization
mutants
resistant
that
showed
cross-resistance
AgNO
,
impaired
harbored
key
mutation
two-component
regulatory
system
regulating
an
efflux
pump.
We
calculated,
however,
quantity
released
not
sufficient
itself
lead
bacterial
death.
propose
contact
combination
necessary
IMPORTANCE
Silver
but
Our
data
suggest
have
dual
effects
on
cell
both
are
required
lethal
action.
KIMIKA,
Journal Year:
2025,
Volume and Issue:
35(2), P. 1 - 13
Published: Feb. 24, 2025
Silver
nanoparticles
(AgNPs)
were
synthesized
using
an
aqueous
extract
of
papain
as
a
reducing
and
stabilizing
agent
for
use
in
the
fluorescence-based
sensing
B-vitamin,
folic
acid.
The
AgNPs
obtained
spherical
with
diameters
between
3-40
nm,
average
diameter
11.4
±
6.4
nm.
also
exhibited
surface
plasmon
resonance
(SPR)
at
420
nm
fluorescence
upon
excitation
UV
light.
addition
increments
acid
caused
quenching
AgNPs’
which
could
be
fitted
to
Stern-Volmer
equation.
limits
detection
(LOD)
quantification
(LOQ)
folate
sensors
1.510
μg
5.033
μg,
respectively.
Analysis
selected
over-the-counter
vitamin
mineral
supplements
showed
stark
discrepancies
declared
experimental
levels.
Thus,
it
was
inferred
that
other
substances,
such
metal
ions
vitamins
interfere
analysis.
While
papain-AgNPs
seems
promising,
more
work
should
done
improved
selectivity
specificity
folate.
BMC Plant Biology,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: April 21, 2025
Abstract
Background
Anthracnose,
caused
by
Colletotrichum
capsici
,
is
a
significant
fungal
disease
affecting
chilli
crops,
leading
to
yield
losses
of
10–25%.
Traditional
control
methods,
primarily
chemical
fungicides,
not
only
pose
risks
the
environment
and
soil
health
but
also
threaten
public
safety.
In
contrast,
nanotechnology
presents
promising
eco-friendly
alternative,
leveraging
unique
properties
nanoparticles,
such
as
their
small
size
high
surface-to-volume
ratio,
effectively
manage
infections
with
minimal
environmental
impact.
Results
This
study
investigates
synthesis,
characterization,
antifungal
activity
silver
nanoparticles
(Ag-NPs)
synthesized
from
guava
leaf
extract
against
fruit
rot.
UV-Vis
spectroscopy
confirmed
synthesis
Ag-NPs
peak
absorption
at
431
nm.
X-ray
diffraction
(XRD)
analysis
revealed
crystalline
structure
an
average
particle
42.5
nm,
while
scanning
electron
microscopy
(SEM)
showed
spherical
sizes
ranging
30.5
nm
50.3
across
different
samples.
Fourier
transform
infrared
(FTIR)
identified
functional
groups
involved
in
ion
reduction.
Zeta
500.1
1.0
62.4
262.8
178.8
for
samples
S1
through
S5,
respectively.
assays,
50
ppm
exhibited
highest
mycelial
growth
inhibition
(47.9%),
protective
(87%)
curative
(93%)
effects.
Additionally,
in-vitro
leaflet
demonstrated
86%
C.
ppm,
highlighting
its
potential
effective
agent
managing
Conclusions
rapid,
method
synthesizing
using
extract,
showing
rot
.
The
results
highlight
effectiveness
both
applications,
offering
sustainable
alternative
fungicides.
Future
research
should
focus
on
scaling
up
process
industrial
exploring
long-term
impact,
assessing
broader
applicability
other
phytopathogenic
diseases
various
crops.
Summary
Silver
inhibit
ppm.
highlights
eco-friendly,
rapid
fungicides
disease.
Clinical
trial
number
Not
applicable.
Graphical
ChemistrySelect,
Journal Year:
2025,
Volume and Issue:
10(17)
Published: May 1, 2025
Abstract
Copper
oxide
nanoparticles
were
synthesized
by
ecofriendly
method
using
aqueous
extract
of
Brassica
juncea
(L.)
Czern
seeds.
Thus,
obtained
BJ‐CuO
NPs
characterized
TEM,
EDX,
Raman
spectra,
DLS,
zeta
potential,
UV–vis,
FTIR,
XRD,
and
SEM
techniques.
XRD
analysis
revealed
monoclinic
structure
with
18
nm
crystallite
size.
studies
confirmed
the
spherical
morphology
produced
NPs,
further
supported
through
TEM
(17.67
±
5.45
nm).
spectra
showed
peaks
at
292,
340,
626
cm
−1
,
which
is
attributed
to
active
modes
for
Cu–O
stretching
(Ag
+
2Bg).
The
stability
colloidal
suspension
was
proved
DLS
potential
value
−34.5
mV.
had
shown
significant
biological
activities
IC
50
values
in
µg/mL,
namely,
i)
antioxidant
(72.21),
ii)
anti‐inflammatory
(77.77),
iii)
antidiabetic
activity
(71.36).
Further,
cytotoxicity
on
A549
MCF‐7
cell
lines
MTT
test
reveals
moderate
effect
40.68
86.62
µg/mL.
On
screening
antibacterial
antifungal
against
various
strains,
it
shows
E.
coli
(18
0.30)
A.
Niger
0.61).
These
results
indicate
that
hold
applications
future
drug
development.
